{"id":3680,"date":"2017-01-19T17:04:14","date_gmt":"2017-01-19T17:04:14","guid":{"rendered":"https:\/\/www.wma.net\/wp-content\/uploads\/2016\/11\/wmj201503.pdf"},"modified":"2017-01-19T17:04:14","modified_gmt":"2017-01-19T17:04:14","slug":"wmj201503-2","status":"inherit","type":"attachment","link":"https:\/\/www.wma.net\/fr\/publications\/world-medical-journal\/wmj201503-2\/","title":{"rendered":"wmj201503"},"author":2,"comment_status":"open","ping_status":"closed","template":"","meta":[],"acf":[],"description":{"rendered":"<p class=\"attachment\"><a href='https:\/\/www.wma.net\/wp-content\/uploads\/2016\/11\/wmj201503.pdf'>wmj201503<\/a><\/p>\n<p>COUNTRY<br \/>\nvol. 61<br \/>\nMedicalWorld<br \/>\nJournal<br \/>\nOfficial Journal of The World Medical Association, Inc.<br \/>\nISSN 2256-0580<br \/>\nNr. 3, October 2015<br \/>\nContents<br \/>\nDoctor in the World and Medicines .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t81<br \/>\nInterview with Dr. Xavier Deau, President of the World Medical Association .  .  .  .  .  .  .  .  .  .  .  . \t82<br \/>\nInterview with Dr. Zsuzsanna Jakab, WHO Regional Director for Europe . .  .  .  .  .  .  .  .  .  .  .  .  .  . \t83<br \/>\nInterview with Dr. Jacques de Haller, Vice\u00a0President, President Elect<br \/>\n2016\u20132018 (Switzerland) of CPME .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t86<br \/>\nFrom Zoonosis to Pandemic .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t87<br \/>\nHealth and Asylum Seekers in Europe .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t89<br \/>\nInternational Committee of the Red Cross activities for refugees\/displaced persons<br \/>\nin the Middle East .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t98<br \/>\nSubjectivity and Narratives in Primary Care: A Person Centered Issue. .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t106<br \/>\nThe Integration of Mental Health and Primary Care: A Person-centered Approach. .  .  .  .  .  .  . \t109<br \/>\nThe Road to Paris: What is at Stake for Health in COP21 Negotiations? .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t114<br \/>\nMore Good Days: Person-Centered Care at\u00a0the End of Life. .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  .  . \t119<br \/>\nBACK TO CONTENTS<br \/>\n81<br \/>\nEditorial<br \/>\nIn the modern world, pharmaceutical business is an honorary sec-<br \/>\nond runner-up among the most profiteering businesses, right after<br \/>\ntrafficking in humans and in drugs. With the recent shipping of<br \/>\nrefugees to Europe, the winner and the first runner-up have merged<br \/>\ninto one.The pharmaceutical business mostly is a quite legal, trans-<br \/>\nparent and straight one,except for counterfeit medicines which take<br \/>\nup 10\u201315% of the market. For a medical doctor, global information<br \/>\navailable in 2015 is interesting due to the following patterns:<br \/>\n(I) clinical research is becoming increasingly costly, new drugs are<br \/>\ngetting discovered less,generics are taking up higher proportion and<br \/>\neven prevail in the market. Countries and regions happen to over-<br \/>\nlook the letter and spirit of the Helsinki Declaration, particularly in<br \/>\nrespect of the work of the Ethics Committees;<br \/>\n(II) the pharmaceutical industry is losing interest in small-size mar-<br \/>\nkets, production costs are increasing due to quality control require-<br \/>\nments, whereas compensation systems in the countries fail to evolve<br \/>\ntogether with the changing market. The pharmaceutical business is<br \/>\nfacing new challenges, which are shortages of production capacities<br \/>\nand limited availability of raw materials;<br \/>\n(III) the accessibility of medicines and counterfeit drugs is becom-<br \/>\ning a global problem as a result of internet pharmacies chains, re-<br \/>\nexport with the purpose of price arbitrage and parallel import;<br \/>\n(IV) refugee crisis in Europe (also the flows of refugees in Asia,<br \/>\nAustralia,the Republic of South Africa and some countries in Latin<br \/>\nAmerica) involve uncertainties about the immigrants\u2019state of health,<br \/>\ninfectious and parasitic diseases, vaccination against dangerous dis-<br \/>\neases, e.g. poliomyelitis.With some countries failing financially (e.g.<br \/>\nGreece is unable to settle its payments for the delivered medicines<br \/>\nfor quite a while), selected segments of the drugs market start pan-<br \/>\nicking, and a tendency emerges to stock up some medicines, instead<br \/>\nof placing them on the market;<br \/>\n(V) there is not enough research as to the dosages for senior patients<br \/>\nand children: it is still believed that patients, though dissimilar as to<br \/>\nage, gender or physical capacities, should get prescribed medicines<br \/>\nin equal dosages;<br \/>\n(VI) most of clinical trials are shifted to developing countries,which<br \/>\nleads to a mistrust in the trial results in developed countries;<br \/>\n(VII) resistance to drugs is increasing, and not exclusively to anti-<br \/>\nbiotics. The body cells tend to develop biochemical dependency on<br \/>\nmedicines, and dosages need to be raised;<br \/>\n(VIII) polypragmasia as a medical problem in industrial and devel-<br \/>\noped economies.Both in Europe and America,the population in the<br \/>\nage group beyond 50 are taking more than six different drugs daily,<br \/>\nplus a number of food supplements and over-the-counter medicines.<br \/>\nFor the time being, no proper research has been done, and there is<br \/>\na lack of understanding how much food supplements and other<br \/>\nchemically active substances are being consumed along with medi-<br \/>\ncines (e.g. illegal psychoactive substances, sports drinks and powders<br \/>\netc.). Advertising promotes unreasonable consumption of medicines<br \/>\nand food supplements, especially among senior citizens;<br \/>\n(IX) biomedicines \u2013 medicines of the future \u2013 and their biological<br \/>\nequals appear in the market without adequate knowledge and un-<br \/>\nderstanding on the part of doctors and pharmacists,they are scarcely<br \/>\nused due to the high price;<br \/>\n(X) medicines launched to the market at an early stage and having<br \/>\nheightened vigilance, which have been subject to less trials and who<br \/>\nmay have more side effects, especially when taken with other medi-<br \/>\ncines. Individualised medicines are being released to the market as<br \/>\nwell;<br \/>\n(XI) non-cooperating patients. 25\u201340% of patients are non-cooper-<br \/>\nating when receiving treatment: they are neither willing nor moti-<br \/>\nvated to get well again.10\u201320% of population prefer to be treated by<br \/>\ncharlatans, healers and witchdoctors, or by psychologists or psycho-<br \/>\ntherapists without any medical education etc.. Alongside with the<br \/>\ndrugs prescribed by the doctor, nature therapy, Ayurveda medicines<br \/>\nand other chemically active substances are used;<br \/>\n(XII) medicines are continuously being discarded in open environ-<br \/>\nment and may end up into food; in most cases the non-used medi-<br \/>\ncines still do not get destroyed.<br \/>\nThis list could be compiled in a different order and complemented<br \/>\nwith other items. In global medicine, the influence of the pharma-<br \/>\nceutical industry is increasing, people are ageing, funds from gov-<br \/>\nernments or insurance are not sufficient to pay for medicines.<br \/>\nThe World Medical Association has to analyse the developments in<br \/>\nthe medicines market all over again.<br \/>\nDr. P\u0113teris Apinis<br \/>\nPresident of the Latvian Medical Association<br \/>\nEditor in Chief<br \/>\nDr. P\u0113teris Apinis, Latvian Medical Association, Skolas iela 3, Riga, Latvia<br \/>\nPhone +371 67 220 661<br \/>\npeteris@arstubiedriba.lv, editorin-chief@wma.net<br \/>\nCo-Editor<br \/>\nProf. Dr. med. Elmar Doppelfeld, Deutscher \u00c4rzte-Verlag, Dieselstr. 2, D-50859 K\u00f6ln, Germany<br \/>\nAssistant Editor<br \/>\nMaira Sudraba, Velta Poz\u0146aka; lma@arstubiedriba.lv<br \/>\nJournal design and<br \/>\ncover design by<br \/>\nP\u0113teris Gricenko<br \/>\nLayout and Artwork<br \/>\nThe Latvian Medical Publisher, \u201cMedic\u012bnas apg\u0101ds\u201d, President Dr. Maija \u0160etlere, Skolas street 3, Riga, Latvia<br \/>\nPublisher<br \/>\nThe Latvian Medical Association, \u201cLatvijas \u0100rstu biedr\u012bba\u201d,<br \/>\nSkolas street 3, Riga, Latvia.<br \/>\nISSN: 2256-0580<br \/>\nDr. Xavier DEAU<br \/>\nWMA President<br \/>\nConseil National de l\u2019Ordre des<br \/>\nM\u00e9decins (CNOM)<br \/>\n180, Blvd. Haussmann<br \/>\n75389 Paris Cedex 08<br \/>\nFrance<br \/>\nDr. Donchun SHIN<br \/>\nWMA Chairperson of the Finance<br \/>\nand Planning Committee<br \/>\nKorean Medical Association<br \/>\n46-gil Ichon-ro<br \/>\nYongsan-gu, Seoul 140-721<br \/>\nKorea<br \/>\nProf. Dr. Frank Ulrich<br \/>\nMONTGOMERY<br \/>\nWMA Vice-Chairperson of Council<br \/>\nBundes\u00e4rztekammer<br \/>\nHerbert-Lewin-Platz 1 (Wegelystrasse)<br \/>\n10623 Berlin<br \/>\nGermany<br \/>\nDr. Margaret MUNGHERERA<br \/>\nWMA Immediate Past-President<br \/>\nUganda Medical Association<br \/>\nPlot 8, 41-43 circular rd., P.O.<br \/>\nBox 29874<br \/>\nKampala<br \/>\nUganda<br \/>\nDr. Joseph HEYMAN<br \/>\nWMA Chairperson<br \/>\nof the Associate Members<br \/>\n163 Middle Street<br \/>\nWest Newbury, Massachusetts 01985<br \/>\nUnited States<br \/>\nDr. Masami ISHII<br \/>\nWMA Treasurer<br \/>\nJapan Medical Assn<br \/>\n2-28-16 Honkomagome<br \/>\nBunkyo-ku<br \/>\nTokyo 113-8621<br \/>\nJapan<br \/>\nSir Michael MARMOT<br \/>\nWMA President-Elect<br \/>\nBritish Medical Association<br \/>\nBMA House,Tavistock Square<br \/>\nLondon WC1H 9JP<br \/>\nUnited Kingdom<br \/>\nDr. Heikki P\u00c4LVE<br \/>\nWMA Chairperson of the Medical<br \/>\nEthics Committee<br \/>\nFinnish Medical Association<br \/>\nP.O. Box 49<br \/>\n00501 Helsinki<br \/>\nFinland<br \/>\nDr. Miguel Roberto JORGE<br \/>\nWMA Chairperson of the Socio-<br \/>\nMedical Affairs Committee<br \/>\nBrazilian Medical Association<br \/>\nRua-Sao Carlos do Pinhal 324,<br \/>\nCEP-01333-903 Sao Paulo-SP<br \/>\nBrazil<br \/>\nDr. Ardis D. HOVEN<br \/>\nWMA Chairperson of Council<br \/>\nAmerican Medical Association<br \/>\nAMA Plaza, 330 N. Wabash,<br \/>\nSuite 39300<br \/>\n60611-5885 Chikago, Illinois<br \/>\nUnited States<br \/>\nDr. Otmar KLOIBER<br \/>\nSecretary General<br \/>\nWorld Medical Association<br \/>\n13 chemin du Levant<br \/>\n01212 Ferney-Voltaire<br \/>\nFrance<br \/>\nWorld Medical Association Officers, Chairpersons and Officials<br \/>\nOfficial Journal of The World Medical Association<br \/>\nOpinions expressed in this journal\u00a0\u2013 especially those in authored contributions\u00a0\u2013 do not necessarily reflect WMA policy or positions<br \/>\nwww.wma.net<br \/>\nDoctor in the World and Medicines<br \/>\nBACK TO CONTENTS<br \/>\n82 83<br \/>\nWMA News Public Health Care<br \/>\nQ.Global warming and emission gases are<br \/>\namong the world\u2019s most essential public<br \/>\nhealth problems. What initiatives can we<br \/>\nexpect from the WMA for the forthcom-<br \/>\ning Paris conference as to fighting global<br \/>\nwarming?<br \/>\nThe WMA will be present in Paris at the<br \/>\nCOP21, channelling the serious con-<br \/>\ncerns of physicians regarding the impact<br \/>\nof climate change on health. The health of<br \/>\nthe planet is our health. This is the mes-<br \/>\nsage that I would like to bring forward.<br \/>\nThe WMA has joined the Campaign \u201cOur<br \/>\nClimate, Our Health\u201d. It is a new campaign<br \/>\ncreated to mobilise the health profession in<br \/>\nthe lead up to the 2015 climate change ne-<br \/>\ngotiations in Paris. The Campaign is led by<br \/>\nthe World Health Organization in collabo-<br \/>\nration with the Global Climate and Health<br \/>\nAlliance. It aims to reach out to all parts of<br \/>\nthe health sector, communicating the links<br \/>\nbetween health and climate change, de-<br \/>\nmanding a stronger international deal, and<br \/>\nbuilding support around a common decla-<br \/>\nration\u00a0 \u2013 to be presented to negotiators in<br \/>\nParis this December. We will participate in<br \/>\nthe Climate and Health Summit which is<br \/>\nscheduled to take place on the 5th<br \/>\nof De-<br \/>\ncember in Paris in the framework of this<br \/>\nCampaign.<br \/>\nQ. Clean air, clean water and harmless<br \/>\nfood are the most important health pre-<br \/>\nconditions for global population. Right<br \/>\nnow, when the global oceans and seas are<br \/>\nbeing polluted with plastics and chemi-<br \/>\ncal products, it has an impact on each<br \/>\nsingle inhabitant on the Earth. We can<br \/>\neven call the polluting of the world with<br \/>\nchemicals a chemical war. What could<br \/>\nthe WMA do in order to reduce the glob-<br \/>\nal pollution with chemicals? Shouldn\u2019t<br \/>\nthe WMA take a more radical position<br \/>\nagainst the use of heavy metals (mercury,<br \/>\nbismuth), against pesticides, herbicides,<br \/>\nmineral substances and other substances<br \/>\nwhich inhibit the development of hor-<br \/>\nmonal system?<br \/>\nThe WMA\u2019s policies in the area of environ-<br \/>\nment have been developing over the last<br \/>\nyears with the expertise of its members. We<br \/>\nhave a clear position on climate change,<br \/>\nmercury products, chemicals, and more<br \/>\nrecently on air pollution. We have also set<br \/>\nup the environment caucus to promote ex-<br \/>\nchange of good practices and experiences<br \/>\nbetween the members. We could certainly<br \/>\nwork further on our policies. But most im-<br \/>\nportant, the challenge now is to make sure<br \/>\nthat our voice is finally heard, that strong<br \/>\ncommitments and actions are finally taken<br \/>\nby decision-makers. This is a matter of ur-<br \/>\ngency. Our planet is ill and we are all ac-<br \/>\ncountable. Mobilisation of all is what is<br \/>\nneeded today.<br \/>\nQ. Shouldn\u2019t the WMA develop its own<br \/>\nstrategy for fighting global warming<br \/>\nand use a variety of instruments, such as<br \/>\nstrong criticism of global polluters,or cre-<br \/>\nate a WMA award in recognition of the<br \/>\nmost successful pollution treatment and<br \/>\necological projects?<br \/>\nThe WMA has been increasingly active in<br \/>\nthe area of climate change nationally and<br \/>\nglobally through various means: the UN<br \/>\nprocess, the promotion of regular plat-<br \/>\nforms for discussion between NMAs and<br \/>\nalso through partnerships with the WHO<br \/>\nand non-governmental organisations,<br \/>\nactive in the area of health and environ-<br \/>\nment. I do not believe that another award<br \/>\nwill bring significant changes. Today we<br \/>\nneed concrete actions nationally and lo-<br \/>\ncally, we need to raise awareness amongst<br \/>\nthe health professionals, the public, the<br \/>\ndecision-makers. I\u00a0 nourish great hopes<br \/>\nthat the young generation will continue<br \/>\ncarrying that torch. As a matter of fact, the<br \/>\nJunior Doctors Network is extremely ac-<br \/>\ntive in putting health at the centre of the<br \/>\nclimate negotiations, and I am proud that<br \/>\nthe WMA embraces this new generation<br \/>\nof physicians.<br \/>\nInterview with Dr. Xavier Deau, President of the World Medical<br \/>\nAssociation<br \/>\nBy Dr. Peteris Apinis. September, 2015<br \/>\nXavier Deau<br \/>\n\u201cBetter Health for Europe: More Equitable<br \/>\nand Sustainable\u00a0\u2013 That is What We Work for\u201d<br \/>\nQ. The WHO Regional Office is a Euro-<br \/>\npean leader in public health area. Could<br \/>\nyou please update us on the progresses,<br \/>\nconcerns and main goals of the Region?<br \/>\nDuring the past few years, the WHO Eu-<br \/>\nropean Region made good progress in many<br \/>\nareas, but we must do more and we must<br \/>\ndo better.<br \/>\nOn key health indicators, such as life<br \/>\nexpectancy, Europeans are living longer<br \/>\nand the differences between countries in<br \/>\nhealth outcomes are shrinking: a clear<br \/>\nsign that inequalities are declining and<br \/>\nHealth 2020\u00a0\u2013 the WHO European pol-<br \/>\nicy framework developed and adopted by<br \/>\nall our 53 Member States\u00a0\u2013 works. How-<br \/>\never, the gap between the countries with<br \/>\nthe highest and lowest life expectancy is<br \/>\nstill 11 years.<br \/>\nThe Region is on track towards reduc-<br \/>\ning premature mortality due to decline<br \/>\nin cardio-vascular diseases (CVDs), and<br \/>\nEuropeans are reducing their health risk<br \/>\nbehaviours. But people in Europe still<br \/>\nsmoke and drink more than anywhere<br \/>\nelse in the world, and are among the most<br \/>\nobese.<br \/>\nWe are making progress in improving<br \/>\nwomen\u2019s health, but wide inequities be-<br \/>\ntween and within countries remain.The use<br \/>\nof modern, effective methods of contracep-<br \/>\ntion is alarmingly low in many countries.<br \/>\nSome countries have the highest abortion<br \/>\nrates in the world. Effective perinatal care<br \/>\nresulted in the decrease in the major killer<br \/>\nof mothers\u00a0\u2013 the severe obstetrical bleed-<br \/>\ning. Now is the time to focus on pre-exist-<br \/>\ning medical conditions\u00a0\u2013 such as diabetes,<br \/>\nobesity, CVD and mental diseases\u00a0\u2013 that<br \/>\nare exacerbated by pregnancy. More needs<br \/>\nto be done on sexual and reproductive<br \/>\nhealth and rights.<br \/>\nTransforming health services to match the<br \/>\nneeds of the 21st<br \/>\ncentury is the strategic pri-<br \/>\nority in our Region. Coordinated, integrat-<br \/>\ned health-service delivery towards people-<br \/>\ncentred care is the way forward.The Region<br \/>\nis scaling up efforts on strengthening health<br \/>\nsystems and public health capacity in order<br \/>\nto improve health outcomes in an equitable<br \/>\nmanner, ensuring financial protection, re-<br \/>\nsponsiveness and efficiency.<br \/>\nWe are addressing health-systems barriers<br \/>\nfor specific diseases and conditions, includ-<br \/>\ning communicable diseases and NCDs,<br \/>\nwhich are then translated into policy deci-<br \/>\nsions and actions. We are now broadening<br \/>\nthe focus to include environmentally sus-<br \/>\ntainable health systems.<br \/>\nAn extensive area of work in the Region<br \/>\nrelates to tackling public health emergen-<br \/>\ncies and crisis situations. Our aim is to en-<br \/>\nsure that our Member States are adequately<br \/>\nprepared to effectively detect and respond,<br \/>\nwhenever and wherever an emergency with<br \/>\nhealth consequences strikes. The recent Eb-<br \/>\nola outbreak in West Africa demonstrated<br \/>\nthat the international community is not suf-<br \/>\nficiently prepared to manage major health<br \/>\nhazards. This is a defining moment for<br \/>\nchange.We are fully committed to taking all<br \/>\nnecessary action.This is a global objective.In<br \/>\nthe Regional Office, we take an integrated,<br \/>\ngeneric, all-hazards and multisectoral ap-<br \/>\nproach to preparedness for both humanitar-<br \/>\nian and public health emergencies.<br \/>\nLet me stress: real improvements in health,<br \/>\nincluding the areas I just outlined, can be<br \/>\nachieved if we work across government. All<br \/>\nsectors, especially with those responsible for<br \/>\nsocial and fiscal policies, need to work in<br \/>\npartnership for better health for all.<br \/>\nIntersectoral action for health requires politi-<br \/>\ncal commitment.It should focus on key public<br \/>\nhealth priorities and upstream interventions<br \/>\nby addressing the determinants of health and<br \/>\nhealth equity,and strive for maximum impact<br \/>\nby creating win\u2013win partnerships.<br \/>\nDevelopment is impossible without better<br \/>\nhealth. Health is a precondition for alleviat-<br \/>\ning poverty, and an indicator and outcome<br \/>\nof progress towards a sustainable society.<br \/>\nMore decision-makers are making coherent<br \/>\nand interconnected government policies, with<br \/>\na strong intersectoral component, and using<br \/>\nHealth 2020 as the way forward. From 2010<br \/>\nto 2013, the proportion of countries with<br \/>\nnational health policies aligned with Health<br \/>\n2020 almost doubled: from 38% to 70%. And<br \/>\nthis is a great achievement so far.This progress<br \/>\ndemonstrates what we can do if we are com-<br \/>\nmitted and work together, but it also shows<br \/>\nthat we have many challenges ahead,confirm-<br \/>\ning that the key strategic directions of Health<br \/>\n2020 remain more relevant than ever before.<br \/>\nInterview with Dr. Zsuzsanna Jakab,<br \/>\nWHO Regional Director for Europe<br \/>\nBy Dr. Peteris Apinis. September, 2015<br \/>\nZsuzsanna Jakab<br \/>\nBACK TO CONTENTS<br \/>\n84 85<br \/>\nPublic Health CarePublic Health Care<br \/>\nOnly the governments that put health and<br \/>\nwell-being high on their social,economic and<br \/>\ndevelopment agenda will be able to overcome<br \/>\nthese challenges. Health is a political choice.<br \/>\nIn essence, Health 2020 supports making the<br \/>\nright political choices for health.Our key role<br \/>\nis to protect health as a universal value and<br \/>\nto promote it as a social and political goal for<br \/>\ngovernment and society as a whole.<br \/>\nThe economic case for investment in health<br \/>\nis strong. Investing in health generates cost-<br \/>\neffective health outcomes and economic,<br \/>\nsocial and environmental benefits. The<br \/>\nhealth sector\u2019s call on government to invest<br \/>\nin health will make this change happen. We<br \/>\nneed to give this message loudly.<br \/>\nFor example, current evidence suggests<br \/>\nthat investment in reproductive, maternal<br \/>\nand child health has a potential return of<br \/>\nmore than US$\u00a0 20 for every dollar spent.<br \/>\nThe argument for investing in the best-buy<br \/>\ninterventions is equally clear for addressing<br \/>\nnoncommunicable diseases (NCDs).<br \/>\nCurrent investments in health and public<br \/>\nhealth are not sufficient. We need to invest<br \/>\nmore. It is alarming to see that, between 2007<br \/>\nand 2011, the health share of public spending<br \/>\nfell in 24 countries in Europe.By tapping into<br \/>\nnew sources,improving efficiencies and giving<br \/>\nhigh priority to health, all countries can find<br \/>\nways to raise sufficient funds for health.<br \/>\nAlso, many countries are applying the life-<br \/>\ncourse approach in developing their na-<br \/>\ntional policies or improving collaboration<br \/>\nbetween sectors, which is a key strategic<br \/>\ndirection of Health 2020.<br \/>\nOn 25 September, world leaders gathered<br \/>\nat the United Nations summit to adopt the<br \/>\nAgenda for Sustainable Development, to<br \/>\nend poverty by 2030. The Agenda has uni-<br \/>\nversal goals that will apply to every nation\u00a0\u2013<br \/>\nnot just to developing countries. Among<br \/>\nthe 17 Sustainable Development Goals, the<br \/>\none for health is central. It aims to \u201censure<br \/>\nhealthy lives and promote well-being for all<br \/>\nat all ages\u201d. There is increasing acceptance<br \/>\nthat the new health goal must also aim to<br \/>\nachieve universal health coverage in every<br \/>\ncommunity, in every country of the world.<br \/>\nThe formulation of the health goal is fully<br \/>\naligned with Health 2020.<br \/>\nFocusing solely on the health goal would be<br \/>\na missed opportunity. All the Sustainable<br \/>\nDevelopment Goals will influence health,<br \/>\nbecause they all address the determinants<br \/>\nof health.The 2030 Agenda will link differ-<br \/>\nent dimensions of development\u00a0\u2013 including<br \/>\nhealth\u00a0\u2013 to the environment, to prosperity<br \/>\nand to all actions and policies that people<br \/>\nneed.<br \/>\nNow we have a historic political respon-<br \/>\nsibility to pursue the integration of health<br \/>\nand well-being into each and every goal.We<br \/>\nhave the opportunity to put into practice<br \/>\nthe whole-of-government and whole-of-<br \/>\nsociety approaches to which we subscribed<br \/>\nthrough Health 2020.<br \/>\nBetter health for Europe: more equitable<br \/>\nand sustainable\u00a0\u2013 that is what we work for.<br \/>\nQ. At present, there is an opposition to<br \/>\nvaccination in Latvia. The situation is<br \/>\npretty similar in other European coun-<br \/>\ntries. What can the WHO Regional Of-<br \/>\nfice do in order to promote immunization?<br \/>\nVaccination is one of the most cost-effective<br \/>\nhealth interventions available, saving mil-<br \/>\nlions of people from illness, disability and<br \/>\ndeath each year. Vaccines protect against<br \/>\nmore than 20 serious diseases.<br \/>\nAlthough the WHO European Region<br \/>\nhas made good progress in protecting more<br \/>\npeople, vaccine-preventable diseases still<br \/>\nchallenge Europe\u2019s public health and con-<br \/>\ntinue to burden our Member States. The<br \/>\nloss of a child from diphtheria, the deaths<br \/>\nof children from measles complications,<br \/>\nalongside thousands of cases of measles,<br \/>\nrepresent solemn reminders of unfinished<br \/>\nbusiness. Accepting the status quo is not an<br \/>\noption.<br \/>\nOur goal is to reach and maintain high levels<br \/>\nof immunization, particularly in vulnerable<br \/>\ngroups, at the appropriate ages and recom-<br \/>\nmended doses. To achieve this goal, WHO\/<br \/>\nEurope works with Member States, interna-<br \/>\ntional organizations and bilateral agencies to<br \/>\nhelp countries strengthen their programmes<br \/>\nfor the control of infectious diseases. Cur-<br \/>\nrent major initiatives include: supporting<br \/>\ncommunication capacity of national immu-<br \/>\nnization programmes; introducing new and<br \/>\nunderused vaccines; eliminating measles and<br \/>\nrubella and maintaining the poliomyelitis-<br \/>\nfree status of the European Region.<br \/>\nIn adopting the European Vaccine Action<br \/>\nPlan, our Member States committed them-<br \/>\nselves to eliminating measles and rubella by<br \/>\n2015.<br \/>\nWhile many countries are on track to do<br \/>\nthis by the end of this year, the regional<br \/>\ngoal continues to elude us,owing to the lack<br \/>\nof steadfast political commitment in some<br \/>\ncountries. We need public health leaders to<br \/>\nstand by your commitments to eliminate<br \/>\nmeasles and rubella.<br \/>\nThere is no stronger reminder of the need<br \/>\nfor vigilance than the return of polio.The re-<br \/>\nport of two cases in Ukraine, in August this<br \/>\nyear, is alarming, particularly given the large<br \/>\npockets of susceptible populations who could<br \/>\nbe exposed to this crippling, deadly disease.<br \/>\nIt is imperative that Ukraine and all Euro-<br \/>\npean countries continue to mitigate the risks<br \/>\nposed by polio by maintaining high immuni-<br \/>\nzation coverage and surveillance.<br \/>\nIn the 21st<br \/>\ncentury, every child has the right<br \/>\nto live free from vaccine-preventable dis-<br \/>\neases. Strengthening immunization is vital.<br \/>\nWHO\/Europe leads and coordinates Euro-<br \/>\npean Immunization Week (EIW). Since its<br \/>\nestablishment 10 years ago, EIW has served<br \/>\nas a flexible platform for Member States in<br \/>\nthe European Region to mobilize support for<br \/>\nimmunization. From its humble beginning<br \/>\nin 2005 with eight pilot countries, EIW ex-<br \/>\npanded each year to become a truly Region-<br \/>\nwide campaign encompassing all 53 Member<br \/>\nStates. Together with Immunization Week in<br \/>\nthe Americas,EIW was a forerunner of World<br \/>\nImmunization Week, established in 2012.<br \/>\nRegional and national partners,including the<br \/>\nUnited Nations Children\u2019s Fund (UNICEF)<br \/>\nand the European Centre for Disease Pre-<br \/>\nvention and Control (ECDC), support im-<br \/>\nplementation. EIW also benefits from high-<br \/>\nlevel support at the national level, including<br \/>\nministers, ambassadors, first ladies and other<br \/>\ndistinguished supporters. At the regional lev-<br \/>\nel, the initiative has the support of Her Royal<br \/>\nHighness Crown Princess of Denmark, who<br \/>\nis WHO\/Europe\u2019s patron. In April this year,<br \/>\nwe celebrated the tenth anniversary of the<br \/>\nEIW initiative throughout the Region.<br \/>\nThere is still a lot to be done in this area\u00a0\u2013 our<br \/>\nvision is a European Region free of vaccine-<br \/>\npreventable diseases. We need Latvia\u2019s full<br \/>\nsupport and commitment in reaching this goal.<br \/>\nQ. In the past two years, Latvia has made<br \/>\ngood progress in adopting a range of to-<br \/>\nbacco control regulatory legal acts. In<br \/>\nLatvia smoking is absolutely prohibited<br \/>\nin public facilities, premises of central and<br \/>\nlocal government institutions, work plac-<br \/>\nes, and elsewhere where it can harm other<br \/>\npeople\u2019s health. How would you evaluate<br \/>\nour achievement and how could we attain<br \/>\nthis in entire Europe?<br \/>\nYou are right: Latvia is doing well in tobac-<br \/>\nco control. The country ratified the WHO<br \/>\nFCTC in 2005 and took a number of legally<br \/>\nbinding obligations in tobacco control,from<br \/>\nsmoke-free public places, high taxes on to-<br \/>\nbacco products, banning tobacco advertis-<br \/>\ning to eliminating illicit trade in tobacco<br \/>\nproducts. Latvia is among only 33 countries<br \/>\nin the world that have sufficiently high tax<br \/>\nrates on tobacco, which are among the most<br \/>\neffective tools in reducing consumption.<br \/>\nHowever, a lot more needs to be done. Al-<br \/>\nthough the smoking among the adult popula-<br \/>\ntion has gone down in recent years, 30% of<br \/>\nLatvian adults smoke and this is slightly high-<br \/>\ner than in the WHO European Region in av-<br \/>\nerage (28%). Over 17% of female and 45% of<br \/>\nmale adult population smokes in Latvia\u00ad.<br \/>\nMore needs to be done in stopping young<br \/>\npeople to become addicted to tobacco and<br \/>\nstart the use of tobacco at an early age. Data<br \/>\non the current situation is grim: 70% of the<br \/>\nboys in Latvia initiated smoking at the age<br \/>\nof 15 years or younger (in comparison, in<br \/>\nUK and Ireland, it is around 30%); up to<br \/>\n72% of the girls in Latvia started smoking at<br \/>\nthe age of 15 years or younger (in compari-<br \/>\nson, in UK and Ireland, it is around 40%).<br \/>\nThe Region as a whole is striving towards<br \/>\nmaking tobacco a thing of the past. Last<br \/>\nweek, WHO Regional Committee for Eu-<br \/>\nrope\u00a0\u2013 Region\u2019s governing body\u00a0\u2013 adopted a<br \/>\nroadmap for tobacco control, setting an am-<br \/>\nbitious goal of full implementation of the<br \/>\nFCTC and the voluntary global target to<br \/>\nreduce tobacco use by 30% by 2025. We are<br \/>\ngrateful to Latvia for its support in adopting<br \/>\nthis roadmap and count on its support in its<br \/>\nimplementation in the coming years.<br \/>\nTobacco smoking among adults continues<br \/>\nto decline in the Region. Nevertheless, we<br \/>\nremain the region with the highest overall<br \/>\nrate of adult smoking.<br \/>\nIn the year 2000, 250 million adult people<br \/>\nin Europe smoked,in 2015,200 million and<br \/>\nit is projected that in 10 years\u2019time, in 2025,<br \/>\n180 million will continue to smoke. As of<br \/>\n2015, Europe has the highest number of its<br \/>\npeople smoking, 28%, in the world. Glob-<br \/>\nally, being born male has been the highest<br \/>\npredictor of smoking. However, European<br \/>\nwomen are smoking alarmingly more than<br \/>\nany other women around the globe.<br \/>\n19% of European adult women smoke and<br \/>\nthis number will continue to rise in the<br \/>\ncoming years while smoking among men is<br \/>\nstabilizing or going down.As a consequence<br \/>\nof women smoking like men in some coun-<br \/>\ntries, the breast cancer is not any more the<br \/>\nbiggest killer but the lung cancer is. The<br \/>\nchange in the rates of incidence and mor-<br \/>\ntality for lung cancer can be attributed to<br \/>\nsmoking prevalence amongst females.<br \/>\nAs a result of high levels of smoking, 16% of<br \/>\nEuropeans die as a result of a tobacco related<br \/>\ndisease while the global average is lower,12%.<br \/>\nAgainst this background, it is clear that Eu-<br \/>\nrope could and should do more to save health<br \/>\nand life of Europeans.We know what works;<br \/>\nwe have an international health treaty\u00a0\u2013 the<br \/>\nWHO Framework Convention on Tobacco<br \/>\nControl (FCTC), which is celebrating a de-<br \/>\ncade of action.At present,50\u00a0countries out of<br \/>\n53 in the WHO European Region have tak-<br \/>\nen the political commitment by ratifying this<br \/>\nTreaty but the actual implementation should<br \/>\nbe scaled up. Since last year, four additional<br \/>\ncountries in our Region have become parties<br \/>\nto the Protocol to Eliminate Illicit Trade in<br \/>\nTobacco Products. This is a great achieve-<br \/>\nment and we call on others to join.<br \/>\nSeveral countries in Europe are already<br \/>\nmoving towards becoming tobacco-free:<br \/>\nsuch as Ireland by 2025, Finland by 2040,<br \/>\nUK Scotland by 2034. Tobacco free coun-<br \/>\ntry is defined by less than 5% of adult<br \/>\npopulation\u00adsmokes. I am proud that our<br \/>\ncountries are taking global leadership in<br \/>\nplain packaging for tobacco products.<br \/>\nThe generation growing up now cannot<br \/>\ncomprehend that people used to smoke on<br \/>\nairplanes, buses, in restaurants or in offices.<br \/>\nThe achievements of the past 20 years show<br \/>\nthat the dream of a Europe where tobacco<br \/>\ncontrol has succeeded is not unrealistic.The<br \/>\ngains will be huge if tobacco control suc-<br \/>\nceeds, but there is hard work ahead. Gov-<br \/>\nernments must fully implement the mea-<br \/>\nsures in the WHO Framework Convention<br \/>\non Tobacco Control and work toward the<br \/>\nimplementation of a common goal: a Eu-<br \/>\nrope where tobacco is not a social norm.<br \/>\nBACK TO CONTENTS<br \/>\n86 87<br \/>\nGERMANY Infection DiseasesPublic Health Care<br \/>\nQ. Right now, there is quite an opposi-<br \/>\ntion to vaccination in Latvia. The situa-<br \/>\ntion is pretty similar in other European<br \/>\ncountries. There are excellent lecturers,<br \/>\nnice-looking books and YouTube files<br \/>\ndiscouraging people from vaccination<br \/>\nand explaining about the dangers of vac-<br \/>\ncination. What could the European phy-<br \/>\nsician do in order to present the informa-<br \/>\ntion on the need of immunization in an<br \/>\nequally attractive manner from the visual<br \/>\nand informative aspect?<br \/>\nYou are addressing a real problem in-<br \/>\ndeed. In our European countries, many<br \/>\nseem to have forgotten how life and<br \/>\ndeath was before vaccination and, disre-<br \/>\ngarding the immense progress medicine<br \/>\nhas brought to all of us, and particularly<br \/>\nto our children, they show something<br \/>\nlike a \u201cspoiled child\u201d attitude towards<br \/>\nvaccination.<br \/>\nI don\u2019t think that this is only a question of<br \/>\nnice booklets and lively internet pages\u00a0 \u2013<br \/>\nthe WHO for instance has produced an<br \/>\nabundance of both, and although it does<br \/>\noffer an important support, it is obviously<br \/>\nnot enough of what is needed. I think that<br \/>\nthe question relates much more to culture<br \/>\nand societal trends: as a reaction to the dif-<br \/>\nficulties of our industrial world and to the<br \/>\nthreats on health and the environment,<br \/>\npeople see nature, \u201cnatural\u201d medicines and<br \/>\nthe rejection of \u201cchemistry\u201d as the way to a<br \/>\n\u201csafer health\u201d.<br \/>\nSo what we have to do, as Doctors, and<br \/>\nthat\u2019s something I see as an ethical obliga-<br \/>\ntion for Doctors, is to convince, convince<br \/>\nand convince, without losing any opportu-<br \/>\nnity to discuss this with the patients, with<br \/>\nall the parents we see at our consultation.<br \/>\nWe don\u2019t have the right to give up!<br \/>\nQ.Maybe it is the time to have a single im-<br \/>\nmunization calendar in Europe?This issue<br \/>\nis becoming more and more topical due to<br \/>\nthe increasing labour mobility in Europe.<br \/>\nChildren are moving along with their par-<br \/>\nents. For example, a child is born in Lat-<br \/>\nvia, three months later it is taken to his or<br \/>\nher father to Ireland, and a year later the<br \/>\nparents come to Brussels to work there.<br \/>\nEach single country in Europe has its own<br \/>\nvaccination calendar, which is the reason<br \/>\nwhy many children do not get adequate<br \/>\nvaccination and immunization. To start<br \/>\nwith, perhaps we could declare as manda-<br \/>\ntory such vaccinations as against diphthe-<br \/>\nria, poliomyelitis, tetanus and some more<br \/>\nand these to be administered according to<br \/>\nstrictly defined time schedule all across<br \/>\nEurope, whereas the rest (rotavirus, Ger-<br \/>\nman measles, pneumococci) could be left<br \/>\nat the national level?<br \/>\nI understand the idea behind your question<br \/>\nvery well, but I am not sure I completely<br \/>\nshare your point of view.<br \/>\nWe live in a time when the European Union<br \/>\nis a concept questioned by quite a few peo-<br \/>\nple in all our countries, and it\u2019s obviously<br \/>\nnot a good time to go for mandatory uni-<br \/>\nformity; I\u2019d suggest to concentrate on the<br \/>\nresults\u00a0\u2013 request a good immunisation cov-<br \/>\nerage of the children at the end of school,<br \/>\nfor instance, and leave the \u201chow\u201d, the deci-<br \/>\nsions on the means to achieve this goal, in<br \/>\nthe hands of the Member States.<br \/>\nQ. Isn\u2019t it high time that we have a man-<br \/>\ndatory requirement to vaccinate all immi-<br \/>\ngrants from third countries, because their<br \/>\nearlier vaccination is unreliable? We are<br \/>\naware that many countries in Africa are<br \/>\nshort of vaccines, and people often have<br \/>\nfake vaccination documents.<br \/>\nI definitely think that it is an absolute ne-<br \/>\ncessity, and in fact a question of ethics and<br \/>\ndignity for all our European countries, to<br \/>\noffer proper healthcare to the refugees and<br \/>\nimmigrants now arriving in Europe.<br \/>\nI don\u2019t think though that we should make<br \/>\nany treatment mandatory in medicine, ex-<br \/>\ncept in very critical situations of health<br \/>\nemergencies, like epidemics for instance. In<br \/>\nall other circumstances, medical treatment<br \/>\n(and vaccination is one!) should be done<br \/>\nwith the consent of the patient: patients,<br \/>\nirrespective of their situation at the given<br \/>\nmoment, are partners of the health profes-<br \/>\nsionals for their own health!<br \/>\nQ. In Latvia, we conducted a survey<br \/>\namong medical doctors about vaccination.<br \/>\nThe question we asked was: do you im-<br \/>\nmunize and are you active in prescribing<br \/>\nimmunization against the flu for infants,<br \/>\npregnant women, patients with immuno-<br \/>\ndeficiency, and the answer was \u201cyes\u201d. An-<br \/>\nInterview with Dr. Jacques de Haller,<br \/>\nVice\u00a0President, President Elect 2016\u20132018<br \/>\n(Switzerland) of CPME<br \/>\nBy Dr. Peteris Apinis. September, 2015<br \/>\nJacques de Haller<br \/>\nother question was: have you immunized<br \/>\nyour own grandchildren, your daughter<br \/>\nor daughter-in-law who is expecting, in<br \/>\nmost cases the answer was \u201cno\u201d. Still an-<br \/>\nother question to doctors was: have you<br \/>\nimmunized yourself against the flu, and<br \/>\nthe answers were evasive\u00a0 \u2013 \u201ca couple of<br \/>\ntimes\u201d, \u201conce\u201d. The trust in vaccination<br \/>\nprogrammes has decreased in the doctors\u2019<br \/>\ncommunity. What can be done to recover<br \/>\nthe prestige of vaccination among medical<br \/>\nprofessionals?<br \/>\nThis is a terribly difficult question! We<br \/>\nhave the same situation in Switzerland,<br \/>\nand not only for immunization: some sur-<br \/>\ngical procedures show the same pattern, for<br \/>\ninstance.<br \/>\nI find it very positive that Doctors are in close<br \/>\ncontact with society,share its concerns,and are<br \/>\nnot isolated in an ivory tower, but at the same<br \/>\ntime Doctors should definitely remain in close<br \/>\ncontact with the academic world (permanent<br \/>\nmedical education is the point, here!), and be<br \/>\nmore willing and able to believe in what they<br \/>\nlearned. \u201cDo what I\u00a0say and not what I do\u201d is<br \/>\nnot an option for us,Doctors!<br \/>\nThe human-animal interface has devel-<br \/>\noped from ancient times till today into an<br \/>\narena with a complex pattern of interac-<br \/>\ntions, strongly affected by the constantly<br \/>\nevolving impact that humans have on<br \/>\ntheir local and global environments. Con-<br \/>\nsequently, many human pathogens have<br \/>\nevolved in the Neolithic revolution by<br \/>\ncrossing the animal-human species barrier<br \/>\nand subsequent adaptation to the newly<br \/>\ninvaded species. These include mumps<br \/>\nvirus (of the Paramyxoviridae family),<br \/>\nsmallpox virus, Corynebacterium diph-<br \/>\ntheriae, and Bordetella pertussis\u00a0 [1]. The<br \/>\nrespective animal hosts of origin of these<br \/>\npathogens, being domesticated, commen-<br \/>\nsal, or wild, have largely remained elusive.<br \/>\nWhile the phylogenetically closest spe-<br \/>\ncies of measles virus and smallpox virus<br \/>\nare rinderpest virus (infecting cattle), and<br \/>\ncamelpox or gerbilpox viruses, respec-<br \/>\ntively, it is unknown whether these animal<br \/>\nhost species were sources or recipients of<br \/>\nthese human pathogens. A recent pan-<br \/>\ndemic infectious disease outbreak fuelled<br \/>\nby a complex mix of predisposing factors<br \/>\nin our modern society was caused by the<br \/>\nemergence of HIV\/AIDS in Africa some<br \/>\n30 years ago. Today, the virus claims more<br \/>\nthan one million lives each year, with more<br \/>\nthan 20 million deadly victims in total<br \/>\nsince its emergence.<br \/>\nFortunately, the ever-increasing range of<br \/>\ninfectious diseases is largely paralleled by<br \/>\nthe implementation of an almost equally<br \/>\ncomplex mix of intervention strategies.<br \/>\nThe latter includes the coordinated and<br \/>\ntimely use of the achievements of medi-<br \/>\ncal, molecular, mathematical, social, and<br \/>\nother sciences. In the past decade, this has<br \/>\nresulted in the timely identification of the<br \/>\nSARS coronavirus, allowing concerted<br \/>\npublic health efforts to successfully control<br \/>\nthe emerging epidemic before the newly<br \/>\nintroduced pathogen could cause a full<br \/>\nblown pandemic. Although this will prove<br \/>\nmuch more difficult for more transmissible<br \/>\npathogens, as was the case for the latest<br \/>\ninfluenza pandemic of 2009, the SARS<br \/>\nepisode is unique in our recorded history.<br \/>\nAmong other most successful achieve-<br \/>\nments of modern medicine is the eradica-<br \/>\ntion of two long-time plagues: smallpox<br \/>\nand rinderpest that have devastated human<br \/>\nand animal populations for many centu-<br \/>\nries. In both cases, a combination of well<br \/>\ncoordinated mass vaccination campaigns,<br \/>\nintensive surveillance, and case contain-<br \/>\nment, successfully brought these pathogens<br \/>\nto extinction, with last identified cases in<br \/>\n1977 and 2001, respectively [2]. Stimulated<br \/>\nby these successes, concerted public health<br \/>\nefforts for the eradication of measles and<br \/>\npolio are currently ongoing, which in prin-<br \/>\nciple should be considered feasible in the<br \/>\nnear future, however, with major obstacles<br \/>\nrather being of political nature than related<br \/>\nto technical feasibility.<br \/>\nAlthough these successful eradications<br \/>\nmay represent victories over infectious<br \/>\ndiseases, the dynamic nature of infectious<br \/>\npathogens, in particular due to their epi-<br \/>\ndemiological and evolutionary flexibility<br \/>\nand adaptability, call for caution. With the<br \/>\neradication of pathogens and the waning<br \/>\nof immunity that had characterized ani-<br \/>\nmal and human populations for millennia,<br \/>\nwe are facing new challenges by creating<br \/>\nniches for colonization by related patho-<br \/>\ngens lurking in the animal world. Mon-<br \/>\nkeypox virus may be considered a loom-<br \/>\ning threat at the global human-animal<br \/>\ninterface, which one day could fully adapt<br \/>\nto more efficient human-to-human trans-<br \/>\nmission and fill the niche left empty by the<br \/>\neradicated smallpox virus. Similar threats<br \/>\nto animals and humans may come from<br \/>\nFrom Zoonosis to Pandemic<br \/>\nA.D.M.E. Osterhaus<br \/>\nBACK TO CONTENTS<br \/>\n88 89<br \/>\nRefugees and Health CareInfection Diseases GERMANY<br \/>\n\u00adanimal morbilliviruses\u00adafter the eradica-<br \/>\ntion of rinderpest or the future eradication<br \/>\nof measles [3].<br \/>\nUnexpected virus threats continue to<br \/>\nemerge, as is painfully demonstrated by the<br \/>\nincreasing number of human MERS coro-<br \/>\nnavirus (MERS-CoV) infections, partly<br \/>\ndue to increase in nosocomial transmis-<br \/>\nsion, but also because of ongoing transmis-<br \/>\nsion from dromedary camels to humans.<br \/>\nThe most prominent mode of camel-to-<br \/>\nhuman transmission is probably through<br \/>\nhuman contacts with respiratory excreta<br \/>\nalthough transmission via milk or urine<br \/>\ncannot be ruled out. An important break-<br \/>\nthrough was the identification of the re-<br \/>\nceptor of the virus in humans and animals,<br \/>\nwhich already proved helpful in identifying<br \/>\nanimal species susceptible to MERS-CoV<br \/>\ninfection and may further help in identi-<br \/>\nfying intervention strategies. An attractive<br \/>\noption would be to develop a vaccine for<br \/>\ndromedary camels and tackle the problem<br \/>\nat the source.<br \/>\nOur new era characterized by a real explo-<br \/>\nsion of novel molecular technology leads to<br \/>\nthe discovery of an avalanche of hitherto<br \/>\nunknown human and animal pathogens,<br \/>\nsome of which are candidates to fill newly<br \/>\nemerging niches at the modern human\u2013<br \/>\nanimal interface. For instance, in 2013, we<br \/>\nexamined sick harbour seals that had de-<br \/>\nveloped neurological signs. The seals were<br \/>\nsuffering from meningo-encephalitis of an<br \/>\nunknown cause. After thorough examina-<br \/>\ntion, a novel parvovirus was discovered<br \/>\nthat resembles the human B19 parvovirus<br \/>\nwhich among other manifestations has<br \/>\nbeen associated with neurological disease<br \/>\nin children. The human B19 parvovirus<br \/>\nhad also been associated with meningo-<br \/>\nencephalitis, but it was never demon-<br \/>\nstrated before that the virus can indeed<br \/>\nenter the brain tissue. By showing that<br \/>\nthe newly discovered seal B19-like parvo-<br \/>\nvirus is indeed present in brain tissue and<br \/>\ndirectly linked with neurological disease,<br \/>\nwe provide evidence that infection with<br \/>\nthis group of viruses may cause meningo-<br \/>\nencephalitis in animals and most probably<br \/>\nalso in humans F [4].<br \/>\nAnother group of infectious agents that<br \/>\ncontinues to cross animal-human species<br \/>\nbarriers consists of influenza A viruses.<br \/>\nIn the framework of several US and EU<br \/>\nfunded projects, the minimal determi-<br \/>\nnants of H5N1 transmission through air<br \/>\nwere identified: only a handful of amino<br \/>\nacid substitutions suffice for avian H5N1<br \/>\nvirus to become airborne in mammals,<br \/>\nand these are associated with three traits:<br \/>\nefficient binding to human type recep-<br \/>\ntors, increased stability of the hemag-<br \/>\nglutinin, and increased polymerase activ-<br \/>\nity in mammalian cells. In line with the<br \/>\nH5N1 research, similar experiments were<br \/>\nconducted with avian H7N9 virus, which<br \/>\nemerged in spring 2013. This virus was<br \/>\nfound to already display certain traits of<br \/>\nairborne H5N1. The wild type H7N9,<br \/>\nwithout any experimental modifications,<br \/>\nis indeed already airborne transmissible in<br \/>\nferrets, though not very efficiently\u00a0[5]. It<br \/>\nis suspected that it lacks sufficient hem-<br \/>\nagglutinin stability to be efficiently trans-<br \/>\nmissible, and needs to reduce binding to<br \/>\navian receptors.<br \/>\nIn conclusion, rather than investing in<br \/>\ntrying to influence the complex mix of<br \/>\npredisposing factors of emergence at the<br \/>\nhuman\u2013animal interface, which are largely<br \/>\nrelated to human behavioural issues, in-<br \/>\nvestment in newly emerging technologies<br \/>\nand intervention strategies may provide us<br \/>\nwith the tools to prevent or limit disasters<br \/>\ncaused by emerging infections. This will<br \/>\nnot only allow us to win major battles, but<br \/>\nalso to limit the impact of the apparently<br \/>\nnever ending war between mankind and<br \/>\nits relentlessly emerging microbial foes.<br \/>\nWe should do this in a multidisciplinary<br \/>\nOne Health approach. After all, emerg-<br \/>\ning and re-emerging infectious diseases<br \/>\nclearly demonstrate that human, animal<br \/>\nand ecosystem health are inextricably<br \/>\nlinked. It is therefore good to see that new<br \/>\nOne Health initiatives are taken, and in<br \/>\nthis context I would like to highlight the<br \/>\nnewly founded One Health Platform.This<br \/>\ninternational foundation brings together<br \/>\nkey opinion leaders of the One Health<br \/>\ntopic and provides them with a framework<br \/>\nfor information-sharing, cooperation and<br \/>\nawareness raising activities.<br \/>\nReferences<br \/>\n1.\t Wolfe ND. Origins of major human infectious<br \/>\ndiseases; Nature May 2007; 447.<br \/>\n2.\t Normile D. Rinderpest, Deadly for Cattle, Joins<br \/>\nSmallpox as a Vanquished Disease; Science Oc-<br \/>\ntober 2010; Vol 330 22.<br \/>\n3.\t de Swart R et al. Rinderpest eradication: lessons<br \/>\nfor measles eradication? j.coviro 2012.<br \/>\n4.\t Bodewes R et al. Novel B19-like parvovirus in<br \/>\nthe brain of a harbor seal; PLoS One. 2013 Nov<br \/>\n5;8(11)<br \/>\n5.\t Richard M et al. Limited airborne transmission<br \/>\nof H7N9 influenza A virus between ferrets; Na-<br \/>\nture. 2013 Sep 26;501(7468):560-3.<br \/>\nProf. A.D.M.E. Osterhaus,<br \/>\nDirector Research Centre for<br \/>\nEmerging Infections and Zoonoses<br \/>\n(RIZ), Hannover, Germany<br \/>\nE-mail: albert.osterhaus@tiho-hannover.de<br \/>\nAuthors\u2019 foreword<br \/>\nTruth is \u201cthe first casualty of war\u201d[1]. Many<br \/>\nrefugees come from war zones, and there is<br \/>\nlittle independent and even less empirical<br \/>\nresearch into the emerging refugee situation<br \/>\nin Europe. The authors strongly feel that<br \/>\navailable data should be presented without<br \/>\nbias so that readers may make their own<br \/>\njudgment.<br \/>\nFirst and foremost, the authors would like<br \/>\nto applaud the countless volunteers includ-<br \/>\ning health professionals providing assis-<br \/>\ntance to refugees across Europe and beyond.<br \/>\nMany are going above and beyond the call<br \/>\nof their professional duty to provide health-<br \/>\ncare to refugees. The main purpose of this<br \/>\narticle is to describe the current refugee cri-<br \/>\nsis. However, those providing this valuable<br \/>\nassistance should be recognized.<br \/>\nIntroduction<br \/>\nEach and every day, many individuals leave<br \/>\ntheir home countries, where instability, re-<br \/>\npression, terrorism, forced labor, poverty<br \/>\nand civil wars pose a threat to their lives and<br \/>\ntheir families. Current instability in parts of<br \/>\nthe Middle East, Northern and Sub-Saha-<br \/>\nran Africa is driving the biggest movement<br \/>\nof refugees across Europe since the Balkan<br \/>\nwars in the 1990s [2, 3, 4].<br \/>\nUnder the UN 1951 Convention and Pro-<br \/>\ntocol Relating to the Status of Refugees,<br \/>\na refugee is defined as an individual who<br \/>\n\u201c&#8230;owing to a well-founded fear of being<br \/>\npersecuted for reasons of race, religion, na-<br \/>\ntionality, membership of a particular social<br \/>\ngroup or political opinion, is outside the<br \/>\ncountry of his nationality, and is unable to,<br \/>\nor owing to such fear, is unwilling to avail<br \/>\nhimself of the protection of that coun-<br \/>\ntry\u201d\u00a0[5]. Refugee and asylum seeker are two<br \/>\ndistinct legally defined terms often used as<br \/>\nsynonyms in public and varying between<br \/>\njurisdictions [6]. This article focuses exclu-<br \/>\nsively on health and, for this reason, will<br \/>\nnot explore this legal nuance; therefore, the<br \/>\nterms are used synonymously unless other-<br \/>\nwise stated.<br \/>\nThe current crisis began in the wake of the<br \/>\nArab Spring when border crossings began to<br \/>\nrise in 2011. In addition, refugees originat-<br \/>\ning in both Northern and Sub-Saharan Af-<br \/>\nrica who had previously migrated to Libya<br \/>\nbegan to flee the unrest of the post-Qaddafi<br \/>\nera [4]. However, numbers have increased<br \/>\nsharply in 2015.The latest data, gathered in<br \/>\nSeptember 2015, indicate a total of 473,887<br \/>\nmen, women and children have arrived in<br \/>\nEurope by sea. Just under 40% were from<br \/>\nSyria, fleeing the country\u00b4s civil war and the<br \/>\nthreat posed by the self-styled Islamic State<br \/>\n(IS). In 2014, between 25-33% of those ar-<br \/>\nriving by sea were from Syria [2].<br \/>\nTurkey has an open door policy granting<br \/>\n\u201ctemporary protection status\u201d to every Syr-<br \/>\nian fleeing the conflict. Currently, Turkey<br \/>\nhosts the largest number of refugees in the<br \/>\nworld, with around 2 million people, while<br \/>\nLebanon has the highest quota of refugees<br \/>\nper inhabitant [7,8].According to UN High<br \/>\nCommission for Refugees (UNHCR), it<br \/>\nis estimated that Lebanon will have more<br \/>\nthan 1.8 million refugees and asylum seek-<br \/>\ners by the end of 2015 [9]. This condition<br \/>\nhas become a severe economic challenge for<br \/>\nthese countries\u2019 economies. Approximately<br \/>\n260,000 refugees are located in refugee<br \/>\ncamps,while the remaining live freely in the<br \/>\ncities [10]. The plight of children displaced<br \/>\nby the Syrian conflict is particularly dire;<br \/>\nMalta and Italy alone have received 10,000<br \/>\nseparated or unaccompanied children this<br \/>\nyear [11].<br \/>\nRefugees and migrants typically use one of<br \/>\nseven routes to reach Europe [7]:<br \/>\n\u2022\t Western African<br \/>\n\u2022\t Black Sea<br \/>\n\u2022\t Eastern borders<br \/>\n\u2022\t Western Mediterranean<br \/>\n\u2022\t Central Mediterranean<br \/>\n\u2022\t Eastern Mediterranean<br \/>\n\u2022\t Western Balkan<br \/>\nIn 2015, the Central Mediterranean, East-<br \/>\nern Mediterranean and Western Balkan<br \/>\nroute are most commonly used. Land bor-<br \/>\nders within the Western Balkan region were<br \/>\nthe main entry points for refugees with the<br \/>\nHungarian-Serbian border being the most<br \/>\nfrequently crossed border in the region. Mi-<br \/>\ngrants entering Europe through this route<br \/>\ninclude Western Balkan nationals and Syr-<br \/>\nians, followed by Afghans, Iraqis and Paki-<br \/>\nstanis [12]. Another highly popular route is<br \/>\nthrough Turkey, over the Eastern Aegean<br \/>\nSea to the Greek islands. Refugees from<br \/>\nSyria, Afghanistan, Iraq, Pakistan and Pal-<br \/>\nestine, amongst others, often use this route.<br \/>\nThey may arrive in Turkey by land or ferry<br \/>\nand continue on their way to Greece on car-<br \/>\ngo ships or inflatable boats [7].The number<br \/>\nof asylum seekers arriving in Greece each<br \/>\nday typically reaches around 5000, with<br \/>\npeaks of up to 10,000 [8].<br \/>\nCrossing the desert<br \/>\nFor Sub-Saharan African nationals, the<br \/>\nCentral Mediterranean route is a primary<br \/>\npoint of entry into Europe. Little data are<br \/>\navailable describing events in the Saharan<br \/>\ndesert.The United Nations Office on Drugs<br \/>\nand Crime (UNDOC) reports \u201conly\u201d 1691<br \/>\nconfirmed deaths in the desert; however,<br \/>\nit has been suggested that these numbers<br \/>\nsignificantly underestimate the number of<br \/>\nthose killed with actual numbers at least<br \/>\nthree times higher [13].<br \/>\nRefugees are not only at risk due to heat<br \/>\nstroke,thirst or starvation,but also face oth-<br \/>\ner dangers. According to UNDOC, many<br \/>\nHealth and Asylum Seekers in Europe<br \/>\nBACK TO CONTENTS<br \/>\n90 91<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\npaid a ransom. However, it is hard to verify<br \/>\nthis information. In a 2013 report, Reisen<br \/>\net al. that there have been an estimated<br \/>\n25,000-30,000 victims of Sinai trafficking<br \/>\nwith about 622 million USD in ransom<br \/>\ncollected [17]. While the Egyptian govern-<br \/>\nment\u2019s efforts have been successful in reduc-<br \/>\ning these crimes, exploitation of vulnerable<br \/>\nrefugees may have simply shifted to other<br \/>\nlawless zones.<br \/>\nCrossing the Mediterranean<br \/>\nAlmost daily, powerful photos are emerging<br \/>\nof refugees struggling to cross the Mediter-<br \/>\nranean \u2013 and in some cases, losing their lives<br \/>\nin search of a better future. In 2015, an esti-<br \/>\nmated 2,812 people have died crossing the<br \/>\nMediterranean Sea to date \u2013 an average of<br \/>\neight fatalities per day [18].The Internation-<br \/>\nal Organization for Migration estimates that<br \/>\nabout 75% of all refugee deaths worldwide<br \/>\nare occurring in the Mediterranean [19].<br \/>\nMany human smuggling networks operate<br \/>\nfrom the practically failed state of Libya,<br \/>\nsmuggling migrants mainly from Gambia,<br \/>\nSenegal, Somalia, Syria, Eritrea, Ethio-<br \/>\npia, Mali and Nigeria on wooden fishing<br \/>\nboats or inflatable boats with no naviga-<br \/>\ntion capacities and engines which often fail.<br \/>\nUsually a distress call is sent to the Italian<br \/>\nauthorities about 6-7 hours after departure<br \/>\nfrom the Libyan coast [7].<br \/>\nArriving in Europe<br \/>\nAccording to the International Organisa-<br \/>\ntion for Immigration, out of 430,000 refu-<br \/>\ngees and migrants who have reached West-<br \/>\nern Europe since the beginning of 2015,<br \/>\n390,000 have passed from Greek territory.<br \/>\nDaily, more than 4000 refugees set foot on<br \/>\nthe island of Lesbos having traveled across<br \/>\non small boats from the Turkish coast. Most<br \/>\nrefugees continue their journey via main-<br \/>\nland Greece, Macedonia, Serbia and Hun-<br \/>\ngary [20].<br \/>\nGermany and other neighboring Western<br \/>\nEuropean countries are the primary desti-<br \/>\nnations for refugees. In absolute numbers<br \/>\nGermany has admitted most refugees of all<br \/>\nEU countries, resulting in multiple health-<br \/>\ncare challenges [21].<br \/>\nHealth of refugees<br \/>\nFor most refugees, the journey to Europe is<br \/>\nfraught with a multitude of health threats,<br \/>\nalthough it is a common misconception<br \/>\nthat refugees themselves constitute a sig-<br \/>\nnificant health risk [22]. In this context,<br \/>\nit is also important to emphasize that<br \/>\nstigmatization of refugees is never justi-<br \/>\nfied and only risks creating or exacerbat-<br \/>\ning threats to health. Long and exhaust-<br \/>\ning travel under unsafe conditions and the<br \/>\ninterruption of health care can exacerbate<br \/>\nchronic diseases. Dangers specific to the<br \/>\nroutes and border-crossings pose health<br \/>\nthreats to young and healthy migrants<br \/>\nas well. People spend a long time hidden<br \/>\nin overcrowded trucks or boats. Injuries,<br \/>\nburns and dehydration are frequently oc-<br \/>\ncurring health problems. Traumatizing<br \/>\nexperiences in the country of origin or on<br \/>\nthe journey, and exposure to violence and<br \/>\nthe loss of family members, increase their<br \/>\nvulnerability to communicable and non-<br \/>\ncommunicable diseases. Children, preg-<br \/>\nnant women, elderly and immunocompro-<br \/>\nmised people are particularly susceptible to<br \/>\nhealth threats\u00a0[8].<br \/>\nFood insecurity among refugees also creates<br \/>\nmany additional potential health threats.<br \/>\nStarvation and malnutrition are a real-<br \/>\nity for many refugees [23, 24]. In addition,<br \/>\nrefugees may resort to trying to obtain food<br \/>\nwherever they can.In Germany,this has had<br \/>\ndisastrous consequences where more than<br \/>\nthirty refugees have become seriously ill and<br \/>\nat least one refugee has died after ingesting<br \/>\npoisonous mushrooms. It is believed that<br \/>\nthese mushrooms were consumed because<br \/>\nthey look similar to common edible mush-<br \/>\nroom in Syria [25, 26, 27].<br \/>\nInfectious Diseases<br \/>\nDue to poor hygiene conditions in transit<br \/>\nand in receiving facilities, diarrhea, acute re-<br \/>\nspiratory infections, skin infections, scabies<br \/>\nand head lice may occur [28, 29]. The sup-<br \/>\nply of safe water and food may be limited<br \/>\nduring the journey. Unsanitary conditions<br \/>\ncan often be found at border points and in<br \/>\nreceiving facilities, with a lack of safe drink-<br \/>\ning water, shower facilities and regular re-<br \/>\nmoval of waste. The result can be outbreaks<br \/>\nof food- and water-borne diseases such as<br \/>\nsalmonellosis, shigellosis, campylobacterio-<br \/>\nsis and hepatitis A [8].<br \/>\nCommunicable diseases are often associ-<br \/>\nated with poverty. An efficient health sys-<br \/>\ntem, good housing, hygiene, vaccinations<br \/>\nand clean water reduce the prevalence of<br \/>\ndiseases such as TB, measles, rubella, and<br \/>\nhepatitis.They still exist in the European re-<br \/>\ngion, independent of migration. The influx<br \/>\nof people from countries where infectious<br \/>\ndiseases are more prevalent can change the<br \/>\ndisease burden in Europe, although there is<br \/>\nno proven association between migration<br \/>\nand the importation of infectious diseases.<br \/>\nExperience shows that if cases of exotic in-<br \/>\nfections, such as the Ebola virus, occur in<br \/>\nEurope it affects regular travelers or health<br \/>\ncare workers rather than migrants [8].<br \/>\nOther infectious diseases such as scabies<br \/>\nhave also emerged as a public health chal-<br \/>\nlenge. In Germany, Hamburg, health au-<br \/>\nthorities declared a health emergency on<br \/>\nAugust 21st<br \/>\ndue to an outbreak of scabies<br \/>\nin an emergency shelter for newly arrived<br \/>\nasylum seekers. At the time, only topical<br \/>\nanti-scabies therapies were available within<br \/>\nGermany (Permethrin and Benzylben-<br \/>\nzoate) [30]. Ivermectin, an antifilarial on<br \/>\nWHO\u2019s list of essential medicines [31] and<br \/>\nthe de facto oral therapeutic standard for<br \/>\nscabies [32], is publicly available in France<br \/>\nbut only with indications for treatment of<br \/>\nstrongyloidiasis and elefantiasis not scabies<br \/>\n[33]. On September 2nd<br \/>\n, the Federal Minis-<br \/>\ntry of Health declared scabies a dangerous<br \/>\ndie in traffic accidents,overcrowded vehicles<br \/>\nor by simply falling off of a vehicle and be-<br \/>\ning left in the desert [13]. There are even<br \/>\nmore shocking reports of abuse, torture and<br \/>\nother crimes against refugees. Until 2013,<br \/>\nwhen the Egyptian Government reinstated<br \/>\nthe rule of law in the Sinai [14], many refu-<br \/>\ngees became victims of rape, torture \u2013 or<br \/>\neven homicide.<br \/>\nPhysicians for Human Rights-Israel report<br \/>\nthat 59% of asylum seekers treated at their<br \/>\nopen clinic report being chained and\/or<br \/>\nlocked up with 52% also reporting physical<br \/>\nabuse [15]. A CNN crew visiting the Sinai<br \/>\nreported that the morgue was packed with<br \/>\ndead corpses daily [16] with refugees being<br \/>\nabducted and tortured until their families<br \/>\nBACK TO CONTENTS<br \/>\n92 93<br \/>\nthat a person (migrant) will experience with<br \/>\ntime: \u201cfamily and friends, language, culture,<br \/>\nhomeland,loss of status,loss of contact with<br \/>\nthe ethnic group, and exposure to physical<br \/>\nrisks\u201d [46]. Reception in the intended des-<br \/>\ntination country can be very important for<br \/>\ncompletion of this grief process [46].<br \/>\nMcColl et al. defined some pre-migration<br \/>\nand post-migration adversities in the con-<br \/>\ntext of UK asylum applicants. Pre-migra-<br \/>\ntion adversities include war, imprisonment,<br \/>\ngenocide, physical or sexual violence, trau-<br \/>\nmatic bereavement, lack of healthcare, etc.,<br \/>\nwhile post-migration adversities are the<br \/>\n\u201cseven Ds\u201d: discrimination, detention, dis-<br \/>\npersal, destitution, denial of the right to<br \/>\nwork,denial of healthcare,delayed decisions<br \/>\non asylum applications [47].<br \/>\nIt is important to emphasize that the ma-<br \/>\njority of refugees and asylum seekers do not<br \/>\nsuffer from a psychiatric condition [47]. In<br \/>\nthis context, traumatic experiences should<br \/>\nbe addressed without pathologizing normal<br \/>\nhuman reactions [48].<br \/>\nA meta-analysis by Porter and Haslam found<br \/>\nthat,compared to non-refugees,refugees had<br \/>\nsomewhat poorer outcomes in psychopa-<br \/>\nthology measures. They also found that the<br \/>\nmental health outcomes are influenced by<br \/>\npostdisplacement conditions, and that refu-<br \/>\ngees who are living in institutional accom-<br \/>\nmodation, economically restricted, internally<br \/>\ndisplaced, persons who were repatriated, or<br \/>\nwhose initiating conflict was unresolved had<br \/>\nworse outcomes. Worse outcomes were also<br \/>\nfound in more educated, older, female, per-<br \/>\nsons with higher socioeconomic status and<br \/>\nrural residence before the migration [49].<br \/>\nStudies suggest that two thirds of refugees<br \/>\nexperience anxiety and\/or depression, and<br \/>\nhave a higher incidence of post traumatic<br \/>\nstress disorder, panic disorder and agora-<br \/>\nphobia, in addition to depression and anxi-<br \/>\nety [46]. Post traumatic stress disorder is<br \/>\nthe leading mental health condition among<br \/>\nrefugees and asylum seekers, probably con-<br \/>\nnected to the experiences in the country of<br \/>\norigin (persecution, conflicts, etc.) [46]. A<br \/>\nreview by Fazel et al.in 2005 found that ref-<br \/>\nugees placed in Western countries were 10<br \/>\ntimes more likely to have PTSD than the<br \/>\ngeneral population [50]. There is also a dif-<br \/>\nference between the group of migrants \u2013 for<br \/>\nexample, a Norwegian study found asylum<br \/>\nseekers to have higher rates of PTSD than<br \/>\nrefugees [51]<br \/>\nIn addition, asylum interviews are shown<br \/>\nto have a stressful effect on asylum seekers,<br \/>\nespecially when the asylum seekers were<br \/>\nalready traumatized [52]. Apart from the<br \/>\nprocedural difficulties in obtaining asylum,<br \/>\naccess to healthcare also poses a major chal-<br \/>\nlenge for many refugees.<br \/>\nUndocumented migrants, or the migrants<br \/>\nwithout legal status, face obstacles to receiv-<br \/>\ning adequate healthcare services \u2013 particu-<br \/>\nlarly mental health services \u2013 in destination<br \/>\ncountries. Many times healthcare access for<br \/>\nrefugees is limited to emergencies curbing ac-<br \/>\ncessibility to mental health services and there-<br \/>\nfore influences the overall health of refugees.<br \/>\nIt is important to protect and ensure ad-<br \/>\nequate treatment of persons who are already<br \/>\nsuffering of a severe mental disorder. This<br \/>\ngroup of refugees is particularly vulnerable<br \/>\nand can be considered neglected in complex<br \/>\nemergencies, such as conflicts [53].<br \/>\nSome countries provide mental health ser-<br \/>\nvices to the refugees who enter their borders<br \/>\n(e.g. temporary protection status in Turkey<br \/>\nincludes mental health services). However,<br \/>\nresource shortages limit these services to life-<br \/>\nthreatening emergencies in many places\u00ad.<br \/>\nWomen and LGBT Health<br \/>\nRefugee women face higher rates of ex-<br \/>\nposure to violence, sexual exploitation and<br \/>\nabuse than men [54].Risks increase on their<br \/>\njourney and can be exacerbated by lack of<br \/>\naccess to emergency sexual assault treat-<br \/>\nment and obstetrical care [55]. The stress<br \/>\nof the migratory process can also trigger or<br \/>\nintensify intimate partner violence [56, 57].<br \/>\nSexual violence, abuse, trafficking and rape<br \/>\nby smugglers, officials, policemen and male<br \/>\nrefugees are a common experience among<br \/>\nrefugee women. Some may be forced into<br \/>\nprostitution [58, 59, 60].The selling of Syr-<br \/>\nian brides has become a business in Turkey.<br \/>\nUnwanted pregnancies without access to<br \/>\nsafe abortions and venereal diseases without<br \/>\naccess to appropriate treatment may occur<br \/>\nas a result [61, 62].<br \/>\nIn July and August of 2015, 36160 Syrian<br \/>\nmales applied for asylum in the EU-28 only<br \/>\n10970 female Syrian refugees did so [63].<br \/>\nThis is in sharp contrast to the 1:1 ratio<br \/>\nworldwide. [64] It is reported that many<br \/>\nfamilies can only afford paying for one per-<br \/>\nson\u2019s trip and will send young healthy males<br \/>\nas a pilot, hoping for their female family<br \/>\nmembers to be allowed to join them later<br \/>\n[65]. However, it should not be neglected<br \/>\nfemale refugees are an even more vulnerable<br \/>\ngroup [66, 67].<br \/>\nIn Germany, emergency shelters are cur-<br \/>\nrently so overcrowded that males and fe-<br \/>\nmales share sleeping space in gyms, as well<br \/>\nas toilets and showers [66]. Even though<br \/>\nauthorities were not able to confirm, Ger-<br \/>\nman NGOs reported widespread cases of<br \/>\nrape and forced prostitution in an emer-<br \/>\ngency shelters for new arrivals in Gie\u00dfen,<br \/>\nHesse Germany [68].<br \/>\nAccording to a report from the German In-<br \/>\nstitute for Human Rights on refugees and<br \/>\ngender-specific violence,protection through<br \/>\n\u201crestraining and protection orders\u201dare avail-<br \/>\nable for refugees as well; however, refugees\u2019<br \/>\nchoice of accommodations and even move-<br \/>\nment is limited by law. In many cases, only<br \/>\nthe husband claimed reasons for asylum and<br \/>\nin that case under German law the partner\u2019s<br \/>\nasylum will depend on continued marriage.<br \/>\nLegally violent partners may be separated<br \/>\nto different accommodations even against a<br \/>\n\u00adcommunicable disease and authorized im-<br \/>\nportation of Ivermectin without prior mar-<br \/>\nketing approval [30].<br \/>\nThe prevalence of HIV is low among people<br \/>\nfrom the Middle East and Northern Africa<br \/>\n[8]. Most HIV cases in migrants are found<br \/>\nin Sub-Saharan African nationals. About<br \/>\n40% of HIV cases in Europe are migrants.<br \/>\nThere is also growing evidence that some<br \/>\nmigrant populations acquire HIV after ar-<br \/>\nriving in Europe [34]. Antiretroviral treat-<br \/>\nment can be interrupted for refugees liv-<br \/>\ning with HIV with potentially devastating<br \/>\nconsequences. In some European countries,<br \/>\nno HIV services are offered to people with<br \/>\nuncertain legal status [34].<br \/>\nThe majority of tuberculosis (TB) cases are<br \/>\ndetected in the native-born population in<br \/>\nEurope, with substantial variation across<br \/>\nEuropean countries. People with severe<br \/>\ncases of TB are often not fit for travel and<br \/>\ntherefore do not attempt the journey. TB is<br \/>\nnot easily transmissible and active disease<br \/>\noccurs only in a small proportion of those<br \/>\ninfected. However, crowded and humid<br \/>\nspaces such as those found in trucks and<br \/>\nships may facilitate the transmission of TB<br \/>\nwhen an infected person is present [8]. The<br \/>\noverall incidence is declining, while it is on<br \/>\nthe rise among migrants [34].<br \/>\nThe mass influx of refugees increases the<br \/>\nrisk of the reintroduction of vector-borne<br \/>\ndiseases such as Malaria, Leishmaniasis and<br \/>\nto the European region.Tajikistan and Tur-<br \/>\nkey are at particularly high risk at the mo-<br \/>\nment [8, 34, 35].<br \/>\nOutbreaks of measles, rubella and other<br \/>\nvaccine-preventable diseases can occur in<br \/>\nthe migrant population and spread to un-<br \/>\nvaccinated people of the receiving country.<br \/>\nThere is still a gap in vaccination coverage<br \/>\nin European countries due to refusal to<br \/>\nvaccinate. In migrants\u2019 countries of origin,<br \/>\naccess to vaccinations is often considerably<br \/>\nlower than in EU countries, creating condi-<br \/>\ntions under which outbreaks may emerge.<br \/>\nThe 2015 outbreak of measles in Berlin had<br \/>\noriginated within a group of asylum seekers<br \/>\nfrom Serbia and Bosnia and Herzegovina<br \/>\n[36, 8].<br \/>\nIn Turkey, registered refugees are provided<br \/>\ntemporary protection status and are then<br \/>\nplaced in provinces based on a national plan.<br \/>\nHowever, the rapidly increasing number of<br \/>\nrefugees has made execution of this plan dif-<br \/>\nficult and created new medical challenges.<br \/>\nAccording to an official field survey report<br \/>\nby AFAD in 2013, 26% of children in refu-<br \/>\ngee camps and 45% of children not living<br \/>\nin camps did not receive polio vaccination.<br \/>\nOne in three children in camps and 41% of<br \/>\nthe children out of the camps did not have<br \/>\nmeasles vaccination [37]. This situation in-<br \/>\ntroduced the risk of polio to a country which<br \/>\nwas polio-free for more than 15 years.There<br \/>\nhas been also a rise in other infectious dis-<br \/>\neases including measles,tuberculosis and cu-<br \/>\ntaneous leishmaniasis [38, 39].<br \/>\nMany developing countries experience a<br \/>\nhigh burden of hepatitis B cases. Incidence<br \/>\nis higher among migrants than among na-<br \/>\ntive populations in most European coun-<br \/>\ntries. Chronic infections are particularly<br \/>\nincreasing. In most cases, migrants acquired<br \/>\nthe virus in their countries of origin or from<br \/>\nmother-to-child transmission [34].<br \/>\nIn Lebanon, the sanitation conditions in<br \/>\nrefugee camps are very basic and a surge<br \/>\nof diarrheal diseases has been observed in<br \/>\n2014 by the epidemiologic surveillance unit<br \/>\nof the Lebanese Ministry of Public Health.<br \/>\nLebanon has seen an increase in the num-<br \/>\nber of reported tuberculosis, hepatitis A<br \/>\nand measles cases [40]. In addition, a vec-<br \/>\ntor borne disease, cutaneous leishmaniasis,<br \/>\nwhich was not present in Lebanon before,<br \/>\nhas made its appearance with 476 cases in<br \/>\n2014, all in Syrian Refugees.There is a con-<br \/>\ncern about the introduction of the sandfly<br \/>\nvector to Lebanon, but this has not been<br \/>\nproven with certainty yet. The community<br \/>\nphysicians have faced a major challenge in<br \/>\nmaking a timely diagnosis of Leishmaniasis,<br \/>\na condition they had not be accustomed to<br \/>\nevaluating and treating in the past[35]. Ma-<br \/>\njor education efforts for healthcare workers<br \/>\nthrough tertiary care and academic medi-<br \/>\ncal centers in Lebanon, are undertaken to<br \/>\nspread the knowledge about the disease.<br \/>\nNCDs<br \/>\nNoncommunicable diseases are a significant<br \/>\nproblem in the refugee population. Diabetes,<br \/>\ncardiovascular diseases, chronic lung diseases<br \/>\nand cancer are the most common of these.<br \/>\nThe exhausting and demanding circumstanc-<br \/>\nes of the journey often lead to exacerbations<br \/>\nof chronic diseases.A common characteristic<br \/>\nis that these conditions require regular and<br \/>\ncontinuous treatment. The supply of drugs<br \/>\nand the access to necessary procedures and<br \/>\ncare can be interrupted, resulting in poorer<br \/>\nhealth outcomes including unnecessary mor-<br \/>\nbidity and mortality [8, 41]. In the process<br \/>\nof uprooting and social marginalization, mi-<br \/>\ngrants may lose self-esteem and feel power-<br \/>\nless to manage chronic illness. The situation<br \/>\nis exacerbated by linguistic barriers and a real<br \/>\nor perceived inability to seek health care [42,<br \/>\n18]. For many refugees fleeing the Syrian<br \/>\ncivil war, access to non-communicable dis-<br \/>\nease management and prevention may have<br \/>\nbeen limited for years as the Syrian health<br \/>\ncare system has been \u201cshattered\u201d by the con-<br \/>\nflict with more than 75% of physicians hav-<br \/>\ning fled the country [43, 44]. Numerous re-<br \/>\nports have described attacks on health care<br \/>\nfacilities in clear violation of international<br \/>\nhumanitarian law [45].<br \/>\nMental Health<br \/>\nThe effect of migration on an individual<br \/>\nis pervasive \u2013 everything in person\u2019s life<br \/>\nchanges: diet, family, culture, social rela-<br \/>\ntions, status, etc [46]. Migratory experience<br \/>\nis essentially a psycho-social process of loss<br \/>\nand change, which can be labeled as a grief<br \/>\nprocess. This can be explained through a<br \/>\nmodel comprising of seven griefs of losses<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\nBACK TO CONTENTS<br \/>\n94 95<br \/>\nConclusion<br \/>\nPeople travel with their health profiles, val-<br \/>\nues, culture and beliefs. Health workers in<br \/>\nEurope and beyond need to be aware of this<br \/>\nand have the necessary knowledge to pro-<br \/>\nvide high quality care to refugees. Recipient<br \/>\ncountries must be prepared to be responsive<br \/>\nin the event of a crisis, so as to deliver basic<br \/>\nservices to migrants in recognition to their<br \/>\nbasic human rights [28].<br \/>\nLarge numbers of people moving between<br \/>\ncountries may have implications for the<br \/>\ncharacter and distribution of a country or<br \/>\nregion\u2019s disease burden. Acute conditions,<br \/>\nmany of them infectious disease, psychiat-<br \/>\nric illness or injuries sustained fleeing their<br \/>\nhome countries might be the most obvious.<br \/>\nMany refugee lack access to mental health-<br \/>\ncare and delayed treatment for mental<br \/>\nhealth problems may worsen refugees\u2019prog-<br \/>\nnosis. Attention must be given to persons<br \/>\nwith pre-existing psychiatric disorder as<br \/>\nwell as other vulnerable groups.<br \/>\nHowever, host countries themselves are also<br \/>\nimportant factors for refugees\u2019 health. Cul-<br \/>\ntural and language barriers can in worst case<br \/>\ncause innocent, yet deadly confusion. The<br \/>\nbasic rules of hygiene and sanitation are an<br \/>\nimportant factor for today\u2019s increased life<br \/>\nexpectancy [84], ensuring these basic rules<br \/>\nfor refugees should be of immediate concern.<br \/>\nHowever, we believe that after the acute<br \/>\nphase refugees and health care systems<br \/>\nwill adapt to each other and chronic con-<br \/>\nditions will set in. The social determinants<br \/>\nof health have been shown to be crucial for<br \/>\nhealth [85] and first and second generation<br \/>\nimmigrants face many challenges, amongst<br \/>\nthem often lower wages and less education<br \/>\n[86]. While today\u2019s situation may seems to<br \/>\nbe a crisis, it should not be forgotten that<br \/>\nrefugees health challenges will not end<br \/>\nwhen an asylum decision has been made.<br \/>\nLike with any other human being, health<br \/>\nis a lifelong process even setting the course<br \/>\nfor future generations. For this reason, it is<br \/>\ncritical that governments, national medical<br \/>\nassociations and health professionals ensure<br \/>\na sustained,timely and appropriate response<br \/>\nto the health implications of refugee crises<br \/>\n[87,\u00a088]. Refugee health is public health.<br \/>\nReferences<br \/>\n1.\t Snowden P. Introduction. In: Morel ED (ed.) Truth<br \/>\nand the War. London: National Labour Press Ltd;<br \/>\n1916. pp. VII \u2013 IX.<br \/>\n2.\t IOM: Latest Data on Europe Migrant Emergency [In-<br \/>\nternet].International Organization for Migration.2015<br \/>\n[cited 2015 Sep 27]. Available from: http:\/\/www.iom.<br \/>\nint\/news\/iom-latest-data-europe-migrant-emergency<br \/>\n3.\t BBC News. Migrant crisis: How can EU respond to<br \/>\ninflux? BBC News [Internet]. [cited 2015 Sep\u00a0 28].<br \/>\nAvailable from: http:\/\/www.bbc.com\/news\/world-<br \/>\neurope-34139348<br \/>\n4.\t CFR. Europe\u2019s Migration Crisis [Internet]. Council on<br \/>\nForeign Relations. [cited 2015 Sep 28]. Available from:<br \/>\nhttp:\/\/www.cfr.org\/migration\/europes-migration-<br \/>\ncrisis\/p32874<br \/>\n5.\t UNHCR. Convention and Protocol Relating to the<br \/>\nStatus of Refugees.United Nations High Commission-<br \/>\ner for Refugees. [Internet]. [cited 2015 Sep 29]. Avail-<br \/>\nable from: http:\/\/www.unhcr.org\/3b66c2aa10.html<br \/>\n6.\t UNESCO. Asylum Seeker. United Nations Educa-<br \/>\ntional, Scientific and Cultural Organization [Internet].<br \/>\n[cited 2015 Oct 1]. Available from: http:\/\/www.unesco.<br \/>\norg\/new\/en\/social-and-human-sciences\/themes\/inter-<br \/>\nnational-migration\/glossary\/asylum-seeker\/<br \/>\n7.\t Frontex. FRAN Quarterly. Quarter 1 January\u2013March<br \/>\n2015, 2015 Jun. [Internet]. Available from: http:\/\/<br \/>\nfrontex.europa.eu\/assets\/Publications\/Risk_Analysis\/<br \/>\nFRAN_Q1_2015.pdf<br \/>\n8.\t WHO\/Europe. Frequently asked questions on migra-<br \/>\ntion and health. World Health Organization. [Inter-<br \/>\nnet] [cited 2015 Sep 27]. Available from: http:\/\/www.<br \/>\neuro.who.int\/en\/health-topics\/health-determinants\/<br \/>\nmigration-and-health\/migrant-health-in-the-europe-<br \/>\nan-region\/frequently-asked-questions-on-migration-<br \/>\nand-health<br \/>\n9.\t UNHCR \u2013 Lebanon. United Nations High Com-<br \/>\nmissioner for Refugees. [Internet]. [cited 2015<br \/>\nSep 29]. Available from: http:\/\/www.unhcr.org\/<br \/>\npages\/49e486676.html<br \/>\n10.\t Suriye Raporlar\u0131 \u2013 AFAD | Afet ve Acil Durum<br \/>\nY\u00f6netimi Ba\u015fkanl\u0131\u011f\u0131 [Internet]. 2015 [cited 2015 Sep<br \/>\n27]. Available from: https:\/\/www.afad.gov.tr\/TR\/Ic-<br \/>\nerikDetay1.aspx?ID=16&#038;IcerikID=747<br \/>\n11.\t UNHCR 2015 UNHCR regional operations profile<br \/>\n\u2013 Europe | WORKING ENVIRONMENT. United<br \/>\nNations High Commissioner for Refugees. [Internet].<br \/>\n[cited 2015 Sep 27]. Available from: http:\/\/www.unhcr.<br \/>\norg\/pages\/4a02d9346.html<br \/>\n12.\t Frontex. Western Balkans Quarterly, Quarter 2 April-<br \/>\nJune 2015.<br \/>\n13.\t Ellis S, Niap\u00e9gu\u00e9 Cisse P, Imorou A-B, Vincent-Osa-<br \/>\nghae GN, Restoy E, Garsany J. The role of organized<br \/>\ncrime in the smuggling of migrants from West Africa<br \/>\nto the European Union.[Internet].United Nations Of-<br \/>\nfice on Drugs and Crime; 2011 May. Available from:<br \/>\nhttps:\/\/www.unodc.org\/documents\/human-traffick-<br \/>\ning\/Migrant-Smuggling\/Report_SOM_West_Af-<br \/>\nrica_EU.pdf<br \/>\n14.\t Human trafficking in the Sinai \u2013 Houses of torture.<br \/>\nEconomist [Internet]. 2013 Dec 5 [cited 2015 Sep<br \/>\n27]; Available from: http:\/\/www.economist.com\/blogs\/<br \/>\npomegranate\/2013\/12\/human-trafficking-sinai<br \/>\n15.\t A New PHR-Israel Report \u2013 Hostages, Torture, and<br \/>\nRape in the Desert: Findings from 284 Asylum Seekers<br \/>\nabout Atrocities in the Sinai [Internet]. Physicians for<br \/>\nHuman Rights-Israel; 2011 Feb.Available from: http:\/\/<br \/>\nwww.phr.org.il\/uploaded\/Phr-israel-Sinai-Report-<br \/>\nEnglish-23.2.2011.pdf<br \/>\n16.\t Pleitgen F, Fadel Fahmy M. Death in the desert:<br \/>\nTribesmen exploit battle to reach Israel. CNN.com<br \/>\n[Internet]. 2011 Nov 3 [cited 2015 Sep 27]; Available<br \/>\nfrom: http:\/\/www.cnn.com\/2011\/11\/02\/world\/meast\/<br \/>\negypt-refugees\/index.html<br \/>\n17.\t Van Reisen M, Estefanos M, Rijken C. The Human<br \/>\nTrafficking Cycle: Sinai and Beyond [Internet].Sellars-<br \/>\nShrestha S(ed.) 2013, Wolf Legal Publishers, Oister-<br \/>\nwijk. Available from: http:\/\/index.justice.gov.il\/Units\/<br \/>\nTrafficking\/MainDocs\/Small_HumanTrafficking-<br \/>\nSinai2-web-4.pdf<br \/>\n18.\t IOM. Latest Data on Europe Migrant Emergency [In-<br \/>\nternet].International Organization for Migration.2015<br \/>\n[cited 2015 Sep 27]. Available from: http:\/\/www.iom.<br \/>\nint\/news\/iom-latest-data-europe-migrant-emergency<br \/>\n19.\t Brian T, Laczko F. Counting Migrant Deaths: Chap-<br \/>\nter 1 An International Overview. In: Fatal Journeys\u00a0\u2013<br \/>\nCounting the Uncounted [Internet]. Geneva: Inter-<br \/>\nnational Organization for Migration; 2014. p. 15\u201343.<br \/>\nAvailable from: http:\/\/publications.iom.int\/bookstore\/<br \/>\nfree\/FatalJourneys_CountingtheUncounted.pdf<br \/>\n20.\t Behrakis BY. Sharp increase in migrant arrivals on<br \/>\nGreece\u2019s Lesbos island [Internet]. Reuters. 2015 [cited<br \/>\n2015 Sep 28]. Available from: http:\/\/www.reuters.<br \/>\ncom\/article\/2015\/09\/23\/us-europe-migrants-greece-<br \/>\nidUSKCN0RN12K20150923<br \/>\n21.\t Baeck J-P. Hygienem\u00e4ngel in Fl\u00fcchtlingsunterkunft:<br \/>\nKinder kriegen die Kr\u00e4tze. TAZ [Internet]. 2015 Jun<br \/>\n12 [cited 2015 Sep 27]; Available from: http:\/\/www.taz.<br \/>\nde\/!5203843\/<br \/>\n22.\t Gulland A. Refugees pose little health risk, says WHO.<br \/>\nBMJ [Internet].2015 Sep 8;351:h4808.Available from:<br \/>\nhttp:\/\/dx.doi.org\/10.1136\/bmj.h4808<br \/>\n23.\t RFI. Syrian refugees in Middle East face growing<br \/>\nhunger, WFP. RFI [Internet]. 2015 Sep 8 [cited 2015<br \/>\nSep 28]; Available from: http:\/\/www.english.rfi.fr\/<br \/>\nmiddle-east\/20150908-syrian-refugees-middle-east-<br \/>\nface-hunger-WFP<br \/>\n24.\t UNWFP. Syria Emergency | WFP | United Nations<br \/>\nWorld Food Programme \u2013 Fighting Hunger World-<br \/>\nwide [Internet]. World Food Programme. [cited 2015<br \/>\nSep 28]. Available from: https:\/\/www.wfp.org\/emer-<br \/>\ngencies\/syria<br \/>\n25.\t Migrants: Germany, 30 mushroom poisoning cases<br \/>\namong refugee. ANSA News [Internet]. 2015 Sep 21<br \/>\n[cited 2015 Sep 27]; Available from: http:\/\/www.cei.<br \/>\nint\/node\/1767\/19080<br \/>\n26.\t Teenage refugee dies after consuming poisonous<br \/>\nmushroom. Deutsche Welle [Internet]. Deutsche<br \/>\nWelle (www.dw.com); 2015 Sep 21 [cited 2015<br \/>\nSep 27]; Available from: http:\/\/www.dw.com\/en\/<br \/>\nteenage-refugee-dies-after-consuming-poisonous-<br \/>\nmushroom\/a-18728362<br \/>\nviolent partners wishes and women\u2019s shel-<br \/>\nters may be accessed, however, there are still<br \/>\nmany bureaucratic hurdles. In the case of<br \/>\nviolence, the Institute recommends either<br \/>\nlifting restrictions causing vulnerability for<br \/>\nvictims or introducing fast track procedures<br \/>\nfor victims to offer them different shelters<br \/>\nand making emergency accommodations<br \/>\navailable. It further recommends making<br \/>\nrefugee shelters safer places by ensuring<br \/>\nlockable rooms and sanitary facilities, in-<br \/>\nforming residents about their rights, setting<br \/>\nup women\u2019s rooms, sensitizing staff, inte-<br \/>\ngrating NGOs and ensuring there is female<br \/>\nas well as male security staff at shelters [69].<br \/>\nPregnant women in refugee or migrant<br \/>\ncommunities can have limited access to an-<br \/>\ntenatal care or safe delivery facilities [70].<br \/>\nThis can result in late diagnosis and some-<br \/>\ntimes life-threatening conditions for moth-<br \/>\ners and their babies [8].<br \/>\nIn addition, discrimination and violence<br \/>\nbased on sexual orientation and gender<br \/>\nidentity is an unfortunate reality for refu-<br \/>\ngees who identify as lesbian, gay, bisexual,<br \/>\ntransgender, queer or intersex (LGBTQI).<br \/>\nAlthough data are limited, anecdotal evi-<br \/>\ndence suggests these refugees face addition-<br \/>\nal health threats including psychological<br \/>\nsuch as \u201chumiliation\u201d [71].<br \/>\nImplications for Health<br \/>\nSystems: Examples<br \/>\nEuropean Union<br \/>\nAccording to the Fundamental rights of<br \/>\nmigrants in an irregular situation in the<br \/>\nEuropean Union \u2013 Comparative report<br \/>\nfrom 2011, in \u201c19 out of 27 EU Member<br \/>\nStates migrants in an irregular situation<br \/>\nare entitled to emergency healthcare only\u201d<br \/>\n[72]. For example, Croatia\u2019s law on asylum<br \/>\n(28th<br \/>\nmember state of the European Union)<br \/>\nstates that health care services for asylum<br \/>\nseekers include emergency medical services.<br \/>\nTurkey<br \/>\nIn Turkey, registered refugees are offered<br \/>\nfree primary healthcare services in public<br \/>\nhospitals for both emergency and elec-<br \/>\ntive procedures. Since the beginning of<br \/>\nthe Syrian conflict, 4.383.907 outpatient<br \/>\nvisits have occurred in the temporary shel-<br \/>\nters and 4.914.920 polyclinic examinations<br \/>\nwere performed in hospitals across the<br \/>\ncountry, while 389.837 of them ended up<br \/>\nwith inpatient service. 62.022 deliveries<br \/>\nand 278.035 surgeries were performed ac-<br \/>\ncording to official numbers [10]. This put<br \/>\nthe healthcare system of the country under<br \/>\nextra stress, which had already limitations<br \/>\nwith the shortage of healthcare workers<br \/>\n[73, 74].<br \/>\nLebanon<br \/>\nSince the beginning of the Syrian conflict<br \/>\nin 2011, Lebanon as one of the closest<br \/>\nbordering states has witnessed a contin-<br \/>\nued influx of refugees to reach about 1.5<br \/>\nmillion in official numbers provided by the<br \/>\nUNHCR. This has propelled the country<br \/>\ninto the pole position, having the high-<br \/>\nest refugee per capita in the world (232<br \/>\nrefugees per 1000 inhabitants).The already<br \/>\nstrained healthcare system is now stretched<br \/>\nvery thin with the healthcare needs of the<br \/>\nrefugee population [75]. The drop in vac-<br \/>\ncination rates in Syria has impacted the<br \/>\nreemergence of infectious diseases thought<br \/>\nto be close to eradication from Lebanon<br \/>\nsuch as measles [76, 43].<br \/>\nGreece<br \/>\nGreece faces an unprecedented economic<br \/>\ncrisis that has led the country to a con-<br \/>\ntinuous depression since 2010. The current<br \/>\nrefugee crisis creates therefore tremendous<br \/>\nproblems in Greece, which the Greek state<br \/>\ncannot handle by itself. As a common point<br \/>\nof entry to Europe, lack of first recep-<br \/>\ntion and accommodation infrastructure in<br \/>\nGreece may exacerbate public health issues<br \/>\nand prove hazardous to refugee populations<br \/>\nand local societies.It is a humanitarian need<br \/>\nthat healthcare services and infrastructure<br \/>\nin Greece, a country at Europe\u2019s doorstep,<br \/>\nbe financially supported by European funds<br \/>\nto ensure refugees have access to holistic<br \/>\ncare upon arrival in Europe [77].<br \/>\nGermany<br \/>\nUpon arrival, refugees receive a preliminary<br \/>\nmedical examination and are offered vacci-<br \/>\nnations according to German national rec-<br \/>\nommendations. Due to this policy and the<br \/>\nsheer number of refugees, vaccine stocks for<br \/>\nmany combination vaccines were exhausted<br \/>\nduring the summer of 2015 [78].<br \/>\nRefugees are distributed throughout Ger-<br \/>\nmany under a pre-agreed quota system [79].<br \/>\nLocal authorities are required to provide<br \/>\nfood and shelter for refugees, sometimes<br \/>\nwith a few hours of prior notice [80]. In or-<br \/>\nder to meet the need,gyms,empty school or<br \/>\nstores and tents have been set up as make-<br \/>\nshift shelters with only basic sanitary ser-<br \/>\nvices available [21].<br \/>\nOverall, under German law, refugees are<br \/>\nentitled to free healthcare for alleviating<br \/>\npain and acute disease. The only exception<br \/>\nbeing pregnant women, who are entitled to<br \/>\nthe same health care standard as all pub-<br \/>\nlicly insured women [81]. Until recently<br \/>\nrefugees had to first go to public admin-<br \/>\nistration receive a written approval before<br \/>\nhaving their doctors visit for acute disease<br \/>\ncovered. This has often been criticized as<br \/>\ndiscriminatory, especially as public officials<br \/>\nin charge of granting the visit had no for-<br \/>\nmal medical expertise [82]. Recently most<br \/>\nstates changed statutes to issue refugees<br \/>\nstandard German health insurance cards<br \/>\n[83]. They do not extend coverage, how-<br \/>\never, allow refugees to see doctors without<br \/>\nprior approval and for doctors to receive<br \/>\nreimbursement through standard health<br \/>\ninsurance processes.<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\nBACK TO CONTENTS<br \/>\n96 97<br \/>\n27.\t Chan S. Another Hazard for Migrants in Europe:<br \/>\nPoisonous Mushrooms. The New York Times [Inter-<br \/>\nnet]. 2015 Sep 17 [cited 2015 Sep 27]; Available from:<br \/>\nhttp:\/\/www.nytimes.com\/2015\/09\/18\/world\/europe\/<br \/>\nmigrant-refugee-crisis-poisoning-cases-death-cap-<br \/>\nmushrooms.html<br \/>\n28.\t Ingleby D, Chiarenza A, Deville W. Inequalities in<br \/>\nhealth care for migrants and ethnic minorities [In-<br \/>\nternet]. Maklu; 2012. Available from: https:\/\/books.<br \/>\ngoogle.com\/books?hl=en&#038;lr=&#038;id=HFw8gdmnqXQC<br \/>\n&#038;oi=fnd&#038;pg=PA9&#038;dq=(Inequalities%2Bin%2BHealt<br \/>\nh%2BCare%2Bfor%2BMigrants%2Band%2BEthnic%<br \/>\n2BMinorities%2BVolume%2B2%2BBy%2BDavid%2<br \/>\nBIngleby%2BAntonio%2BChiarenza%2BWalter%2B<br \/>\nDeville&#038;ots=1GjnvOh_7X&#038;sig=TIkps5kU1l4ZzZY<br \/>\nPl_o5oxXOE7c<br \/>\n29.\t Severoni S EU. Refugee Crisis Situation Update<br \/>\n17 September 2015 [Internet]. WHO Regional<br \/>\nOffice Europe; 2015 Sep. Report No.: 1. Avail-<br \/>\nable from: http:\/\/www.euro.who.int\/__data\/assets\/<br \/>\npdf_file\/0004\/288436\/Refugee-Situation-Update-No-<br \/>\n1-rev2.pdf<br \/>\n30.\t Bundesministerium f\u00fcr Gesundheit. Bekanntmachung<br \/>\nnach \u00a7 79 Absatz 5 des Arzneimittelgesetzes (AMG).<br \/>\nBundesanzeiger. 2015 Sep 2;B6.<br \/>\n31.\t WHO Model List of Essential Medicines [Internet].<br \/>\nWorld Health Organization; 2015 Apr. Available from:<br \/>\nhttp:\/\/www.who.int\/selection_medicines\/committees\/<br \/>\nexpert\/20\/EML_2015_FINAL_amended_AUG2015.<br \/>\npdf?ua=1<br \/>\n32.\t Robert Koch Institut. Skabies (Kr\u00e4tze) [Internet].<br \/>\nRKI-Ratgeber f\u00fcr \u00c4rzte. 2009 [cited 2015 Sep 27].<br \/>\nAvailable from: https:\/\/www.rki.de\/DE\/Content\/<br \/>\nInfekt\/EpidBull\/Merkblaetter\/Ratgeber_Skabies.<br \/>\nhtml#doc2374546bodyText10<br \/>\n33.\t Merck Sharp &#038; Dohme Corp. Stromectol Product<br \/>\nInformation [Internet]. 2010 May. 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Lancet [Internet]. 2005; 365(9464): 1099\u2013104.<br \/>\nAvailable from: http:\/\/dx.doi.org\/10.1016\/S0140-<br \/>\n6736(05)71146-6<br \/>\n86.\t Algan Y, Dustmann C, Glitz A, Manning A. The<br \/>\nEconomic Situation of First and Second-Generation<br \/>\nImmigrants in France, Germany and the United King-<br \/>\ndom*. Econ J Nepal [Internet]. Blackwell Publishing<br \/>\nLtd; 2010 Feb 1;120(542):F4\u201330. Available from:<br \/>\nhttp:\/\/dx.doi.org\/10.1111\/j.1468-0297.2009.02338.x<br \/>\n87.\t WMA Statement on Medical Care for Refugees, in-<br \/>\ncluding Asylum Seekers, Refused Asylum Seekers and<br \/>\nUndocumented Migrants, and Internally Displaced<br \/>\nPersons World Medical Association. [Internet]. [cit-<br \/>\ned 2015 Sep 28]. Available from: http:\/\/www.wma.<br \/>\nnet\/en\/30publications\/10policies\/m10\/index.html.<br \/>\npdf?print-media-type&#038;footer-right=[page]\/[toPage]<br \/>\n88.\t Doctors urge government to respond to Syrian refugee<br \/>\ncrisis [Internet]. National Observer. 2015 [cited 2015<br \/>\nSep 28]. Available from: http:\/\/www.nationalobserver.<br \/>\ncom\/2015\/09\/04\/opinion\/doctors-urge-government-<br \/>\nrespond-syrian-refugee-crisis<br \/>\nIsabel Tourneur,<br \/>\nDRK Kliniken Westend, Berlin,<br \/>\nGermany;<br \/>\nMD, MPH, DTMH Xaviour\u00a0Walker,<br \/>\nJohns Hopkins Bloomberg School<br \/>\nof Public Health, USA;<br \/>\nMD, JD, MPH Elizabeth Wiley,<br \/>\nUniversity of Maryland, USA;<br \/>\nMD Caline Mattar,<br \/>\nWashington\u00a0University in St. Louis, USA;<br \/>\nMD Fehim Esen,<br \/>\nTurkish Young Doctors Association,<br \/>\nDevrek State Hospital, Turkey;<br \/>\nMD Goran Mijaljica,<br \/>\nPsychiatric\u00a0Hospital Ugljan and University<br \/>\nof Split School of Medicine, Croatia;<br \/>\nMD, MSc Kostas Roditis,<br \/>\nNational Kapodistrian University<br \/>\nof Athens, Greece;<br \/>\nMD, PhD Kostas Louis,<br \/>\n\u201cKonstantopoulio-Patision\u201d<br \/>\nGeneral Hospital, Greece;<br \/>\nMD, MSc Ahmet Murt,<br \/>\nCerrahpasa\u00a0Medical Faculty,<br \/>\nIstanbul, Turkey;<br \/>\nMD Thorsten Hornung,<br \/>\nUniversity\u00a0of Bonn, Germany<br \/>\nE-mail: Thorsten.hornung@ukb.uni-bonn.de<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\nBACK TO CONTENTS<br \/>\n98 99<br \/>\nJORDAN, 2013-10-28,<br \/>\n\u00a9 ICRC \/ REVOL, Didier<br \/>\nMafraq Governorate. The ICRC and the<br \/>\nJordan Red Crescent Society distribute<br \/>\ndebit cards to vulnerable Syrian families liv-<br \/>\ning in host communities.<br \/>\nThe mechanism for the cash transfer is done<br \/>\nthrough ATM cards issued by a major bank.<br \/>\nThe project will last until March 2014, with<br \/>\none instalment per month. The amount<br \/>\nof cash assistance varies according to the<br \/>\nhousehold size. To help Syrians withstand<br \/>\nwinter, the amount will increase during the<br \/>\ncold season. The ICRC and Palestinian RC<br \/>\nhelped around 1000 syrian families with<br \/>\ntheir cash transfer programme.<br \/>\nAs the conflict continues unabated, Syr-<br \/>\nians are fleeing their homes every day to<br \/>\nseek refuge in Jordan. With winter ap-<br \/>\nproaching, the ICRC and the Jordan Na-<br \/>\ntional Red Crescent Society are finding<br \/>\nnew ways to help them cope with increas-<br \/>\ning needs.<br \/>\nMany Syrians who have found refuge in<br \/>\nJordan depend on aid provided by local and<br \/>\ninternational aid agencies. The vast major-<br \/>\nity of the refugees have been taken in by lo-<br \/>\ncal communities in northern areas near the<br \/>\nSyrian border. Some have not received any<br \/>\nother kind of assistance since arriving in the<br \/>\ncountry.<br \/>\n\u201cBetween 200 and 500 people are arriving<br \/>\ndaily. Most have endured a gruelling jour-<br \/>\nney across the desert,\u201d said Nana Chukhua,<br \/>\nICRC delegate in Jordan. \u201cAs soon as they<br \/>\narrive, they urgently need water, food and<br \/>\nshelter.\u201d<br \/>\n\u201cWe were forced to travel dozens of kilo-<br \/>\nmetres through the desert with scarcely any<br \/>\nfood or water,\u201d said Abu Yazan, a Syrian<br \/>\nrefugee from Homs. \u201cIt was cold, and we<br \/>\nhad to sleep on the ground.\u201d<br \/>\nThe majority have left all their belongings<br \/>\nbehind and cannot meet basic needs such as<br \/>\nfood,health care,house rent,water and elec-<br \/>\ntricity bills. Besides distributing relief items<br \/>\nto the refugees, the ICRC and the Jordan<br \/>\nNational Red Crescent Society launched a<br \/>\nprogramme in October to provide cash as-<br \/>\nsistance for 1,000 families in Mafraq gover-<br \/>\nnorate, northern Jordan, with the dual aim<br \/>\nof helping them and easing the burden on<br \/>\nlocal communities.<br \/>\n\u201cThe cash money will definitely help us<br \/>\ncover our basic needs, mainly house rent,\u201d<br \/>\nsaid Um Anwar, a 32-year-old Syrian who<br \/>\nresides in Mafraq.\u201cThe money will also help<br \/>\nme obtain treatment for my 13-year-old<br \/>\ndaughter,\u201d the mother of five added.<br \/>\nAn innovative cash transfer programme:<br \/>\nIn Jordan, the vast majority of Syrian refu-<br \/>\ngees live in host communities and often<br \/>\nhave problems meeting their basic needs.<br \/>\nTo help them with expenses not covered<br \/>\nby other relief mechanisms, the ICRC and<br \/>\nthe Jordan National Red Crescent Soci-<br \/>\nety launched a cash assistance programme<br \/>\nin October in Mafraq governorate, in the<br \/>\nnorth of the country, which will be imple-<br \/>\nmented over a period of six months.<br \/>\nAn initial group of 1,000 families have<br \/>\nstarted receiving debit cards issued by a ma-<br \/>\njor bank that will allow them to withdraw<br \/>\nmoney directly from ATM machines. The<br \/>\namount of money (from USD 70 to 310)<br \/>\nmade available to each family depends on<br \/>\nthe size of the household and will be in-<br \/>\ncreased during winter months.<br \/>\nAs the ICRC\u2019s Hekmat Sharabi puts it, this<br \/>\nprogramme \u201cis much more flexible than<br \/>\njust giving them assistance that they might<br \/>\nnot consider suitable. It preserves people\u2019s<br \/>\ndignity by giving them the opportunity to<br \/>\ndetermine on their own what they are most<br \/>\nin need of.\u201d<br \/>\nIRAQ, 2013-09-25<br \/>\n\u00a9 ICRC \/ MOHAMMAD, Flamerz<br \/>\nDohuk governorate, Qsrouk sub-district,<br \/>\nQsrouk transit camp. Distribution of ICRC<br \/>\nnon-food assistance to Syrian refugees. A<br \/>\nyoung girl carries the thermos her family<br \/>\nreceived during the distribution.<br \/>\nIn Qasrouk kits were distributed to a total<br \/>\nof 561 persons (99 families and 35 singles).<br \/>\nThe kits consisted of basic hygiene and<br \/>\nhousehold items (stove, bucket, kettle, tea<br \/>\npot, thermoses and tarpaulin).<br \/>\nIRAQ, 2015-01-16<br \/>\n\u00a9 ICRC \/ ACHKAR, Nora<br \/>\nIraqi Kurdistan, Penjwin. ICRC assistance<br \/>\noperation.<br \/>\nOn Friday 16 January, the ICRC provides<br \/>\nemergency aid to nearly 180 displaced per-<br \/>\nsons who are currently living in Penjwin, 46<br \/>\nkm from Sulaymaniyah. Penjwin lies at an<br \/>\naltitude of 1500 m, where meteorological<br \/>\nconditions are harsh in winter.<br \/>\nA similar distribution operation took place<br \/>\nin December 2014,when the ICRC provid-<br \/>\ned supplies for 660 people. The people that<br \/>\nthe ICRC is helping have fled from Nayna-<br \/>\nwa, Salah al-Din, and Diyala governorates<br \/>\nin Iraq, and from Ayn al-Arab\/Kobani.<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\nInternational Committee of the Red Cross activities for<br \/>\nrefugees\/displaced persons in the Middle East<br \/>\nBACK TO CONTENTS<br \/>\n100 101<br \/>\nJORDAN, 2013-10-29<br \/>\n\u00a9 ICRC \/ REVOL, Didier<br \/>\nRuwaishid area, assembly point in Bustana.<br \/>\nThe ICRC distributes blankets, jerrycans<br \/>\nand hygiene items.<br \/>\nThe ICRC has, since July 2013, equipped<br \/>\nthree asssembly points and two transit sites<br \/>\nin the area with water tanks and drinking-<br \/>\nwater coolers, sanitation facilities and waste<br \/>\ncontainers; it has also ensured temporary<br \/>\naccommodation for refugees fleeing Syria<br \/>\nAs the conflict continues unabated, Syrians<br \/>\nare fleeing their homes every day to seek<br \/>\nrefuge in Jordan. With winter approach-<br \/>\ning, the ICRC and the Jordan National Red<br \/>\nCrescent Society are finding new ways to<br \/>\nhelp them cope with increasing needs.<br \/>\nMany Syrians who have found refuge in<br \/>\nJordan depend on aid provided by local and<br \/>\ninternational aid agencies. The vast major-<br \/>\nity of the refugees have been taken in by lo-<br \/>\ncal communities in northern areas near the<br \/>\nSyrian border. Some have not received any<br \/>\nother kind of assistance since arriving in the<br \/>\ncountry.<br \/>\n\u00abBetween 200 and 500 people are arriving<br \/>\ndaily. Most have endured a gruelling jour-<br \/>\nney across the desert,\u00bb said Nana Chukhua,<br \/>\nICRC delegate in Jordan. \u00abAs soon as they<br \/>\narrive, they urgently need water, food and<br \/>\nshelter.\u00bb<br \/>\n\u00abWe were forced to travel dozens of kilo-<br \/>\nmetres through the desert with scarcely any<br \/>\nfood or water,\u00bb said Abu Yazan, a Syrian<br \/>\nrefugee from Homs. \u00abIt was cold, and we<br \/>\nhad to sleep on the ground.\u00bb<br \/>\nThe majority have left all their belongings<br \/>\nbehind and cannot meet basic needs such as<br \/>\nfood,health care,house rent,water and elec-<br \/>\ntricity bills. Besides distributing relief items<br \/>\nto the refugees, the ICRC and the Jordan<br \/>\nNational Red Crescent Society launched a<br \/>\nprogramme in October to provide cash as-<br \/>\nsistance for 1,000 families in Mafraq gover-<br \/>\nnorate, northern Jordan, with the dual aim<br \/>\nof helping them and easing the burden on<br \/>\nlocal communities.<br \/>\nJORDAN, 2013-10-30<br \/>\n\u00a9 ICRC \/ REVOL, Didier<br \/>\nGrowing numbers of families in search of<br \/>\na safe haven are embarking on a danger-<br \/>\nous journey across Syria to border areas<br \/>\nin eastern Jordan. Between 200 and 500<br \/>\npeople arrive every day in this remote des-<br \/>\nert area.<br \/>\nRefugees, iamong them the elderly and the<br \/>\nvery young, walk long distances, mostly at<br \/>\nnight, to cross the border.<br \/>\nBecause of the intensity of the fighting on<br \/>\nthe Syrian side, the usual entry points in<br \/>\neastern Jordan are now harder to reach for<br \/>\nthe refugees. The refugees are gathered by<br \/>\nthe Jordan Armed Forces, first at assembly<br \/>\npoints and then at transit sites.<br \/>\nAs the conflict continues unabated, Syrians<br \/>\nare fleeing their homes every day to seek<br \/>\nrefuge in Jordan. With winter approach-<br \/>\ning, the ICRC and the Jordan National Red<br \/>\nCrescent Society are finding new ways to<br \/>\nhelp them cope with increasing needs.<br \/>\nMany Syrians who have found refuge in<br \/>\nJordan depend on aid provided by local and<br \/>\ninternational aid agencies. The vast major-<br \/>\nity of the refugees have been taken in by lo-<br \/>\ncal communities in northern areas near the<br \/>\nSyrian border. Some have not received any<br \/>\nother kind of assistance since arriving in the<br \/>\ncountry.<br \/>\n\u00abBetween 200 and 500 people are arriving<br \/>\ndaily. Most have endured a gruelling jour-<br \/>\nney across the desert,\u00bb said Nana Chukhua,<br \/>\nICRC delegate in Jordan. \u00abAs soon as they<br \/>\narrive, they urgently need water, food and<br \/>\nshelter.\u00bb<br \/>\n\u00abWe were forced to travel dozens of kilo-<br \/>\nmetres through the desert with scarcely any<br \/>\nfood or water,\u00bb said Abu Yazan, a Syrian<br \/>\nrefugee from Homs. \u00abIt was cold, and we<br \/>\nhad to sleep on the ground.\u00bb<br \/>\nThe majority have left all their belongings<br \/>\nbehind and cannot meet basic needs such as<br \/>\nfood,health care,house rent,water and elec-<br \/>\ntricity bills. Besides distributing relief items<br \/>\nto the refugees, the ICRC and the Jordan<br \/>\nNational Red Crescent Society launched a<br \/>\nprogramme in October to provide cash as-<br \/>\nsistance for 1,000 families in Mafraq gover-<br \/>\nnorate, northern Jordan, with the dual aim<br \/>\nof helping them and easing the burden on<br \/>\nlocal communities.<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\nBACK TO CONTENTS<br \/>\n102 103<br \/>\nJORDAN, 2013-10-30<br \/>\n\u00a9 ICRC \/ REVOL, Didier<br \/>\nRuwaished area, assembly point in Bustana.<br \/>\nICRC trucks regularly deliver blankets, jer-<br \/>\nrycans and hygiene items to refugees fleeing<br \/>\nSyria; twice a day, a local NGO distributes<br \/>\nmeals paid for by the ICRC.<br \/>\nThe ICRC has, since July 2013, equipped<br \/>\nthree asssembly points and two transit sites<br \/>\nin the area with water tanks and drinking-<br \/>\nwater coolers, sanitation facilities and waste<br \/>\ncontainers; it has also ensured temporary<br \/>\naccommodation for refugees fleeing Syria.<br \/>\nAs the conflict continues unabated, Syrians<br \/>\nare fleeing their homes every day to seek<br \/>\nrefuge in Jordan. With winter approach-<br \/>\ning, the ICRC and the Jordan National Red<br \/>\nCrescent Society are finding new ways to<br \/>\nhelp them cope with increasing needs.<br \/>\nMany Syrians who have found refuge in<br \/>\nJordan depend on aid provided by local and<br \/>\ninternational aid agencies. The vast major-<br \/>\nity of the refugees have been taken in by lo-<br \/>\ncal communities in northern areas near the<br \/>\nSyrian border. Some have not received any<br \/>\nother kind of assistance since arriving in the<br \/>\ncountry.<br \/>\n\u00abBetween 200 and 500 people are arriving<br \/>\ndaily. Most have endured a gruelling jour-<br \/>\nney across the desert,\u00bb said Nana Chukhua,<br \/>\nICRC delegate in Jordan. \u00abAs soon as they<br \/>\narrive, they urgently need water, food and<br \/>\nshelter.\u00bb<br \/>\n\u00abWe were forced to travel dozens of kilo-<br \/>\nmetres through the desert with scarcely any<br \/>\nfood or water,\u00bb said Abu Yazan, a Syrian<br \/>\nrefugee from Homs. \u00abIt was cold, and we<br \/>\nhad to sleep on the ground.\u00bb<br \/>\nThe majority have left all their belongings<br \/>\nbehind and cannot meet basic needs such as<br \/>\nfood,health care,house rent,water and elec-<br \/>\ntricity bills. Besides distributing relief items<br \/>\nto the refugees, the ICRC and the Jordan<br \/>\nNational Red Crescent Society launched a<br \/>\nprogramme in October to provide cash as-<br \/>\nsistance for 1,000 families in Mafraq gover-<br \/>\nnorate, northern Jordan, with the dual aim<br \/>\nof helping them and easing the burden on<br \/>\nlocal communities.<br \/>\nLEBANON, 2013-08-05<br \/>\n\u00a9 ICRC \/ SPAULL, John<br \/>\nBekaa Valley, close to the Syrian border,<br \/>\nnear Bar Elias.Tal Sarhoun informal Syrian<br \/>\nrefugee settlement. Children huddle around<br \/>\na flimsy tent.<br \/>\nSeveral makeshift settlements of this sort<br \/>\nhost hundreds of families, especially in the<br \/>\nBekaa region.<br \/>\nThe ICRC is working to help family mem-<br \/>\nbers separated by the conflict from their<br \/>\nloved ones to reestablish links. It has also<br \/>\nreminded the Lebanese government of its<br \/>\nresponsibility to ensure respect for the prin-<br \/>\nciple of non-refoulement.<br \/>\nLEBANON, 2013-08-05<br \/>\n\u00a9 ICRC \/ SPAULL, John<br \/>\nBekaa Valley, close to the Syrian border,<br \/>\nnear Bar Elias.Tal Sarhoun informal Syrian<br \/>\nrefugee settlement.<br \/>\nThis informal refugee settlement hosts<br \/>\naround 500 families. Having fled their<br \/>\nhomes, taking little of their belongings with<br \/>\nthem, the refugees need essential assistance,<br \/>\nranging from shelter, to food, water, hygiene<br \/>\nitems and sleeping material.<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\nBACK TO CONTENTS<br \/>\n104 105<br \/>\nLEBANON, 2012-10-09, \u00a9 ICRC \/ PARRISH, Paula<br \/>\nTripoli. ICRC nurses visits a Syrian wounded.<br \/>\nSYRIA, 2012-06-22, \u00a9 ICRC \/ GARCIA VILANOVA, Ricardo<br \/>\nHoms governorate, Qussayr. A doctor takes care of a child in a<br \/>\nfield hospital.<br \/>\nSYRIA, 2012-08-24, \u00a9 ICRC \/ GARCIA VILANOVA, Ricardo<br \/>\nAleppo. A wounded man is tended to.<br \/>\nSYRIA, 2013-03-18<br \/>\n\u00a9 ICRC \/ s.n.<br \/>\nBetween Aleppo and Manbij. An ICRC<br \/>\nconvoy on its way to deliver medical sup-<br \/>\nplies to Manbij an opposition held area.<br \/>\nSyria: Heavy fighting in Aleppo plagues<br \/>\nlives of hundreds of thousands<br \/>\nDamascus\/Geneva (ICRC) &#8211; Humanitari-<br \/>\nan needs in Aleppo are enormous,according<br \/>\nto personnel from the International Com-<br \/>\nmittee of the Red Cross (ICRC) who have<br \/>\njust concluded a five-day visit to Aleppo<br \/>\ngovernorate together with the Syrian Arab<br \/>\nRed Crescent.<br \/>\nDuring the visit, they gauged the humani-<br \/>\ntarian situation and delivered much-needed<br \/>\nmedical assistance.<br \/>\n\u00abThere are tens of thousands of displaced<br \/>\npeople in the governorate with no income<br \/>\nand no savings who depend on assistance<br \/>\nto survive,\u00bb said Marianne Gasser, head of<br \/>\nthe ICRC delegation in Syria, upon her re-<br \/>\nturn from the governorate. \u00abApart from the<br \/>\npressing humanitarian needs, several roads,<br \/>\nhospitals, schools, other public facilities and<br \/>\nworld heritage sites have been damaged.<br \/>\nEssential public services such as the distri-<br \/>\nbution of power and water have also been<br \/>\ndisrupted as a result of the heavy fighting<br \/>\nthat has plagued the governorate over the<br \/>\npast nine months.\u00bb<br \/>\nThe ICRC has been unable to return to<br \/>\nAleppo since July of last year because of<br \/>\nthe ongoing fierce fighting. However, the<br \/>\nSyrian Arab Red Crescent never stopped<br \/>\ndelivering food and household essentials,<br \/>\nwith ICRC support. In addition, the ICRC<br \/>\nensured that potable water was available<br \/>\nto the population. \u00abOur trip to Aleppo is<br \/>\nan important step forward. It is a good ex-<br \/>\nample of how continuous dialogue with all<br \/>\nparties concerned yields results, and makes<br \/>\nit possible to reach people in need, includ-<br \/>\ning in opposition-controlled areas,\u00bb added<br \/>\nMs Gasser.<br \/>\nTogether with the Syrian Arab Red Cres-<br \/>\ncent, the ICRC visited a number of differ-<br \/>\nent areas in the governorate, including op-<br \/>\nposition-held territory in the eastern parts<br \/>\nof Aleppo city such as Bustan Al-Qasr and<br \/>\nMasaken Hanano, and Manbij in Rural<br \/>\nAleppo. \u00abDuring these visits, we assessed<br \/>\nhumanitarian needs and spoke to people<br \/>\nsuffering the effects of the violence to better<br \/>\nunderstand their needs as well as the situa-<br \/>\ntion,\u00bb said Ms Gasser.<br \/>\nWorking with the Syrian Arab Red Cres-<br \/>\ncent and the local water boards, ICRC wa-<br \/>\nter engineers surveyed the effect the fight-<br \/>\ning has had on the supply of clean drinking<br \/>\nwater in the city of Aleppo and surrounding<br \/>\nrural areas. \u00abWe are planning to go forward<br \/>\nwith a number of upgrades and to provide<br \/>\nsupport that will help the Aleppo water<br \/>\nboard solve some of the problems it is fac-<br \/>\ning,\u00bb said Antonio Bolinches, an ICRC<br \/>\nwater engineer who participated in the visit.<br \/>\nICRC health personnel also visited the<br \/>\ngovernorate and checked on a number of<br \/>\nhealth-care facilities, where they provided<br \/>\nmuch-needed medical supplies and drugs<br \/>\nfor chronic diseases.<br \/>\nThe Syrian Arab Red Crescent branch in<br \/>\nAleppo was highly involved in the activities<br \/>\ncarried out during the visit. \u00abThese young<br \/>\nvolunteers are doing tremendous work on<br \/>\nthe ground,\u00bb said Ms Gasser. \u00abI was moved<br \/>\nby their dedication and commitment to<br \/>\nhelping everyone in need \u2013 irrespective of<br \/>\nwhere they are.\u00bb<br \/>\nSYRIA, 2012-07-08, \u00a9 ICRC \/ GARCIA VILANOVA, Ricardo<br \/>\nHoms governorate, Qussayr. A wounded man is tended to at a<br \/>\nhospital.<br \/>\nSYRIA, 2013-04, \u00a9 ICRC \/ CARRIN, Jeroen<br \/>\nZabdani. Ambulance damaged.<br \/>\nSYRIA, 2014-02, \u00a9 ICRC \/ KAS BARSOUM, Jack<br \/>\nAleppo, Internally Displaced People Centre.The black buildings,<br \/>\nwhich are used by the internally displaced persons.<br \/>\nRefugees and Health CareRefugees and Health Care<br \/>\nBACK TO CONTENTS<br \/>\n106 107<br \/>\nFRANCEFRANCE Person Centered MedicinePerson Centered Medicine<br \/>\nIt has been extensively shown that mental<br \/>\nhealth problems or symptoms are frequently<br \/>\nbrought up in the context of primary care<br \/>\neither as the main reason to consult or as a<br \/>\nconcomitant symptom. It is at the heart of<br \/>\nthe WHO WONCA report \u201cIntegrating<br \/>\nmental health into primary care\u201d[1] and also<br \/>\nextensively demonstrated by several well-<br \/>\ndesigned studies more or less in line with the<br \/>\nAlma Ata declaration on primary health care<br \/>\n(see for example) [2,3].Hence,it can no lon-<br \/>\nger be disputed that primary care is the best<br \/>\nsetting to ensure that people get the mental<br \/>\nhealth care they need, not only because \u201cit<br \/>\nis accessible, affordable, acceptable and cost<br \/>\neffective\u201d but also because while promoting<br \/>\n\u201cearly diagnosis, respect of human rights and<br \/>\nsocial integration\u201d,\u201cprimary care also helps to<br \/>\nensure that all people are treated in a holistic<br \/>\nmanner, addressing both their physical and<br \/>\nmental health needs\u201d[1].To the point that \u2013<br \/>\neven if there is still a lack of evidence*\u00a0\u2013 this<br \/>\n*\u2002 Mainly because there is a lack of criteria and met-<br \/>\nrics to evaluate these aspects<br \/>\nholistic ambition is fulfilled in this perspec-<br \/>\ntive, many countries have tried more or less<br \/>\nsuccessfully to restructure their organization<br \/>\nbased on these principles including practical,<br \/>\nrather than conceptual, adaptations to their<br \/>\ncultural and socio economic context.In many<br \/>\ncases their main objective is to find the most<br \/>\ncost effective and sustainable way to diagnose<br \/>\na nosographic mental disorder using brief<br \/>\nevidence based screening for such conditions<br \/>\n[4].In this type of adaptation \u201cholism\u201dis lim-<br \/>\nited to the integration of a somatic and men-<br \/>\ntal disorder centered appraisal of the health<br \/>\nstatus without real consideration of the per-<br \/>\nson as a whole including his values, expec-<br \/>\ntations and subjective aspects. An apparent<br \/>\nunanimity on benchmarked principles hides<br \/>\na profound heterogeneity of their definitions<br \/>\nand, not surprisingly, a strong implicit ten-<br \/>\ndency to maintain the health organizations<br \/>\nin their usual biomedical type of approach to<br \/>\nphysical and mental health: a disorder cen-<br \/>\ntered approach. Various indicators, and par-<br \/>\nticularly criticisms and complaints coming<br \/>\nfrom users and stakeholders, show that this<br \/>\nperspective is far from satisfactory.<br \/>\nTowards a Person<br \/>\nCentered Perspective<br \/>\nOne of the main problems health profes-<br \/>\nsionals have to face when dealing with<br \/>\nmental health or psychological issues is the<br \/>\nfact that \u2013 maybe more than other medi-<br \/>\ncal disciplines \u2013 Psychiatry and Mental<br \/>\nHealth are exposed to the negative effects<br \/>\nof a disorder centered approach. Because of<br \/>\nthe many competing theories about the very<br \/>\nnature of one\u2019s mental life a disorder cen-<br \/>\ntered approach risks neglecting many of the<br \/>\nnon-objective aspects of the person\u2019s mental<br \/>\nhealth,including key aspects such as subjec-<br \/>\ntivity and psychodynamic dimensions. The<br \/>\nimplicit or explicit tendency is to mimic the<br \/>\nparadigm based on the biomedical classifi-<br \/>\ncations in other medical disciplines.<br \/>\nThe first stake of a person-centered per-<br \/>\nspective is to fight against this abusive re-<br \/>\nductionism that leaves us \u201cwith half a sci-<br \/>\nence\u201d\u00a0[5] and landmarks not well adapted<br \/>\nto clinical practice [6]. The objective of this<br \/>\npaper is to briefly consider and discuss the<br \/>\nprocess allowing a professional to access<br \/>\nsubjective and psychodynamic dimensions<br \/>\nof the patient\u2019s health status and consider<br \/>\nhow this process could be integrated into<br \/>\nprimary care.<br \/>\nIn this perspective, the modernity and<br \/>\noriginality of Person Centered Medicine<br \/>\n(PCM) resides in the fact that it does not<br \/>\nsatisfy itself with asserting its principles<br \/>\nbut strives to define conditions for effective<br \/>\nimplementation of this ambition in each<br \/>\nmedical situation. What counts the most<br \/>\nhere is to meet real patients\u2019 needs and not<br \/>\nthose of more or less paradigmatic entities<br \/>\ndefined by each medical speciality which<br \/>\ntrigger the reductionist approach imposed<br \/>\nby the research methodology in a \u201cclassical\u201d<br \/>\nEvidence-Based Medicine approach.<br \/>\nThree conditions must be met to reach this<br \/>\ngoal [7,8]:<br \/>\n\u2022\t To take into account the whole being of the<br \/>\npatient (I am myself and my context) [9].<br \/>\n\u2022\t To consider the diagnosis and therapeu-<br \/>\ntic choices as a joint process involving the<br \/>\nperson of the patient, the persons of the<br \/>\ncarers (family and caregivers in general),<br \/>\nand the person of the clinician.<br \/>\n\u2022\t To consider as essential the subjective as-<br \/>\npects of the person\u2019s health situation, and<br \/>\nnot only the objective aspects of the ill-<br \/>\nness.<br \/>\nThis last condition is the focus of this brief<br \/>\npaper, starting with the idea that, in addi-<br \/>\ntion to the attention paid to the medico-<br \/>\nbiological aspects of the person\u2019s health<br \/>\nstatus, a person centred assessment needs to<br \/>\ngive enough consideration to the patient\u2019s<br \/>\nsubjective feelings. Whether or not we sus-<br \/>\npect a psychic or psychosomatic causality to<br \/>\nthe disorder that a patient brings to us, it is<br \/>\nessential to keep in perspective the factors<br \/>\ninvolved in the patient\u2019s health situation.<br \/>\n\u201cBeyond reasserting this principle, we need<br \/>\nto utterly enhance the methodology for ac-<br \/>\ncessing these subjective dimensions among<br \/>\ndifferent partners involved in the diagnos-<br \/>\ntic process and the therapeutic relation-<br \/>\nship\u201d[10]. For the professionals, the only<br \/>\nway to access these subjective dimensions is<br \/>\nthrough what the patient (and or his carers)<br \/>\nsays in words or shows in acting, as long as<br \/>\nthese words or acts can trigger in the pro-<br \/>\nfessionals enough empathy to approach the<br \/>\npatient\u2019s subjective feelings to which these<br \/>\nexpressions are related.<br \/>\nAt first considered as the professional\u2019s<br \/>\nability to listen sympathetically to the<br \/>\ncomments of the patient and to integrate<br \/>\nhis wishes and needs, the notion of em-<br \/>\npathy has gradually widened to include<br \/>\nrepresentations that the physician (or the<br \/>\nhealth professional) makes of the clinical<br \/>\nsituation in which the person in need of<br \/>\ncare is involved. In short, these are repre-<br \/>\nsentations that the professional makes of<br \/>\nthe health situation of the person suffer-<br \/>\ning through his\/her (the professional) own<br \/>\nempathy, triggered by the words and the<br \/>\nacts of the patients and their caregivers.<br \/>\nThis mechanism is well described by the<br \/>\nconcept of \u201cmetaphorizing-empathy\u201d pro-<br \/>\nposed by Lebovici [12] from his work with<br \/>\nbabies and their mothers. It is also close<br \/>\nto the notion of \u201cnarrative empathy\u201d pro-<br \/>\nposed by Jacques Hochmann [13] based<br \/>\non his work with autistic children and on<br \/>\nthe philosophical ideas brought by Paul<br \/>\nRicoeur, a famous French phenomenolo-<br \/>\ngist, in his book \u201cTime and Narrative\u201d[14].<br \/>\nIt is also consistent with Kleinman\u2019s as-<br \/>\nsumptions [15] on illness narratives. This<br \/>\nimportant development in PCM marked<br \/>\nthe full recognition of the role of the phy-<br \/>\nsician\u2019s subjectivity as a diagnostic and<br \/>\ntreatment tool in the physician-patient<br \/>\nrelationship.<br \/>\nTo approach the subjectivity of the person (in<br \/>\nboth its conscious and unconscious aspects)<br \/>\n[10] the physician has to use his personal<br \/>\ncommitment in the relation with the patient<br \/>\nand his use of his metaphorizing empathy.<br \/>\nThis perspective is very consistent with the<br \/>\nreality of medical practice that, in one form<br \/>\nor another, must deal with this vital dimen-<br \/>\nsion in every patient.Moreover,by establish-<br \/>\ning the subjectivity of the physician as a tool<br \/>\nfor understanding the patient and his disor-<br \/>\nder, the subjective involvement of the pro-<br \/>\nfessional regains positive status which was<br \/>\nlost with the progress of objective technical<br \/>\nmedicine. In this perspective the subjectivity<br \/>\nof the professional can be properly included<br \/>\nin practice and training if enough space is<br \/>\ngiven to work it through. Rather than train-<br \/>\ning the professionals to fight against their<br \/>\nsubjective movements or to deny it and to<br \/>\nprevent them from getting closer to the<br \/>\npatient\u2019s personal needs, Person Centered<br \/>\nMedicine (PCM) proposes to train them to<br \/>\nuse these subjective movements as their best<br \/>\ntool to access the patient\u2019s subjectivity.Thus,<br \/>\nPCM acknowledges relevance for clinical<br \/>\npractice of the clinician\u2019s congruence in the<br \/>\nrelationship, (i.e. his or her access to experi-<br \/>\nences arising in resonance with the patient).<br \/>\nA required condition is, for professionals, to<br \/>\nbe trained to work it through properly, and<br \/>\ndevelop enough reflexive capacities. This<br \/>\nwould enable them to take subjectivity and<br \/>\nintersubjectivity as one of the bricks of the<br \/>\ntherapeutic relationship, i.e. the interactive<br \/>\nconstruction they should build with the pa-<br \/>\ntient and for him or her, involving all those<br \/>\nwho are contributing to their health care and<br \/>\nhealth status [10]. The teamwork and peer<br \/>\nsupervision are crucial to enhance and sus-<br \/>\ntain this interactive process.<br \/>\nWhat about subjectivity and<br \/>\nnarrative in primary care?<br \/>\nObviously, subjectivity is of crucial impor-<br \/>\ntance in primary care, not only because a<br \/>\nprimary care visit usually is the first contact<br \/>\nwith health professionals but also because it<br \/>\nis the first step in a process transforming a<br \/>\nsuffering or a distress into a medical disease<br \/>\nor disorder. In this complex process con-<br \/>\ntributing eventually to the transformation<br \/>\nof \u201cpain into suffering\u201d [16]*, the proximity<br \/>\nof primary care with the person\u2019s every day<br \/>\nlife can obviously be a major asset to take<br \/>\ninto account the subjective feelings induced<br \/>\nby his\/her health experience and status, and<br \/>\npotentially their subjective determinants. It<br \/>\nis generally considered and well document-<br \/>\ned that this asset contributes to the acces-<br \/>\nsibility of care and their cost effectiveness<br \/>\nin most medical conditions. However, there<br \/>\nare emerging concerns that this asset could<br \/>\nbecome an obstacle to care when proximal<br \/>\nrelations do not help the patient to address<br \/>\nthe subjective aspects of his health in rela-<br \/>\ntion or not with his\/her somatic condition.<br \/>\nSchematically, three reasons can transform<br \/>\nprimary cares proximity and generality into<br \/>\nan obstacle for such subjective appraisal:<br \/>\n\u2022\t The patient\u2019s fear to disclose a stigmatiz-<br \/>\ning situation to a health professional in-<br \/>\ntegrated in his every day life<br \/>\n\u2022\t His difficulty to recognize subjective as-<br \/>\npects and psychological distress related<br \/>\nto health questions (physical, mental or<br \/>\nboth) due to the health problem itself,<br \/>\neither when this difficulty is one of the<br \/>\nsymptoms of this condition (Alexithymia<br \/>\nas symptom of various health disorders**)<br \/>\nor when the pervasiveness of the somatic<br \/>\nissues tends to mask the psychosocial as-<br \/>\npects of the disease<br \/>\n\u2022\t In these various situations,the lack of time<br \/>\nand expertise of primary care\u2019s profession-<br \/>\nals to recognize and overcome adequately<br \/>\nsuch obstacles in clinical situations<br \/>\n*\u2002 For Paul Ricoeur, there is a crucial difference<br \/>\nbetween Pain and Suffering. In Pain, physical or<br \/>\npsychical, painful experience suppresses all psychical<br \/>\nrepresentations and reduces communication with<br \/>\nothers, whereas in Suffering, the painful experience<br \/>\ntriggers psychical representations and the need to<br \/>\ncommunicate with others [17].<br \/>\n**\u2002 It can be related to various health issues or dis-<br \/>\norders: suffering Adolescents [18], Psychosomatic<br \/>\nconditions [19] , Personality disorders [20], or other<br \/>\nmedical of psychiatric illnesses [21].<br \/>\nSubjectivity and Narratives in Primary Care:<br \/>\nA Person Centered Issue<br \/>\nMichel Botbol<br \/>\nBACK TO CONTENTS<br \/>\n108 109<br \/>\nPerson Centered MedicineUNITED STATES OF AMERICAFRANCEPerson Centered Medicine<br \/>\nIn a person-centered perspective, these<br \/>\nobstacles should be addressed in the<br \/>\nsituations in which they occur. While<br \/>\nin many cases, this could be achieved<br \/>\nthrough the better promotion of person-<br \/>\ncentered medicine principles (given that<br \/>\nperson-centeredness in medicine is not<br \/>\nonly an ethical stance but also a techni-<br \/>\ncal advancement), we have to study more<br \/>\nclosely if the current \u201cWHO service or-<br \/>\nganization pyramid for an optimal mix of<br \/>\nservices for mental health\u201d [1:16] is suf-<br \/>\nficiently adapted to tackle the problem<br \/>\nraised by the integration of the subjective<br \/>\naspects of health into health care. To do<br \/>\nso, there is an urgent need to elaborate rel-<br \/>\nevant metrics to evaluate more thoroughly<br \/>\nhow this issue is tackled in the currently<br \/>\nrecommended health service models. My<br \/>\nhypothesis is that, if we want to address<br \/>\nseriously the problem raised by the inte-<br \/>\ngration of subjective dimensions into pri-<br \/>\nmary health care, we may have to consider<br \/>\namending this optimal model to make<br \/>\nsure that renouncing the integration of<br \/>\nsubjective aspects of health into primary<br \/>\ncare will not be the price to pay to the cost<br \/>\neffectiveness, affordability and transpar-<br \/>\nency claimed by the model.<br \/>\nConclusion<br \/>\nPCM has brought back the person of the<br \/>\npatient at the centre of medicine, allowing<br \/>\nintegrating the subjective dimensions of<br \/>\nthe patient\u2019s mental health into the health<br \/>\ncares from where they have been generally<br \/>\nexcluded by the disease-centered approach.<br \/>\nBecause it involves the personal commit-<br \/>\nment of the health professional and his<br \/>\nempathic capacities the approach of this<br \/>\ndimension needs time and specific training.<br \/>\nAs first interface between the patients and<br \/>\nthe health system, primary care is of cru-<br \/>\ncial importance for the implementation of<br \/>\nperson-centered principles into the health<br \/>\nsystem. It is the reason why, after being the<br \/>\nfocus of the International College for Per-<br \/>\nson Centered Medicine (ICPCM) last Ge-<br \/>\nneva Conference, it is going to be the topic<br \/>\nof the 2015 ICPCM International Con-<br \/>\ngress in London.The usefulness of the opti-<br \/>\nmal use of primary care is well documented<br \/>\nfor its cost effectiveness and affordability; in<br \/>\ncontrast, however, more studies are needed<br \/>\nto better know the conditions that primary<br \/>\ncares have to meet to be person-centered,<br \/>\nespecially when it comes to integrating sub-<br \/>\njective aspects of health. This paper claims<br \/>\nthat, besides the well-demonstrated useful-<br \/>\nness of the primary care oriented model,<br \/>\nthere is still a long way to go to ensure that<br \/>\nthis subjective dimension will not be lost in<br \/>\nprimary care.<br \/>\nReferences<br \/>\n1.\t WHO and Wonca (2008) Integrating mental<br \/>\nhealth into primary care: a global perspective.<br \/>\nWHO Library.<br \/>\n2.\t Berkel H, Henderson J, Henke N, et al. Mental<br \/>\nhealth promotion and prevention strategies for<br \/>\ncoping with anxiety, depression, and stress relat-<br \/>\ned disorders in Europe (2001- 2003). Research<br \/>\nreport 1001. Bremerhaven: Federal Institute for<br \/>\nOccupational Safety and Health 2004<br \/>\n3.\t Hickie I. Can we reduce the burden of depres-<br \/>\nsion? The Australian experience with beyond<br \/>\nblue: the national depression initiative. Austral-<br \/>\nian Psychiatry 2004: 12, 38-46<br \/>\n4.\t Spitzer RL, Williams JB, Kroenke K, Linzer M,<br \/>\nde Gruy FV 3rd, Hahn SR, Brody D, Johnson<br \/>\nJG. Utility of a new procedure for diagnosing<br \/>\nmental disorders in primary care: The PRIME-<br \/>\nMD 1000 study. JAMA 1994; 272: 1749-1756<br \/>\n5.\t Strauss JS. Diagnosis and reality: A noun is a<br \/>\nterrible thing to waste. Psychopathology, Spe-<br \/>\ncial Issue on Philosophical and Methodological<br \/>\nFoundations of Psychiatric Diagnosis 2005; 38:<br \/>\n189-191<br \/>\n6.\t Mises R, Quemada N, Botbol M, Burstejn C,<br \/>\nGarrabe J, Golse B, Jeammet P, Plantade A,<br \/>\nPortelli C, Thevenot JP. French classification for<br \/>\nChild and Adolescent mental disorders. Psycho-<br \/>\npathology 2002; 2: 3<br \/>\n7.\t Mezzich JE, Salloum I, Cloninger R et al. Per-<br \/>\nson-centered integrative diagnosis: conceptual<br \/>\nbases and structural model. Canadian Journal of<br \/>\nPsychiatry 2010; 55: 701-708<br \/>\n8.\t Botbol M. Du manifeste au subjectif: ce qu\u2019est<br \/>\nla m\u00e9decine de la personne [From objectivity to<br \/>\nsubjectivity: What is Person Centered Medi-<br \/>\ncine] In SD Kipman (ed.) Manifeste pour la<br \/>\nm\u00e9decine de la personne [Manifesto for Person<br \/>\nCentered Medicine]. Paris, Dunod, 2012<br \/>\n9.\t La\u00edn-Entralgo P. El Diagn\u00a9stico M\u00e9dico: His-<br \/>\ntoria y Teor\u00eda [The medical diagnostic: history<br \/>\nand theory]. Salvat, Barcelona, 1982<br \/>\n10.\tBotbol M, Lecic-Tosevski D. Person-Centered<br \/>\nMedicine and Subjectivity. In: Jeffrey HD Cor-<br \/>\nnelius-White, Renate Motschnig- Pitrik, Mi-<br \/>\nchael Lux (eds) Interdisciplinary Applications of<br \/>\nthe Person-Centered Approach. Springer, New<br \/>\nYork, 2013<br \/>\n11.\tBotbol M, Lecic-Tosevski D. Subjectivity Inter-<br \/>\nsubjectivity and Psychological Functioning, In<br \/>\nPerson Centered Psychiatry. Springer, Heidel-<br \/>\nberg, in press, 2015<br \/>\n12.\tLebovici S. L\u2019arbre de vie \u2013 \u00e9l\u00e9ments de la psy-<br \/>\nchopathologie du b\u00e9b\u00e9 [The tree of life \u2013 Princi-<br \/>\nples of infant psychopathology]. Eres, Toulouse,<br \/>\n1999<br \/>\n13.\tHochmann J. Une histoire de l\u2019empathie [A his-<br \/>\ntory of empathy]. Odile Jacob, Paris, 2012<br \/>\n14.\tRicoeur P. Temps et r\u00e9cit [Time and narrative].<br \/>\nLe Seuil, Paris,1983<br \/>\n15.\tKleinman A.The Illness Narratives. Basic Book,<br \/>\nNew York, 1988<br \/>\n16.\tRicoeur P. La souffrance n\u2019est pas la douleur<br \/>\n[Suffering is not Pain]. Psychiatrie Fran\u00e7aise,<br \/>\nJuin 1992<br \/>\n17.\tBotbol M, Hagmann V. Douleur ou souffrance?<br \/>\nA propos du point de vue de Paul Ricoeur. [Suf-<br \/>\nfering or Pain\u00a0 ? on Paul Ricoeur perspective]<br \/>\nNervure 2005; 17: 2<br \/>\n18.\tLoas G. L\u2019Alexithymie [Alexithymia]. Annales<br \/>\nmedico-psychologiques 2010; 168: 712-715<br \/>\n19.\tSifneos PE.The prevalence of Alexithymic char-<br \/>\nacteristics in psychosomatic patients. Psycho-<br \/>\ntherapy and Psychosomatics 1973; 22: 255-26<br \/>\n20.\tFeldman-Hall O, Dalgleish T, Mobbs D. Alex-<br \/>\nithymia decreases altruism in real social deci-<br \/>\nsions. Cortex 2012; 49: 899-90<br \/>\n21.\tTaylor GJ, Bagby MR, Parker JDA. Disorders of<br \/>\nAffect Regulation: Alexithymia in Medical and<br \/>\nPsychiatric Illness. Cambridge University Press,<br \/>\n1999<br \/>\nProf. Michel Botbol,<br \/>\nProfessor of Child and Adolescent Psychiatry<br \/>\nat University of Western Brittany,<br \/>\nChief of the Child and Adolescent<br \/>\nDepartment of Brest University Hospital<br \/>\nMember of the Board of the International<br \/>\nCollege for Person Centered Medicine<br \/>\nChair of the Psychoanalysis in<br \/>\nPsychiatry WPA Section<br \/>\nE-mail: botbolmichel@orange.fr<br \/>\nIntroduction<br \/>\nAncient as well as modern concepts of<br \/>\n\u201chealth\u201d have highlighted the holistic un-<br \/>\nderstanding (emphasizing the importance<br \/>\nof the whole and the interdependence of its<br \/>\nparts) in medicine. Ancient Chinese medi-<br \/>\ncine used diagnostic indicators in a holistic<br \/>\nframework to provide an understanding of<br \/>\nthe disease process. The Indian medicine<br \/>\nAyurveda (or the knowledge of living),<br \/>\nviewed health as harmony between body,<br \/>\nmind and spirit. Ancient Greek philoso-<br \/>\nphers affirmed that \u201cif the whole is not well,<br \/>\nit is impossible for the part to be well\u201d [1, 2].<br \/>\nA modern articulation of this understand-<br \/>\ning is expressed in the World Health Or-<br \/>\nganization (WHO) constitution published<br \/>\nin 1946 which defined health as \u201ca state of<br \/>\ncomplete physical, emotional, and social well-<br \/>\nbeing and not merely the absence of disease or<br \/>\ninfirmity.\u201d\u00a0[3]<br \/>\nThe extraordinary advances in medicine<br \/>\npost World War II, with its emphasis on<br \/>\nspecialized care, resulted in the provision<br \/>\nof medical care unimaginable only a few<br \/>\ndecades ago, especially for complex and ad-<br \/>\nvanced medical-surgical problems.This em-<br \/>\nphasis and the current progress has changed<br \/>\nour expectations of medicine and has in-<br \/>\ncreased hope in prolonging life and improv-<br \/>\ning the quality of life for people suffering<br \/>\nfrom these ailments, an obvious example<br \/>\nbeing the field of organ transplantation. On<br \/>\nthe other hand, the focus on disease special-<br \/>\nization has led to an unfortunate shift in<br \/>\nthe practice of medicine away from a view<br \/>\nof health as an interdependent whole with<br \/>\nartificially parceling out care, resulting in<br \/>\nfragmentation, incoordination, and in some<br \/>\ninstances decreased access to care.<br \/>\nFurthermore, the worldwide increased<br \/>\nprevalence of non-communicable chronic<br \/>\ndiseases, the interconnectedness and ex-<br \/>\nceptional burden of chronic diseases and<br \/>\nmental health conditions, along with the<br \/>\nkey role of behavioral determinant of health<br \/>\nstrongly demand models of care that ad-<br \/>\ndress the totality of health with emphasis<br \/>\non disease prevention and health restora-<br \/>\ntion. In this paper, we will review the ra-<br \/>\ntional for integrating mental health within<br \/>\nprimary care along with reported positive<br \/>\nexperiences in the field. We will also discuss<br \/>\nthe Person-centered Integrative Diagnosis<br \/>\n(PID) model, an emerging person- and pa-<br \/>\ntient-centered approach to care anchored in<br \/>\nperson-centered medicine.The PID consid-<br \/>\ners the person-in-context as the center and<br \/>\ngoal of interventions and care [4, 5].<br \/>\nWhy Integrate Mental Health<br \/>\nCare and Primary Care<br \/>\nThe need for integrated care is almost uni-<br \/>\nversally appreciated and it has risen from<br \/>\nthe recognition that specialized care often<br \/>\nleads to fragmentation of care, inadequacy<br \/>\nof addressing comorbid problems, limits ac-<br \/>\ncess to care and largely neglects preventive<br \/>\nefforts. In contrast to disease focused spe-<br \/>\ncialized and fragmented system approach<br \/>\nwith clear barriers to care, integrated care<br \/>\nis the systematic coordination of care for<br \/>\nphysical and mental disorders. It allows for<br \/>\nthe provision of adequate care for the whole<br \/>\nperson (addressing any presenting health-<br \/>\nrelated problems) facilitating a holistic ap-<br \/>\nproach to care.<br \/>\nMultiple lines of evidence point to the rel-<br \/>\nevance of this model for addressing mental<br \/>\nand physical disorders.There is a high prev-<br \/>\nalence of mental disorders among people<br \/>\npresenting to primary care settings. Like-<br \/>\nwise, people with mental disorders have<br \/>\nhigh rates of physical disorders.<br \/>\nMedical comorbidity is the most significant<br \/>\ncause of mortality in people with mental<br \/>\ndisorders, and these disorders are less likely<br \/>\nto receive adequate attention in non-inte-<br \/>\ngrated care systems. Patients with chronic<br \/>\nmental disorders such as major depression,<br \/>\nbipolar disorder, schizophrenia, alcoholism<br \/>\nand other substance use disorders have high<br \/>\nrates of physical disorders such as diabetes,<br \/>\ncardiovascular, chronic respiratory diseases,<br \/>\nhuman- immune deficiency virus (HIV) in-<br \/>\nIhsan M. Salloum<br \/>\nThe Integration of Mental Health and<br \/>\nPrimary Care: A Person-centered Approach<br \/>\nLadan Khazai<br \/>\nBACK TO CONTENTS<br \/>\n110 111<br \/>\nPerson Centered MedicinePerson Centered Medicine UNITED STATES OF AMERICAUNITED STATES OF AMERICA<br \/>\nthe availability of unified support systems<br \/>\nsuch as shared medical information and<br \/>\nreferral systems, the degree of shared goals<br \/>\nand vision among the health care teams and<br \/>\nthe degree of shared financing streams.<br \/>\nHealth services have been graded on a con-<br \/>\ntinuum of integration of care, from low to<br \/>\nfully integrated systems, based on the level<br \/>\nof collaboration between the various disci-<br \/>\nplines of health care providers. The lower<br \/>\nthe level of care, the less being able to ad-<br \/>\ndress more complex conditions. Level one<br \/>\nidentifies a low level of integration with<br \/>\nminimal collaboration between health pro-<br \/>\nfessionals. Level two identifies basic col-<br \/>\nlaboration and loosely coordinated care,<br \/>\nwith periodic communications between<br \/>\nhealth providers in separate systems of care<br \/>\nand separate locations. Level three refers<br \/>\nto closer collaboration among health pro-<br \/>\nviders who still are part of different teams<br \/>\nbut share the same facility (co-located).The<br \/>\nco-location facilitates more frequent com-<br \/>\nmunications,including occasional meetings.<br \/>\nLevel four identifies close collaboration in<br \/>\na setting where there is partial integration<br \/>\nbetween mental health and other medical<br \/>\ncare. Providers are co-located at the same<br \/>\nsites and share other functions such as the<br \/>\nmedical information system or scheduling.<br \/>\nThere is more formal collaborative work<br \/>\nand meetings that may involve coordinated<br \/>\ntreatment plans for certain cases. The most<br \/>\nintegrated level is level five. There is close<br \/>\ncollaboration in this fully integrated model<br \/>\nwhere health professionals operate as part<br \/>\nof the same team, with shared vision, and<br \/>\nusing the same supportive system. There is<br \/>\nregular and systematic team meetings and<br \/>\ntreatment planning with similar emphasis<br \/>\nand expectations on prevention and treat-<br \/>\nment.<br \/>\nThe Four Quadrant Model is a conceptual<br \/>\npopulation-based planning model for in-<br \/>\ntegrated care developed under the auspices<br \/>\nof the National Council for Community<br \/>\nBehavioral Healthcare (NCCBH) [29].<br \/>\nHealth risk and complexity are considered<br \/>\nin each quadrant and used as a guide for in-<br \/>\nterventions and levels of services to meet the<br \/>\nindividual patient\u2019s need. Quadrants range<br \/>\nfrom low risk\/low complexity (quadrant I)<br \/>\nto high risk\/high complexity (quadrant IV)<br \/>\non both mental health\/substance abuse and<br \/>\nphysical health. Quadrant II indicates high<br \/>\nrisk\/complexity on mental health\/substance<br \/>\nabuse and low to moderate risk\/complexity<br \/>\non physical health; quadrant III indicates<br \/>\nlow to moderate risk\/complexity on men-<br \/>\ntal health substance abuse and high risk\/<br \/>\ncomplexity on physical health. The Care<br \/>\nModel is another conceptual model de-<br \/>\nveloped for improving care for chronic ill-<br \/>\nnesses by refocusing the emphasis from an<br \/>\nillness-centered reactive model to a health-<br \/>\ncentered preventative model. It addresses<br \/>\nkey features for enhancing care at multiple<br \/>\nlevels including community, organization,<br \/>\npractice and patient levels [29].<br \/>\nModels have been advanced for linking inte-<br \/>\ngrated care to the processes of care through<br \/>\nsystematic screening and identification of<br \/>\nmental and behavioral disorders. This pro-<br \/>\nvides targeted linkage to appropriate inter-<br \/>\nventions within an integrated primary care<br \/>\nproviders with the goals to enhance access<br \/>\nto care, reduce stigma, and enhance engage-<br \/>\nment and adherence to care [30].<br \/>\nAn example of systematic screening and<br \/>\nbrief intervention highly relevant to prima-<br \/>\nry care is the Screening, Brief Interventions,<br \/>\nReferral and Treatment (SBIRT) program<br \/>\nfor unhealthy alcohol use [31]. The SBIRT<br \/>\nis an evidence-based practice aimed at iden-<br \/>\ntifying, reducing and preventing problemat-<br \/>\nic alcohol use. The SBIRT has three major<br \/>\ncomponents: Screening, using highly effi-<br \/>\ncient and practical standardized screening<br \/>\ntools such as the CAGE questionnaire, the<br \/>\nAlcohol Use Identification test (AUDIT)<br \/>\nor the three questions AUDIT-C [32\u201334].<br \/>\nBrief Intervention, providing feedback and<br \/>\nadvice for patients with unhealthy alcohol<br \/>\nuse. Referral to Treatment, for either brief<br \/>\ntherapy or for additional more intensive<br \/>\ntreatment. Similarly, interventions for the<br \/>\nhighly prevalent depression in primary care<br \/>\nhave been developed and extensively tested<br \/>\n[35]. Community friendly interventions<br \/>\nthat could be incorporated into integrated<br \/>\nprimary care programs for serious mental<br \/>\ndisorders are less developed. Two examples<br \/>\nof integrated counseling interventions for<br \/>\nbipolar disorder with comorbid alcohol or<br \/>\nsubstance use that are designed to be simple<br \/>\nand easily adaptable to community settings<br \/>\ninclude a group therapy format [36] and<br \/>\nan individual counseling approach [37].<br \/>\nThese interventions utilize integrated dis-<br \/>\nease management and educational strate-<br \/>\ngies along with motivational enhancement<br \/>\napproaches that are practical and easily ap-<br \/>\nplicable in community settings.<br \/>\nThe Person-centered Integrative<br \/>\nDiagnosis (PID) Model<br \/>\nThe Person-centered Integrative Diagno-<br \/>\nsis model (PID) may provide a conceptual<br \/>\napproach to integrative care. The emerging<br \/>\nPID model aims at putting into practice the<br \/>\nvision of Person-centered Medicine affirm-<br \/>\ning the whole person of the patient in con-<br \/>\ntext as the center of clinical care and health<br \/>\npromotion at the individual and community<br \/>\nlevels [4,5].The PID motto of \u201cpersons car-<br \/>\ning for persons\u201d recognizes that the person<br \/>\nof the patient and the person of the health<br \/>\nproviders are in a respectful and empower-<br \/>\ning partnership. The PID considers the to-<br \/>\ntality of the person\u2019s health, including both<br \/>\nill health and positive aspects of health with<br \/>\nprimary emphasis on prevention and health<br \/>\nrestoration. It is based on a holistic, contex-<br \/>\ntual and humanistic approach to care em-<br \/>\nphasizing recovery and wellbeing. It views<br \/>\nthe process of care as a partnership (equali-<br \/>\ntarian) approach, including the patient,<br \/>\nfamily, care givers and other stakehold-<br \/>\ners and the health professionals forming a<br \/>\nhealth support network.<br \/>\nThe PID scheme could be easily incorporat-<br \/>\ned into other models of integrated care, and<br \/>\nit provides a comprehensive and dynamic<br \/>\nfection, Hepatitis, sexually transmitted dis-<br \/>\neases (STD), tuberculosis (TB) and trauma<br \/>\nwith excess mortality. Factors that increase<br \/>\nrisk for physical disorders in mental dis-<br \/>\norders include high rates of smoking, sub-<br \/>\nstance abuse, and obesity [6]. Studies have<br \/>\nshown that those with serious mental illness<br \/>\nhave 25 years less life expectancy compared<br \/>\nto the general population [7]. They are over<br \/>\nthree times more likely to die from cardiac<br \/>\ndiseases and over six times more likely to<br \/>\ndie from respiratory ailments. These pa-<br \/>\ntients often suffer from multi-comorbid<br \/>\nproblems. For example, patients with bipo-<br \/>\nlar disorder have high rates of cardiovascu-<br \/>\nlar and respiratory diseases, in addition to<br \/>\nsubstance use disorders which increase their<br \/>\nrisk for chronic infectious diseases such as<br \/>\nviral hepatitis and HIV infection [8, 9].<br \/>\nThree or more chronic comorbid conditions<br \/>\nwere found, on the average, among people<br \/>\nwith bipolar disorder [10]. Additional co-<br \/>\nmorbidity increases the risk for mortality.In<br \/>\na study of mortality among Medicaid ben-<br \/>\neficiaries, while the most common causes<br \/>\nof death were attributed to heart disease<br \/>\nand cancer, death by injury was found to<br \/>\nbe twice as likely among the mentally ill<br \/>\ncompared to the general population. Those<br \/>\nwith mental illness and comorbid substance<br \/>\nabuse were 6-8 times more likely to die of<br \/>\ninjury,primarily poisoning,than their coun-<br \/>\nterparts treated for medical conditions only<br \/>\n[11]. While that study did not look at the<br \/>\ntrajectory of care for those patients, limited<br \/>\naccess to appropriate care may have been a<br \/>\nkey contributing factor for those with excess<br \/>\nmortality. Integrated care will substantially<br \/>\nfacilitates access to care for patients with<br \/>\nsevere mental disorders.<br \/>\nThe need for integrated care stems from an<br \/>\neven more fundamental reason for a holistic<br \/>\nview of health. Studies have long reported<br \/>\nthat psychosocial determinants generate<br \/>\nthe majority of health care visits [12]. Psy-<br \/>\nchosocial distress or depressive disorders<br \/>\noften are expressed as physical distress seen<br \/>\nby primary care physicians. Likewise, de-<br \/>\npression may develop as a consequence of<br \/>\nchronic physical disorder such as diabetes or<br \/>\ncardiovascular disorder [13]. Furthermore,<br \/>\nbehavioral and life style factors are overrep-<br \/>\nresented among the preventable risk factor<br \/>\nfor developing chronic diseases. The World<br \/>\nHealth Alliance (World Medical Asso-<br \/>\nciation, International Council of Nurses,<br \/>\nWorld Dental Federation, and Internation-<br \/>\nal Pharmaceutical Federation) has recently<br \/>\nidentified through a Health Improvement<br \/>\nCard a number of key risk factors to pre-<br \/>\nvent chronic diseases. Among these are diet,<br \/>\nexercise, avoidance of alcohol and other<br \/>\nhazardous drugs, stress-control, adequate<br \/>\nrest and sleep, and participation in social<br \/>\nand creative activities [14]. Addressing be-<br \/>\nhavioral health problems in primary care is<br \/>\nessential because of the prevalence of these<br \/>\nproblems in primary care setting with re-<br \/>\nported prevalence of smoking at 20%, obe-<br \/>\nsity at 30% and sedentary lifestyle at 50%.<br \/>\nChronic conditions that require a behav-<br \/>\nioral health component in a standard care<br \/>\nprotocol include asthma, diabetes, cardio-<br \/>\nvascular disease, irritable bowel syndrome,<br \/>\nobesity and substance abuse. Alcohol abuse<br \/>\nis linked to over 60 medical disorders [15].<br \/>\nPrimary care practices are de facto where<br \/>\nthe overwhelming majority of patients with<br \/>\nmental health problems receive care [16].<br \/>\nThere is mounting empirical evidence dem-<br \/>\nonstrating that integrated care improves<br \/>\naccess to both mental health and physical<br \/>\nhealth services, decrease stigma of receiving<br \/>\nmental health care, improves outcome and<br \/>\nreduces health care costs [17\u201325].<br \/>\nThe importance of integrating mental<br \/>\nhealth into general health and public health<br \/>\npractice has been recognized as a way for<br \/>\npromoting mental health [26]. Integration<br \/>\nof mental health and substance use disor-<br \/>\nders treatment in primary care has been also<br \/>\nsupported by legislative acts, such as the Pa-<br \/>\ntient Protection and Affordable Care Act of<br \/>\n2014 in the United States of America and<br \/>\nhave been highlighted by the US Surgeon<br \/>\nGeneral and the Institute of Medicine re-<br \/>\nports [27, 28].<br \/>\nLevels and Models of<br \/>\nIntegrated Care<br \/>\nIntegration may need to be addressed at<br \/>\nmultiple levels. At the systems\u2019 level, major<br \/>\nfactors such as financing of care and facili-<br \/>\ntating access to care need to be addressed<br \/>\nto facilitate integration. At the providers\u2019<br \/>\nlevel\u00ad, training and commitment are es-<br \/>\nsential. For example, integrating mental<br \/>\nhealth and substance abuse treatment into<br \/>\nprimary care there is a need for a three-<br \/>\nway enhancement of training. Medical care<br \/>\nproviders need to have enhanced training in<br \/>\nmental health and substance abuse recogni-<br \/>\ntion and need for intervention. Likewise,<br \/>\nmental health and substance abuse provid-<br \/>\ners need to have enhanced training in the<br \/>\nrecognition and need for intervention for<br \/>\nmedical, mental health or substance abuse<br \/>\nproblems. At the interventions\u2019 level there<br \/>\nis a need to identify, select, and develop in-<br \/>\ntegrated pharmacological or psychosocial<br \/>\ninterventions that are most appropriate for<br \/>\nthe patient. Repeated studies have high-<br \/>\nlighted the superiority of integrated inter-<br \/>\nventions, tailored to the patient\u2019s comorbid<br \/>\nconditions, compared to interventions that<br \/>\nare condition specific. These studies high-<br \/>\nlight the importance of addressing the dy-<br \/>\nnamic interplay between comorbid condi-<br \/>\ntions and their reciprocal negative impacts<br \/>\non the overall outcome. Patients\u2019 factors<br \/>\nis another crucial factor for integration of<br \/>\ncare, especially with the increased patient\u2019s<br \/>\nawareness and participatory, protagonist<br \/>\nrole in the process of care. This involves<br \/>\nenhanced patients\u2019 recognition of interrela-<br \/>\ntionship of health problems and enhanced<br \/>\ncommitment to wellness maintenance and<br \/>\nhealth restoration [5, 8].<br \/>\nIntegration of care between different service<br \/>\nproviders is facilitated by addressing a num-<br \/>\nber of features. These include the level of<br \/>\ncommunication between the services, their<br \/>\nphysical proximity (co-located or not), their<br \/>\naccessibility to patients in terms of distance<br \/>\nand time for the appointment, the availabil-<br \/>\nity of expertise and cross-trained personnel,<br \/>\nBACK TO CONTENTS<br \/>\n112 113<br \/>\nPerson Centered Medicine Person Centered MedicineUNITED STATES OF AMERICAUNITED STATES OF AMERICA<br \/>\n20.\tLemmens LC, Molema CC, Versnel N, Baan<br \/>\nCA, de Bruin SR. Integrated care programs for<br \/>\npatients with psychological comorbidity: A sys-<br \/>\ntematic review and meta-analysis. J Psychosom<br \/>\nRes, 2015.<br \/>\n21.\tOuwens M, Wollersheim H, Hermens R, Huls-<br \/>\ncher M, Grol R. Integrated care programmes for<br \/>\nchronically ill patients: a review of systematic re-<br \/>\nviews. International journal for quality in health<br \/>\ncare, 2005;17(2):141-6.<br \/>\n22.\tKilbourne AM, Greenwald DE, Bauer MS,<br \/>\nCharns MP, Yano EM. Mental health provider<br \/>\nperspectives regarding integrated medical care<br \/>\nfor patients with serious mental illness. Adm<br \/>\nPolicy Ment Health, 2012;39(6):448-57.<br \/>\n23.\tLawrence D, Kisely S. Inequalities in healthcare<br \/>\nprovision for people with severe mental illness. J<br \/>\nPsychopharmacol, 2010;24(4 Suppl):61-8.<br \/>\n24.\tWittwer SD. The patient experience with the<br \/>\nmental health system: a focus on integrated<br \/>\ncare solutions. J Manag Care Pharm, 2006;12(2<br \/>\nSuppl):21-3.<br \/>\n25.\tAHRQ. Integration of Mental Health\/Sub-<br \/>\nstance Abuse and Primary Care. Structured Ab-<br \/>\nstract. Rockville, MD.: Agency for Healthcare<br \/>\nResearch and Quality, October 2008.<br \/>\n26.\tHerman H, Saxena S, Moodie R. Promoting<br \/>\nmental health: concepts, emerging evidence,<br \/>\npractice. WHO, 2005.<br \/>\n27.\tMental Health: A Report of the Surgeon Gen-<br \/>\neral (1999) Office of the Surgeon General of the<br \/>\nUnited States.<br \/>\n28.\tReport TIoM. Building a Better Delivery Sys-<br \/>\ntem: A New Engineering\/Health Care Partner-<br \/>\nship (2005). Washington, DC.<br \/>\n29.\tNASMHPD. Integrating Behavioral Health<br \/>\nand Primary Care Services: Opportunities and<br \/>\nChallenges for State Mental Health Authorities.<br \/>\nAlexandria VA: National Association of State<br \/>\nMental Health Program Directors. Medical<br \/>\nDirectors Council January, 2005 Contract No.:<br \/>\nEleventh<br \/>\n30.\tButler M, Kane RL, McAlpine D, Kathol RG,<br \/>\nFu SS, Hagedorn H, et al. Integration of mental<br \/>\nhealth\/substance abuse and primary care. 2008.<br \/>\n31.\tMadras BK,Compton WM,Avula D,Stegbauer<br \/>\nT, Stein JB, Clark HW. Screening, brief inter-<br \/>\nventions,referral to treatment (SBIRT) for illicit<br \/>\ndrug and alcohol use at multiple healthcare sites:<br \/>\ncomparison at intake and 6 months later. Drug<br \/>\nAlcohol Depend, 2009;99(1-3):280-95.<br \/>\n32.\tBohn MJ, Babor TF, Kranzler HR. The Alco-<br \/>\nhol Use Disorders Identification Test (AUDIT):<br \/>\nvalidation of a screening instrument for use in<br \/>\nmedical settings. Journal of studies on alcohol,<br \/>\n1995;56(4):423-32.<br \/>\n33.\tEwing JA. Detecting alcoholism: The cage ques-<br \/>\ntionnaire. JAMA, 1984;252(14):1905-7.<br \/>\n34.\tBush K, Kivlahan DR, McDonell MB, Fihn<br \/>\nSD, Bradley KA.The audit alcohol consumption<br \/>\nquestions (audit-c): An effective brief screen-<br \/>\ning test for problem drinking. Ambulatory Care<br \/>\nQuality Improvement Project.. Archives of In-<br \/>\nternal Medicine, 1998;158(16):1789-95.<br \/>\n35.\tdeGruy FV. Treatment of depression in primary<br \/>\ncare. Ann Fam Med, 2015;13(1):3-5.<br \/>\n36.\tWeiss RD, Griffin ML, Kolodziej ME, Green-<br \/>\nfield SF, Najavits LM, Daley DC, et al. A ran-<br \/>\ndomized trial of integrated group therapy versus<br \/>\ngroup drug counseling for patients with bipolar<br \/>\ndisorder and substance dependence. American<br \/>\nJournal of Psychiatry, 2007;164(1):100-7.<br \/>\n37.\tSalloum IM, Douaihy AB, Daley DC, Kelly<br \/>\nTM, Cornelius JR, Kirisci L. Integrated individ-<br \/>\nual therapy for bipolar disorder and alcoholism:<br \/>\nresults from a randomized pilot study. Bipolar<br \/>\nDisorders, 2009;11:74-5.<br \/>\n38.\tSalloum IM, Mezzich JE. Person-centered di-<br \/>\nagnosis. Int J Integr Care, 2010;10 Suppl:e027.<br \/>\n39.\tSalloum IM,Mezzich JE.Outlining the bases of<br \/>\nperson-centred integrative diagnosis. Journal of<br \/>\nevaluation in clinical practice 2011;17(2):354-6.<br \/>\n40.\tMezzich JE, Snaedal J, van Weel C, Botbol M,<br \/>\nSalloum I. Introduction to person-centred med-<br \/>\nicine: from concepts to practice. Journal of Eval-<br \/>\nuation in Clinical Practice, 2011;17(2):330-2.<br \/>\nIhsan M. Salloum, MD,<br \/>\nMPHProfessor of Psychiatry<br \/>\nUniversity of Miami, Miller<br \/>\nSchool of Medicine<br \/>\nExecutive Board Member, International<br \/>\nCollege of Person-centered Medicine;<br \/>\nChair, Section on Classification, Diagnostic<br \/>\nAssessment and Nomenclature,<br \/>\nWorld Psychiatric Association<br \/>\nLadan Khazai, MD, Master of Public<br \/>\nHealth Graduate Candidate, 2016;<br \/>\nDepartment of Public Health<br \/>\nSciences, Research Assistant,<br \/>\nDepartment of Psychiatry and<br \/>\nBehavioral Sciences,<br \/>\nUniversity of Miami, Miller<br \/>\nSchool of Medicine<br \/>\nCorresponding address:<br \/>\nIhsan\u00a0M.\u00a0Salloum, MD, MPH<br \/>\n1120 NW 14th<br \/>\nStreet, suite 1449,<br \/>\nMiami, Florida 33136, USA.<br \/>\nE-mail: isalloum@med.miami.edu<br \/>\nassessment of the health status of the person<br \/>\npresenting for care. The PID is a multilevel<br \/>\napproach to assessing the health status. The<br \/>\nfirst level includes the assessment of health.<br \/>\nThis includes the assessment of ill health,<br \/>\nsuch as any physical or mental disorders<br \/>\nalong with assessment of functional abili-<br \/>\nties. This level also includes the assessment<br \/>\nof positive aspects of health and wellbeing.<br \/>\nPositive aspects of health and wellbeing are<br \/>\nkey to the recovery, health restoration and<br \/>\nhealth preservation efforts.The second level<br \/>\nin the PID is the assessment of contributors<br \/>\nto the health status. These contributors are<br \/>\nconsidered on a bio-psycho-social continu-<br \/>\num. Contributors to health are divided into<br \/>\nhealth promoters and health risks.The PID<br \/>\nhas incorporated the health contributors<br \/>\nincluded in the Health Improvement Card<br \/>\ndeveloped by the World Health Professions<br \/>\nAlliance [14]. Health promoters include<br \/>\ndiet, physical activity, creative activity, social<br \/>\ninvolvement,and other.Health risks include<br \/>\noverweight, elevated lipid, elevated glucose,<br \/>\nhigh blood pressure, alcohol and tabacco<br \/>\nuse, family history, early trauma, significant<br \/>\nstress, and other. The third level of the PID<br \/>\nis the experience of health which includes<br \/>\nthe experience of wellbieng and the experi-<br \/>\nence of ill health. This provides assessment<br \/>\nof personal and cultural identity, suffering,<br \/>\nmeaning of illness and expectations for the<br \/>\nhealth care encounter.These subjective con-<br \/>\ntributions to the process of diagnosis and<br \/>\ncare provide idiographic narrative crucial<br \/>\nfor the processes of empowerment, engage-<br \/>\nment, partnership and recovery [38\u201340].<br \/>\nFuture Directions<br \/>\nIntegration of care has become a pressing<br \/>\nprerogative to provide an adequate response<br \/>\nto the growing pandemic of chronic diseas-<br \/>\nes and to the increase of the aging world-<br \/>\npopulation with substantial rise of the bur-<br \/>\nden of comorbid chronic conditions. The<br \/>\nintegration of mental health into primary<br \/>\ncare and general health responds to the<br \/>\nconsiderable evidence of the strong impact<br \/>\nof mental and behavioral health on physical<br \/>\nhealth, and also to the need for adequately<br \/>\naddressing ill physical health in people with<br \/>\nmental health problems. The dictate that<br \/>\n\u201cthere is no health without mental health\u201d and<br \/>\nthe goal of eliminating disparities in health<br \/>\ncare are best served by integration of care.<br \/>\nRefocusing medicine from an essentially<br \/>\ndisease-centered, \u201creactive\u201d attitude to an<br \/>\napproach focusing on disease prevention<br \/>\nand health restoration with emphasis on<br \/>\nenhancing wellbeing and healthy living also<br \/>\ncalls for integration of care.<br \/>\nThe Person-centered Integrative Diagnosis<br \/>\napproach, embodying the vision of Person-<br \/>\ncentered Medicine as expressed to a large<br \/>\nextent in the various Geneva Declarations<br \/>\nand proceedings of the International Col-<br \/>\nlege of Person-centered Medicine (ICP-<br \/>\nCM), provides an overarching conceptual<br \/>\nframework for integrated care converging<br \/>\non the person in context as the center and<br \/>\ngoal of care and public health.<br \/>\nReferences<br \/>\n1.\t Christodoulou GN. (1987) Psychosomatic med-<br \/>\nicine. New York Plenum Press, NY<br \/>\n2.\t Plato. Harmidis Dialogue. 156 E. Athens: Papy-<br \/>\nros editions, 1975.<br \/>\n3.\t WHO. WHO Constitution. World Health Or-<br \/>\nganization, 1946.<br \/>\n4.\t Mezzich JE, Salloum IM, Cloninger CR, Salva-<br \/>\ndor-Carulla L, Kirmayer LJ, Banzato CEM, et<br \/>\nal. Person-centred integrative diagnosis: concep-<br \/>\ntual bases and structural model. Canadian Jour-<br \/>\nnal of Psychiatry, 2010;55(11):701-8.<br \/>\n5.\t Salloum IM, Mezzich JE. Conceptual appraisal<br \/>\nof the Person-centered Integrative Diagnosis<br \/>\nModel. International Journal of Person Cen-<br \/>\ntered Medicine, 2011;1(1):39-42.<br \/>\n6.\t De Hert M, Correll CU, Bobes J, Cetkovich-<br \/>\nBakmas M, Cohen D, Asai I, et al. Physical<br \/>\nillness in patients with severe mental disorders.<br \/>\nI. prevalence, impact of medications and dis-<br \/>\nparities in health care. World Psychiatry: official<br \/>\njournal of the World Psychiatric Association,<br \/>\n2011;10:52-77.<br \/>\n7.\t Parks J,Svendsen D,Singer P,Foti ME.Morbid-<br \/>\nity and Mortality in People with Serious Mental<br \/>\nIllness. Alexandria, VA: National Association of<br \/>\nState Mental Health Program Directors, 2006.<br \/>\n8.\t Salloum IM, Williams L, Douaihy A. Diagnos-<br \/>\ntic and Treatment Considerations: Bipolar Pa-<br \/>\ntients with Comorbid Substance Use Disorders.<br \/>\nPsychiatric Annals, 2008; 38(11):716-23.<br \/>\n9.\t Prieto ML, McElroy SL, Hayes SN, Sutor<br \/>\nB, Kung S, Bobo WV, et al. Association be-<br \/>\ntween history of psychosis and cardiovascular<br \/>\ndisease in bipolar disorder. Bipolar Disorder,<br \/>\n2015;17(5):518-27.<br \/>\n10.\tCarney CP, Jones LE. Medical comorbidity in<br \/>\nwomen and men with bipolar disorders: a pop-<br \/>\nulation-based controlled study. Psychosom Med,<br \/>\n2006;68(5):684-91.<br \/>\n11.\tDickey B, Dembling B, Azeni H, Normand<br \/>\nS-LT. Externally caused deaths for adults with<br \/>\nsubstance use and mental disorders. Journal<br \/>\nof Behavioral Health Services &#038; Research,<br \/>\n2004;31(1):75-85.<br \/>\n12.\tShapiro S, Skinner EA, Kramer M, Steinwachs<br \/>\nDM, Regier DA. Measuring need for mental<br \/>\nhealth services in a general population. Med<br \/>\nCare, 1985;23(9):1033-43.<br \/>\n13.\tDucat L, Rubenstein A, Philipson LH, An-<br \/>\nderson BJ. A review of the mental health is-<br \/>\nsues of diabetes conference. Diabetes Care,<br \/>\n2015;38(2):333-8.<br \/>\n14.\tSeyer J. Development of the Health Improve-<br \/>\nment Card developed by the World Health Pro-<br \/>\nfessions Alliance. (2012) In: Medicine ICoPC<br \/>\n(ed.) The 5th Geneva Conference on Person-<br \/>\ncentered Medicine. Geneva, Switzerland,.<br \/>\n15.\tGoldberg D.Psychiatry and primary care.World<br \/>\npsychiatry: official journal of the World Psychi-<br \/>\natric Association, 2003;2(3):153-7.<br \/>\n16.\tRegier DA, Narrow WE, Rae DS, Mandersc-<br \/>\nheid RW, Locke BZ, Goodwin FK.The de facto<br \/>\nUS mental and addictive disorders service sys-<br \/>\ntem. Epidemiologic catchment area prospective<br \/>\n1-year prevalence rates of disorders and services.<br \/>\nArch Gen Psychiatry, 1993;50(2):85-94.<br \/>\n17.\tWoltmann E, Grogan-Kaylor A, Perron B,<br \/>\nGeorges H, Kilbourne AM, Bauer MS. Com-<br \/>\nparative effectiveness of collaborative chronic<br \/>\ncare models for mental health conditions across<br \/>\nprimary,specialty,and behavioral health care set-<br \/>\ntings: systematic review and meta-analysis. Am J<br \/>\nPsychiatry, 2012;169(8):790-804.<br \/>\n18.\tKilbourne AM, Pirraglia PA, Lai Z, Bauer MS,<br \/>\nCharns MP, Greenwald D, et al. Quality of gen-<br \/>\neral medical care among patients with serious<br \/>\nmental illness: does colocation of services mat-<br \/>\nter? Psychiatr Serv, 2011;62(8):922-8.<br \/>\n19.\tDruss BG, von Esenwein SA, Compton MT,<br \/>\nRask KJ,Zhao L,Parker RM.A randomized tri-<br \/>\nal of medical care management for community<br \/>\nmental health settings: the Primary Care Access,<br \/>\nReferral, and Evaluation (PCARE) study. Am J<br \/>\nPsychiatry, 2010;167(2):151-9.<br \/>\nBACK TO CONTENTS<br \/>\n114 115<br \/>\nClimate ChangeClimate Change<br \/>\nClimate change is considered one of the<br \/>\ngreatest threats and\/or opportunities for<br \/>\n(human) health [1, 2, 11, 13]. Although<br \/>\nthe relationship between climate change<br \/>\nand health is complex, concrete examples<br \/>\ninclude extreme heat and weather events<br \/>\n[46], poor air quality exacerbating pulmo-<br \/>\nnary disease [47, 48], increased water-borne<br \/>\nand vector-borne infectious disease out-<br \/>\nbreaks and food insecurity and malnutrition<br \/>\ncaused by drought and crop failure.<br \/>\nDespite widespread recognition of the<br \/>\nnumerous health implications of climate<br \/>\nchange, evidence suggests that climate<br \/>\nchange continues relatively unabated [15].<br \/>\nIn this context, there is an imperative for<br \/>\nhealth professionals to be involved in the<br \/>\ndiscussion and act on this issue which<br \/>\nthreatens to undermine public health ef-<br \/>\nforts worldwide [2, 34, 35]. This paper<br \/>\nprovides a brief introduction to the United<br \/>\nNations Framework on Climate Change<br \/>\n(UNFCCC), current climate change ne-<br \/>\ngotiations and health sector engagement in<br \/>\nglobal efforts to tackle climate change.<br \/>\nI.The Climate-Health Nexus<br \/>\nBroad scientific evidence shows that climate<br \/>\nchange has and will continue to have pro-<br \/>\nfound health implications [2, 4], primar-<br \/>\nily driven by carbon and other greenhouse<br \/>\ngas emissions [16]. The effects of climate<br \/>\nchange on health are diverse and complex;<br \/>\nsome directly attributable to rising tem-<br \/>\nperatures and changes in precipitation pat-<br \/>\nterns, others are mediated through social<br \/>\nand ecological changes such as population<br \/>\ndisplacement, vector migration, conflict and<br \/>\nagricultural failure [7, 8, 14].<br \/>\nIn 2014, the Intergovernmental Panel on<br \/>\nClimate Change (IPCC) highlighted some<br \/>\nof the most significant threats to human<br \/>\nhealth posed by climate change including<br \/>\nbut not limited to:<br \/>\n\u2022\t Spread of infectious diseases including ma-<br \/>\nlaria,dengue fever,and water-borne diseases;<br \/>\n\u2022\t Increased frequency and severity of natu-<br \/>\nral disasters and flooding;<br \/>\n\u2022\t Worsening food insecurity;<br \/>\n\u2022\t Increased migration and conflict; and<br \/>\n\u2022\t More than 7 million deaths annually at-<br \/>\ntributable to rising temperatures and air<br \/>\npollution [2].<br \/>\nThe Road to Paris: What is at Stake for<br \/>\nHealth in COP21 Negotiations?<br \/>\nMediating factors<br \/>\nSocial infrastructureEnvironmental<br \/>\nconditions<br \/>\nCLIMATE CHANGE<br \/>\n\u2022 Precipitation<br \/>\n\u2022 Heat<br \/>\n\u2022 Floods<br \/>\n\u2022 Storms<br \/>\nHEALTH IMPACT<br \/>\n\u2022 Undernutrition<br \/>\n\u2022 Drowning<br \/>\n\u2022 Heart disease<br \/>\n\u2022 Malaria<br \/>\nPublic health capability<br \/>\nand adaptation<br \/>\n\u2022 Warning systems<br \/>\n\u2022 Socioeconomic status<br \/>\n\u2022 Health and nutrition status<br \/>\n\u2022 Primary health care<br \/>\n\u2022 Geography<br \/>\n\u2022 Baseline weather<br \/>\n\u2022 Soil\/dust<br \/>\n\u2022 Vegetation<br \/>\n\u2022 Baseline air\/water<br \/>\nquality<br \/>\n\u2022 Food production distribution<br \/>\n\u2022 Mental stress<br \/>\nVia economic and social disruption<br \/>\nMediated through natural systems:<br \/>\n\u2022 Allergens<br \/>\n\u2022 Disease vectors<br \/>\n\u2022 Increase water\/air pollution<br \/>\nIndirect exposures<br \/>\nDirect exposures<br \/>\n\u2022 Flood damage<br \/>\n\u2022 Storm vulnerability<br \/>\n\u2022 Health stress<br \/>\nFigure 1.\u2002\u0007Diagram of the three exposure pathways through which climate change affects health [3]<br \/>\nClimate change has been recognized as one<br \/>\nof the many social determinants of health<br \/>\n[5, 6]. Not surprisingly, health implications<br \/>\nof climate change are inequitably distribut-<br \/>\ned worldwide, excessively affecting popula-<br \/>\ntions in low-and-middle income countries<br \/>\nand vulnerable populations around the<br \/>\nglobe [10, 18, 19, 49, 54].<br \/>\nSynergistic adaptation and mitigation<br \/>\nstrategies are widely viewed as necessary<br \/>\nto address climate change broadly and,<br \/>\nmore specifically, the resulting health ef-<br \/>\nfects. Mitigation strategies seek to prevent<br \/>\nor otherwise avert climate change, while<br \/>\nadaptation implies modifying systems in<br \/>\nresponse to the effects of climate change<br \/>\n[38]. Health impacts of climate change are<br \/>\nindeed mediated through the environmen-<br \/>\ntal conditions, the social infrastructure and<br \/>\nthe public health adaptation [3, 49]. As a<br \/>\nresult, mitigation and adaptation strate-<br \/>\ngies demand a multisectorial approach<br \/>\nwhich includes the health sector [9, 10, 12,<br \/>\n32,\u00a033].<br \/>\nII.The Road to Paris\/COP21<br \/>\nAdopted as part of the Rio Convention at<br \/>\nthe Rio Earth Summit in 1992, UNFCCC<br \/>\nentered into force in 1994 and now includes<br \/>\n196 parties [37]. Each year, the Conference<br \/>\nof Parties (COP) is convened to review<br \/>\nUNFCCC progress.<br \/>\nIn December 2014, COP20 was held in<br \/>\nLima,Peru,and resulted in the Lima call for<br \/>\nclimate action [20], a precursor to this year\u2019s<br \/>\nmuch anticipated COP21 negotiations.The<br \/>\nLima call for climate action represented the<br \/>\nfirst time parties revived the health effects<br \/>\nfrom Art. 1 of the Convention [37] and<br \/>\nrecognized the need to further assess the<br \/>\nhealth co-benefits of climate change miti-<br \/>\ngation.<br \/>\nA new ambitious agreement on climate<br \/>\nchange is anticipated this December at<br \/>\nCOP21 (\u201c2015 Paris Climate Conference\u201d)<br \/>\nFigure 2.\u2002\u0007Diagram of the Road to Paris<br \/>\nWorld Conference Center Bonn (ADP 2.9, June 2015)<br \/>\nBACK TO CONTENTS<br \/>\n116 117<br \/>\nClimate Change Climate Change<br \/>\n[50] and is expected to be an important step<br \/>\nin addressing this huge challenge for hu-<br \/>\nmanity. This agreement is meant to succeed<br \/>\nto the Kyoto Protocol [51, 52] in setting<br \/>\nvery ambitious long-term goals for address-<br \/>\ning climate change. High profile targets<br \/>\nmay include limiting global mean tempera-<br \/>\nture increase and carbon emissions. Current<br \/>\nlong term goals under discussion are: a max-<br \/>\nimum of a two degree temperature increase<br \/>\nand carbon neutrality by 2050.<br \/>\nSince 2011, the Ad Hoc Working Group<br \/>\non the Durban Platform for Enhanced Ac-<br \/>\ntion (ADP) has been meeting regularly to<br \/>\ndiscuss the post 2020 agreement as well as<br \/>\nthe pre-2020 ambitions needed to reach<br \/>\nthe long term goal(s). The mandate of the<br \/>\nADP is set to conclude in December 2015;<br \/>\nthus, several ADP meetings are scheduled<br \/>\nin 2015.<br \/>\nThe first ADP meeting of the year (ADP<br \/>\n2.8) took place in Geneva in February, 2015<br \/>\nwhere an early draft of the party-led negoti-<br \/>\nating text was created, the so-called Geneva<br \/>\nNegotiating Text [21]. This text, essentially<br \/>\na compilation of all possible components<br \/>\nparties would want to see in an agreement,<br \/>\nwas the first time that health co-benefits<br \/>\nwere recognized with preamble language<br \/>\ninitially tabled by Switzerland. At the con-<br \/>\nclusion of ADP 2.8, all parties agreed that<br \/>\nthis text would need to be streamlined in<br \/>\nthe months to come.<br \/>\nIn June 2015, ADP 2.9 convened at the<br \/>\nUNFCCC Headquarters in Bonn, Ger-<br \/>\nmany. Although ADP 2.9 was a much an-<br \/>\nticipated opportunity to refine the 90-page<br \/>\nGeneva Negotiating Text, little significant<br \/>\nprogress was made to streamline the docu-<br \/>\nment.Parties met and started the streamlin-<br \/>\ning process but only managed to reduce the<br \/>\nnegotiating text to 85 pages [22]; however,<br \/>\nprogress was made in defining the way for-<br \/>\nward and the Co-Chairs of the ADP will<br \/>\nproduce a tool which will facilitate the work<br \/>\nat the next session at the end of the month<br \/>\nof July [23, 24].<br \/>\nDespite the lackluster progress at ADP 2.9,<br \/>\nG7 leaders concurrently announced a com-<br \/>\nmitment to \u201c&#8230;a protocol, another legal in-<br \/>\nstrument or an agreed outcome with legal<br \/>\nforce\u201d under the UNFCCC in Paris includ-<br \/>\ning an explicit political commitment to the<br \/>\n\u201cglobal goal to hold the increase in global<br \/>\naverage temperature below 2\u00b0C\u201d [25,\u00a0 26].<br \/>\nHowever, this commitment was not reflect-<br \/>\ned in concurrent negotiations at ADP 2.9<br \/>\nin Bonn.<br \/>\nIn 2013, parties adopted a new approach<br \/>\nto climate change negotiations which in-<br \/>\ncludes submission of Intended Nationally<br \/>\nDetermined Contributions (INDCs) , or<br \/>\npost-2020 climate commitments and plans.<br \/>\nINDCs are expected to be submitted by<br \/>\nall countries and are intended to shape the<br \/>\nanticipated COP21 framework.In anticipa-<br \/>\ntion of COP21 and a new comprehensive<br \/>\ninternational climate agreement, parties<br \/>\nwill continue to unveil their INDCs in the<br \/>\nmonths to come [17]. At COP20, parties<br \/>\nagreed that INDCs would focus on reduc-<br \/>\ning emissions, although little additional<br \/>\nINDC guidance for parties was agreed<br \/>\nupon [53]. The next INDC deadline is cur-<br \/>\nrently 1 October 2015 with a synthesis re-<br \/>\nport from the Secretariat anticipated by 1<br \/>\nNovember 2015.<br \/>\nIII. Health Professionals and<br \/>\nClimate Change Negotiations<br \/>\nHealth is included in the first article of the<br \/>\nUNFCCC as an requiring action: \u201cAdverse<br \/>\neffects of climate change\u201d means changes in<br \/>\nthe physical environment or biota resulting<br \/>\nfrom climate change which have signifi-<br \/>\ncant deleterious effects on the composition,<br \/>\nresilience or productivity of natural and<br \/>\nmanaged ecosystems or on the operation<br \/>\nof socio-economic systems or on human<br \/>\nhealth and welfare.\u201d[37] The grave and om-<br \/>\nnipresent threat of climate change demands<br \/>\ncoordinated multisectoral action [27] and<br \/>\nthe health sector has the potential to unite<br \/>\nactors behind a shared well understood and<br \/>\ntangible common cause [2].<br \/>\nYet, the climate-health connection has not<br \/>\nbeen consistently recognized in UN process-<br \/>\nes including development of the post-2015<br \/>\ndevelopment agenda [38], and the health<br \/>\nsector\u00a0 \u2013 and physicians more specifically\u00a0 \u2013<br \/>\nhave only distantly been involved in climate<br \/>\nchange negotiations. In the current stream-<br \/>\nlined and consolidated Geneva Negotiating<br \/>\nText, health is highlighted only in the pre-<br \/>\namble: \u201cRecognizing that actions to address<br \/>\nclimate change simultaneously contribute to<br \/>\nthe attainment of the highest possible level<br \/>\nof health and that climate change policies<br \/>\nand health policies should be mutually sup-<br \/>\nportive.\u201d [21] It is, however, generally recog-<br \/>\nnized that health sector interventions both<br \/>\nmitigation and adaptation and that financial<br \/>\nresources will be flowing through climate<br \/>\ndedicated funds to the health sector. At a<br \/>\nminimum, given the relationship between<br \/>\nclimate change and health, the health sector<br \/>\nwill need to be ready to anticipate the effects<br \/>\nof climate change on the natural history of<br \/>\ndisease, distribution of illness and severity<br \/>\nof disease burden for vulnerable populations<br \/>\n[2]. It will be important to mitigate these ef-<br \/>\nfects while also working to change the fac-<br \/>\ntors leading to worse health outcomes and<br \/>\nsupporting smart public policy decisions to<br \/>\nimprove population health. Health care pro-<br \/>\nviders are uniquely positioned to assume a<br \/>\nleadership role through both education and<br \/>\nadvocacy to advance mitigation and adapta-<br \/>\ntion [14, 29, 30, 31].<br \/>\nIt is critical, however, that the health sec-<br \/>\ntor engages in development of the global<br \/>\nframework for climate change action\u00a0 \u2013<br \/>\nnamely, the anticipated COP21 agreement.<br \/>\nAs recommended by the recent Lancet<br \/>\nCommission report, this agreement should,<br \/>\nat a minimum, provide clear support and<br \/>\ndirection for countries transitioning to a<br \/>\nlow-carbon economy, a strong predictable<br \/>\ncarbon pricing mechanism and ensuring ac-<br \/>\ncess to renewable energy [2].<br \/>\nSpecific advocacy targets for health profes-<br \/>\nsionals and organizations could include [2]:<br \/>\n\u2022\t Urging negotiators and national policy-<br \/>\nmakers (both within and beyond Minis-<br \/>\ntries of Health) to ensure urgent, ambi-<br \/>\ntious binding action on climate change as<br \/>\nreflected in both national level commit-<br \/>\nments (INDCs) and the COP21 Paris<br \/>\nagreement;<br \/>\n\u2022\t Leveraging media to communicate the<br \/>\nhealth risks of climate change and health<br \/>\nco-benefits of mitigation and adaptation<br \/>\nas well as the need for emergent action;<br \/>\n\u2022\t Investing in climate-health research to<br \/>\nmore clearly define and measure the<br \/>\nhealth co-benefits of adaptation and mit-<br \/>\nigation; and<br \/>\n\u2022\t Supporting integration of climate change<br \/>\neducation into health professions curri-<br \/>\ncula.<br \/>\nOver the last several years, several interna-<br \/>\ntional health and health professions orga-<br \/>\nnizations [61] including the World Health<br \/>\nOrganization (WHO) [62],World Medical<br \/>\nAssociation (WMA) [34-36, 60], Global<br \/>\nClimate &#038; Health Alliance (GCHA) [31]<br \/>\nand International Federation of Medical<br \/>\nStudents\u2019 Associations (IFMSA) [57-9]<br \/>\nhave been engaging in UNFCCC processes<br \/>\nand negotiations.<br \/>\nHowever, the urgency and severity of the<br \/>\nthreat to health from climate change de-<br \/>\nmands further action and participation by<br \/>\nhealth professionals and organizations on a<br \/>\nlocal, national and global scale.<br \/>\nThere are a growing number of successful<br \/>\nexamples of health professional advocacy<br \/>\nfor policy change that recognizes the health<br \/>\nco-benefits of climate change mitigation<br \/>\nand adaptation. The divestment movement<br \/>\nhas been rapidly growing within the last<br \/>\nfew years and seeks to support the transi-<br \/>\ntion to a low-carbon economy through<br \/>\n\u201cdisruptive innovation\u201d [55]. Divestment is<br \/>\ngenerally defined to include the withdrawal<br \/>\nof all existing investments in fossil fuels and<br \/>\na commitment not to make any new in-<br \/>\nvestments. In some cases, divestment may<br \/>\nbe coupled with investment in renewable<br \/>\nenergy or similar more socially responsible<br \/>\nindustries. In 2014, the British Medical As-<br \/>\nsociation (BMA) passed a motion to divest<br \/>\nfrom the fossil fuel industry [40, 41, 13, 45].<br \/>\nOther national medical associations, aca-<br \/>\ndemic institutions and other organizations<br \/>\nare increasingly considering and adopt-<br \/>\ning similar divestment policies [42-44].<br \/>\nSimilarly, Health Care Without Harm,<br \/>\nan international coalition of hospitals and<br \/>\nhealth care systems, professions and other<br \/>\norganizations, has developed and executed<br \/>\nnumerous successful local, national and in-<br \/>\nternational advocacy campaigns around en-<br \/>\nvironmental health and justice\u00a0\u2013 including<br \/>\nclimate change [56].<br \/>\nIV. Conclusion<br \/>\nUnchecked climate change will inevitably<br \/>\nhave grave negative implications for health;<br \/>\nconversely, addressing climate change<br \/>\nthrough mitigation and adaptation presents<br \/>\nan extraordinary opportunity to protect<br \/>\nglobal health [2]. Without concerted global<br \/>\naction, climate change will continue to have<br \/>\nprofound negative effects, both directly and<br \/>\nindirectly, on the patients and communi-<br \/>\nties health professionals serve\u00a0\u2013 and global<br \/>\npopulation health more broadly. Many<br \/>\nhealth sector interventions addressing cli-<br \/>\nmate change are no-regret policies which<br \/>\neven without accounting for the benefits for<br \/>\nclimate change are valuable for the health<br \/>\nof population [2]: health professionals have<br \/>\na role to play in illustrating that to policy-<br \/>\nmakers.<br \/>\nIn this context, the medical community has<br \/>\na professional obligation to engage in an ef-<br \/>\nfective multisectoral global response to cli-<br \/>\nmate change and to ensure a strong climate<br \/>\nchange agreement [34, 35]. The urgency<br \/>\naround this action and engagement by<br \/>\nhealth professionals could not be stronger<br \/>\nin the coming months as ADP\/COP21 ne-<br \/>\ngotiations proceed down the \u201croad to Paris\u201d.<br \/>\nKeep up with upcoming COP21 negotiations<br \/>\nand the road to Paris on Twitter by following<br \/>\n@medwma and #COP21, #ADP2015, #Cli-<br \/>\nmateHealth.<br \/>\nReferences<br \/>\n1.\t Costello A et al. Managing the health effects<br \/>\nof climate change. The Lancet 2009; 373:1693.<br \/>\nAvailable at http:\/\/www.ucl.ac.uk\/global-<br \/>\nhealth\/project-pages\/lancet1\/ucl-lancet-cli-<br \/>\nmate-change.pdf<br \/>\n2.\t Watts N et al. Health and climate change:<br \/>\npolicy responses to protect public health. The<br \/>\nLancet 2015; Online First. Available at http:\/\/<br \/>\nwww.thelancet.com\/journals\/lancet\/article\/<br \/>\nPIIS0140-6736(15)60854-6\/fulltext#<br \/>\n3.\t Climate Change 2014: Impacts, Adaptation and<br \/>\nVulnerability. Intergovernmental Panel on Cli-<br \/>\nmate Change\u00a0\u2013 Working Group 2. 2014. Avail-<br \/>\nable at http:\/\/www.ipcc.ch\/report\/ar5\/wg2\/<br \/>\n4.\t .WHO Quantitative risk assessment of the ef-<br \/>\nfects of climate change on selected causes of<br \/>\ndeath,2030sand2050s.WorldHealthOrganiza-<br \/>\ntion 2014. Available at http:\/\/apps.who.int\/iris\/<br \/>\nbitstream\/10665\/134014\/1\/9789241507691_<br \/>\neng.pdf<br \/>\n5.\t WHO Closing the gap in a generation: Health<br \/>\nequity through action on the social determinants<br \/>\nof health. Commission on Social Determinants<br \/>\nof Health\/World Health Organization. 2008.<br \/>\nAvailable at http:\/\/whqlibdoc.who.int\/publica-<br \/>\ntions\/2008\/9789241563703_eng.pdf<br \/>\n6.\t Galvao L et al. Climate change and the social<br \/>\ndeterminants of health: two interlinked agen-<br \/>\ndas. Global Health Promotion 2009; 16(1)<br \/>\nSupp(1):81-84. Available at http:\/\/ped.sagepub.<br \/>\ncom\/content\/16\/1_suppl\/81.full.pdf+html<br \/>\n7.\t McMichael A. Globalization, Climate Change,<br \/>\nand Human Health. N Engl J Med. 2013;<br \/>\n368:1335-1343. Available at http:\/\/www.nejm.<br \/>\norg\/doi\/full\/10.1056\/NEJMra1109341<br \/>\n8.\t Franchini M &#038; Mannucci P. Impact on human<br \/>\nhealth of climate changes.Euro J Int Med.2015;<br \/>\n26(1):1-5. Available at http:\/\/www.ejinme.com\/<br \/>\narticle\/S0953-6205(14)00362-8\/abstract<br \/>\n9.\t Thomas F et al. Extended impacts of climate<br \/>\nchange on health and wellbeing. Environmental<br \/>\nScience &#038; Policy 2015; 44:271-278. Available at<br \/>\nhttp:\/\/www.sciencedirect.com\/science\/article\/<br \/>\npii\/S1462901114001671<br \/>\n10.\tHuang C et al. Constraints and Barriers to Pub-<br \/>\nlic Health Adaptation to Climate Change. Am<br \/>\nJ Preventive Med. 2011; 40(2):183-190. Avail-<br \/>\nable at http:\/\/www.sciencedirect.com\/science\/<br \/>\narticle\/pii\/S0749379710006355<br \/>\n11.\tMcMichael A. Insights from past millennia into<br \/>\nclimatic impacts on human health and survival.<br \/>\nBACK TO CONTENTS<br \/>\n118 119<br \/>\nUNITED STATES OF AMERICA Person Centered MedicineClimate Change<br \/>\nPNAS 2012; 109(13):4730-4737. Available at<br \/>\nhttp:\/\/www.pnas.org.proxy-hs.researchport.<br \/>\numd.edu\/content\/109\/13\/4730.full.pdf+html<br \/>\n12.\tMcMichael T et al. Health risks, present and<br \/>\nfuture, from global climate change. BMJ 2012;<br \/>\n344:e1359. Available at http:\/\/www.bmj.com\/<br \/>\ncontent\/344\/bmj.e1359.full.pdf+html<br \/>\n13.\tMcCoy D et al. Climate change and human sur-<br \/>\nvival. BMJ 2014; 348:g2351. Available at http:\/\/<br \/>\nwww.bmj.com\/content\/348\/bmj.g2351<br \/>\n14.\tPatz J et al. Climate change: Challenges and<br \/>\nopportunities for global health. JAMA 2014;<br \/>\n312(15):1565-1580. Available at http:\/\/jama.ja-<br \/>\nmanetwork.com\/article.aspx?articleid=1909928<br \/>\n15.\tEnergy, Climate Change &#038; Environment. In-<br \/>\nternational Energy Agency 2014. Available at<br \/>\nhttps:\/\/www.iea.org\/Textbase\/npsum\/EEC-<br \/>\nC2014sum.pdf<br \/>\n16.\tClimate Change 2013: Intergovernmental Panel<br \/>\non Climate Change\u00a0 \u2013 Working Group 1. The<br \/>\nPhysical Science Basis.2013. Available at http:\/\/<br \/>\nwww.ipcc.ch\/report\/ar5\/wg1\/<br \/>\n17.\tWRI.CAIT Climate Data Explorer: Paris Con-<br \/>\ntributions Map.World Resources Institute 2015.<br \/>\nAvailable at http:\/\/cait.wri.org\/indc\/<br \/>\n18.\tSt.Louis M &#038; Hess J.Climate Change: Impacts<br \/>\non and Implications for Global Health. Am J<br \/>\nPrev Med. 2008; 35(5):527-538.<br \/>\n19.\tWHO Gender, Climate Change and Health.<br \/>\nWorld Health Organization. Available at http:\/\/<br \/>\nwww.who.int\/globalchange\/GenderClimat-<br \/>\neChangeHealthfinal.pdf?ua=1<br \/>\n20.\tLima call for climate action 2014. UNFCCC.<br \/>\nAvailable at http:\/\/newsroom.unfccc.int\/me-<br \/>\ndia\/167536\/auv_cop20_lima_call_for_climate_<br \/>\naction.pdf<br \/>\n21.\tGeneva Negotiating Text. UNFCCC 2015.<br \/>\nAvailable at http:\/\/unfccc.int\/resource\/<br \/>\ndocs\/2015\/adp2\/eng\/01.pdf<br \/>\n22.\tStreamlined and Consolidated Text. UNFC-<br \/>\nCC 2015; 11 June. Available at http:\/\/unfccc.<br \/>\nint\/files\/meetings\/bonn_jun_2015\/in-session\/<br \/>\napplication\/pdf\/adp2-9_i3_11jun2015t1630_<br \/>\nnp.pdf<br \/>\n23.\t.Working Document. UNFCCC 2015; 11 June.<br \/>\nAvailable at https:\/\/unfccc.int\/files\/bodies\/awg\/<br \/>\napplication\/pdf\/adp_2_9_wd_11062015@1645.<br \/>\npdf<br \/>\n24.\tCo-Chairs\u2019 Suggestions on the Way Forward<br \/>\nfor the Preparation of ADP 2.10. UNFCCC 11<br \/>\nJune 2015. Available at http:\/\/unfccc.int\/files\/<br \/>\nbodies\/awg\/application\/pdf\/way_forward_11_<br \/>\njune_-_edits_1026am.pdf<br \/>\n25.\tG7 Leaders\u2019 Declaration. 2015. Available at<br \/>\nhttps:\/\/www.g7germany.de\/Content\/DE\/_An-<br \/>\nlagen\/G8_G20\/2015-06-08-g7-abschluss-eng.<br \/>\npdf?__blob=publicationFile&#038;v=5<br \/>\n26.\tThe G7 and global health: inaction or incisive<br \/>\nleadership? The Lancet 2015; 385(9986):2433.<br \/>\n27.\tBowen K &#038; Ebi K. Governing the health<br \/>\nrisks of climate change: towards multi-sector<br \/>\nresponses. Current Opinion in Environmen-<br \/>\ntal Sustainability 2015; 12:80-85. Available at<br \/>\nhttp:\/\/www.sciencedirect.com\/science\/article\/<br \/>\npii\/S1877343514001171<br \/>\n28.\tRio Political Declaration on the Social Determi-<br \/>\nnants of Health. 2011. Available at http:\/\/www.<br \/>\nwho.int\/sdhconference\/declaration\/en\/<br \/>\n29.\tBarrett B, Charles J &#038; Temte J. Climate change,<br \/>\nhuman health and epidemiological transition.<br \/>\nPreventive Med. 2015; 70:69-75. Available at<br \/>\nhttp:\/\/www.sciencedirect.com\/science\/article\/<br \/>\npii\/S0091743514004563<br \/>\n30.\tAuerbach P. Physicians and the Environ-<br \/>\nment. JAMA 2008; 299(8):956-58. Avail-<br \/>\nable at http:\/\/jama.jamanetwork.com\/article.<br \/>\naspx?articleid=181509<br \/>\n31.\tDoha Declaration on Climate, Health and<br \/>\nWellbeing. Global Climate and Health Alli-<br \/>\nance 2012. Available at http:\/\/www.climateand-<br \/>\nhealthalliance.org\/news\/doha-declaration<br \/>\n32.\tOur Uncashed Dividend: The health benefits<br \/>\nof climate action. Global Climate and Health<br \/>\nAlliance 2012. Available at http:\/\/caha.org.au\/<br \/>\nwp-content\/uploads\/2010\/11\/OurUncashed-<br \/>\nDividend_CAHAandTCI_August2012.pdf<br \/>\n33.\tHutton G.The economics of health and climate<br \/>\nchange: key evidence for decision making. Glo-<br \/>\nbalization and Health. 2011; 7:18. Available at<br \/>\nhttp:\/\/www.who.int\/globalchange\/publications\/<br \/>\narticles\/GlobHealthCCHEconomicsRevie-<br \/>\nwHutton2011.pdf?ua=1<br \/>\n34.\tWMA Declaration of Delhi on Health and<br \/>\nClimate Change. World Medical Associa-<br \/>\ntion 2009. Available at https:\/\/www.wma.net\/<br \/>\nen\/30publications\/10policies\/c5\/index.html<br \/>\n35.\tWMA Statement on the Role of Physicians in<br \/>\nEnvironmental Issues. World Medical Asso-<br \/>\nciation 1988 (revised 2006). Available at http:\/\/<br \/>\nwww.wma.net\/en\/30publications\/10policies\/<br \/>\nd5\/index.html<br \/>\n36.\tWMA Health must be given higher priority<br \/>\nin climate summit say physician leaders. World<br \/>\nMedical Association [Press Release] 28 May<br \/>\n2015. Available at https:\/\/www.wma.net\/en\/40n<br \/>\news\/20archives\/2015\/2015_22\/index.html<br \/>\n37.\tUnited Nations Framework Convention on Cli-<br \/>\nmate Change. 1992. Available at http:\/\/unfccc.<br \/>\nint\/resource\/docs\/convkp\/conveng.pdf<br \/>\n38.\tKirton J et al. Connecting Climate Change and<br \/>\nHealth Through Global Summitry. World Med<br \/>\n&#038; Health Policy 2014; 6(1):73-100. Available<br \/>\nat http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/<br \/>\nwmh3.83\/abstract<br \/>\n39.\tTong S &#038; McMichael AJ. Climate Change<br \/>\nand Health: Risks and Adaptive Strategies.<br \/>\nReference Module in Earth Systems and En-<br \/>\nvironmental Sciences. 2013. Available at http:\/\/<br \/>\nwww.sciencedirect.com\/science\/article\/pii\/<br \/>\nB9780124095489017528<br \/>\n40.\tBMA Annual Representative Meeting Agenda.<br \/>\nBritish Medical Association. 2014. Available<br \/>\nat http:\/\/bma.org.uk\/working-for-change\/in-<br \/>\ndepth-arm-2014\/agenda\/finances-of-the-asso-<br \/>\nciation<br \/>\n41.\tWardrope A. Healthcare organisations and<br \/>\nfossil fuel divestment. The BMJ Blog 2014;<br \/>\n14 June. Available at http:\/\/blogs.bmj.com\/<br \/>\nbmj\/2014\/06\/27\/alistair-wardrope-healthcare-<br \/>\norganisations-and-fossil-fuel-divestment\/<br \/>\n42.\tHale I et al. Time to divest from the fossil-<br \/>\nfuel industry. Canadian Med Association J.<br \/>\n2014; 186(12):960. Available at http:\/\/search.<br \/>\nproquest.com\/openview\/2d7d039827e091b198f<br \/>\n03d634872aa80\/1?pq-origsite=gscholar<br \/>\n43.\tBennett H, Wilson N &#038; Woodward A. Time<br \/>\nfor the New Zealand health sector to divest all<br \/>\ninvestment funds out of fossil fuels. New Zea-<br \/>\nland Med J. 2015; 128(1414):6543. Available<br \/>\nat https:\/\/www.nzma.org.nz\/journal\/read-the-<br \/>\njournal\/all-issues\/2010-2019\/2015\/vol-128-no-<br \/>\n1414-15-may-2015\/6543<br \/>\n44.\tScherdel L et al. Fossil fuels are the new to-<br \/>\nbacco when it comes to health risk [Letter].The<br \/>\nGuardian. 2015; 29 April. Available at http:\/\/<br \/>\nwww.theguardian.com\/environment\/2015\/<br \/>\napr\/30\/fossil-fuels-new-tobacco-health-risk<br \/>\n45.\tHerman B. Health systems urged to divest<br \/>\nfossil-fuel stocks as UK doctors act. Modern<br \/>\nHealthcare 2014; 2 August. Available at http:\/\/<br \/>\nwww.modernhealthcare.com\/article\/20140802\/<br \/>\nMAGAZINE\/308029987<br \/>\n46.\tSena A, Corvalan C &#038; Ebi K. Climate Change,<br \/>\nExtreme Weather and Climate Events, and<br \/>\nHealth Impacts. Handbook of Global Environ-<br \/>\nmental Pollution, vol. 1 2014; 11 July: 605-613.<br \/>\nAvailable at http:\/\/link.springer.com\/referencew<br \/>\norkentry\/10.1007%2F978-94-007-5784-4_101<br \/>\n47.\tD\u2019Amato G et al. Climate change and respirato-<br \/>\nry diseases. Eur Respir Rev. 2014; 23(132):161-<br \/>\n169. Available at http:\/\/err.ersjournals.com\/con-<br \/>\ntent\/23\/132\/161.full.pdf+html<br \/>\n48.\tAnenberg S et al. Global air quality and health<br \/>\nco-benefits of mitigating near-term climate<br \/>\nchange through methane and black carbon<br \/>\nemission controls. Environmental Health Per-<br \/>\nspectives.2012; 120(6):831-9. Available at<\/p>\n<blockquote data-secret=\"7pv54TlzwJ\" class=\"wp-embedded-content\"><p><a href=\"https:\/\/ehp.niehs.nih.gov\/1104301\/\">Global Air Quality and Health Co-benefits of Mitigating Near-Term Climate Change through Methane and Black Carbon Emission          Controls<\/a><\/p><\/blockquote>\n<p><iframe class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" src=\"https:\/\/ehp.niehs.nih.gov\/1104301\/embed\/#?secret=7pv54TlzwJ\" data-secret=\"7pv54TlzwJ\" width=\"500\" height=\"282\" title=\"&#8220;Global Air Quality and Health Co-benefits of Mitigating Near-Term Climate Change through Methane and Black Carbon Emission          Controls&#8221; &#8212; Environmental Health Perspectives\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><br \/>\n49.\tBowen K &#038; Friel S. Climate change adapta-<br \/>\ntion: Where does global health fit in the agenda?<br \/>\nGlobalization &#038; Health. 2012; 8:10. Avail-<br \/>\nable at http:\/\/www.biomedcentral.com\/content\/<br \/>\npdf\/1744-8603-8-10.pdf<br \/>\n50.\t2015 Paris Climate Change Conference. Avail-<br \/>\nable at http:\/\/www.cop21.gouv.fr\/en<br \/>\n51.\tKyoto Protocol to the United Nations Frame-<br \/>\nwork Convention on Climate Change 1998.<br \/>\nAvailable at http:\/\/unfccc.int\/resource\/docs\/<br \/>\nconvkp\/kpeng.pdf<br \/>\n52.\tDoha Amendment to the Kyoto Protocol 2012.<br \/>\nAvailable at http:\/\/unfccc.int\/files\/kyoto_proto-<br \/>\ncol\/application\/pdf\/kp_doha_amendment_eng-<br \/>\nlish.pdf<br \/>\n53.\tPauw P. INDCs: A silver bullet for the climate<br \/>\nnegotiations, or empty talk? The Current Col-<br \/>\numn. 2015; 26 May. Available at https:\/\/www.<br \/>\ndie-gdi.de\/uploads\/media\/German_Develop-<br \/>\nment_Institute_Pauw_Mbeva_26.05.2015.pdf<br \/>\n100.Rudolph L &#038; Gould S. Climate Change and<br \/>\nHealth Inequities: A Framework for Action.<br \/>\nAnnals of Global Health. 2015; Article in Press.<br \/>\nAvailable at http:\/\/www.annalsofglobalhealth.<br \/>\norg\/article\/S2214-9996(15)01206-0\/abstract<br \/>\n101.Alexander S, Nicholson K &#038; Wiseman J. Fossil<br \/>\nFree: The Development and Significance of the<br \/>\nFossil Fuel Divestment Movement. Melbourne<br \/>\nSustainable Society Institute Issues Paper no.<br \/>\n4. 2014; Sept. Available at http:\/\/sustainable.<br \/>\nunimelb.edu.au\/sites\/default\/files\/docs\/MSSI-<br \/>\nIssuesPaper-4_Divestment_2014.pdf<br \/>\n102.Health Care Without Harm. Available at htt-<br \/>\nps:\/\/noharm.org\/<br \/>\n103.IFMSA Proposal from IFMSA on Draft El-<br \/>\nements under ADP\u00a0\u2013 Health Elements. Inter-<br \/>\nnational Federation of Medical Students\u2019 As-<br \/>\nsociations 2014. Available at http:\/\/unfccc.int\/<br \/>\nresource\/docs\/2014\/smsn\/ngo\/483.pdf<br \/>\n104.IFMSA IFMSA Policy Brief\u00a0 \u2013 UNFCCC<br \/>\nADP 2.9. International Federation of Medical<br \/>\nStudents\u2019Associations. 2015. Available at http:\/\/<br \/>\nissuu.com\/ifmsa\/docs\/ifmsa_policybrief_adp2.9<br \/>\n105.Petrin-Desrosiers C et al.Climate and Health\u00a0\u2013<br \/>\na call for action from tomorrow\u2019s global leaders.<br \/>\nPLoS Blog 2013; 16 November. Available at<br \/>\nhttp:\/\/blogs.plos.org\/globalhealth\/2013\/11\/<br \/>\nifmsa-cop\/<br \/>\n54.\tWMA Climate Change and Health Care Ad-<br \/>\nvocacy Kit. World Medical Association 2009.<br \/>\nAvailable at https:\/\/www.wma.net\/en\/20activiti<br \/>\nes\/30publichealth\/30healthenvironment\/Advo-<br \/>\ncacy_kit.pdf<br \/>\n55.\tWHPA Statement on Health and Climate<br \/>\nChange. World Health Professions Alliance<br \/>\n2009. Available at http:\/\/www.whpa.org\/jsCli-<br \/>\nmate_change10.htm<br \/>\n56.\tWHO Climate change agreement critical to<br \/>\npublic health. World Health Organization<br \/>\n2015; 2 June. Available at http:\/\/www.who.<br \/>\nint\/globalchange\/mediacentre\/news\/climate-<br \/>\nchange\/en\/<br \/>\nMD, MIH Yassen Tcholakov,<br \/>\nMcGill University, Canada;<br \/>\nMD, JD, MPH Elizabeth Wiley,<br \/>\nUniversity of Maryland, USA;<br \/>\nMD Thorsten Hornung,<br \/>\nUniversity of Bonn, Germany;<br \/>\nMD, MPH, DTMH Xaviour Walker,<br \/>\nJohns Hopkins Bloomberg School<br \/>\nof Public Health, USA;<br \/>\nMD Diogo Martins,<br \/>\nUniversity of Beira Interior, Portugal;<br \/>\nMD Arthur Mello,<br \/>\nUniversity of the State of Par\u00e1, Brazil;<br \/>\nMD Deborah Vozzella Hall,<br \/>\nUniversity of Connecticut, USA<br \/>\nMD Caline Mattar,<br \/>\nWashington University in St Louis, USA;<br \/>\nMD, MSc, BSc Kimberly Williams,<br \/>\nUniversity of Calgary, Canada;<br \/>\nMBE, MSW, Candidate<br \/>\nDonna Castelblanco, University<br \/>\nof Pennsylvania, USA;<br \/>\nMD Candidate Claudel P-Desrosiers,<br \/>\nUniversity of Montreal<br \/>\nMBChB, BMedSci, Sudhvir Singh,<br \/>\nEAT Initiative, Norway;<br \/>\nMD Renzo Guinto,<br \/>\nHealth Care Without Harm-Asia;<br \/>\nReimagine Global Health, Philippines;<br \/>\nMD Candidate Skander Essafi,<br \/>\nUniversity of Sousse, Tunisia;<br \/>\nMD Candidate Samantha De Leon,<br \/>\nUniversity of Panama, Panama<br \/>\nE-mail: yassen.tcholakov@mail.mcgill.ca<br \/>\nMolly Mettler<br \/>\nMore Good Days: Person-Centered Care<br \/>\nat\u00a0the End of Life<br \/>\n\u201cModern medicine is good at staving off death<br \/>\nwith aggressive interventions \u2013 and bad at<br \/>\nknowing when to focus, instead, on improv-<br \/>\ning the days that terminal patients have<br \/>\nleft\u201d\u00a0[1].<br \/>\nAre we asking the right question?<br \/>\nIs more care better than less care at end of<br \/>\nlife? It\u2019s a highly personal choice calling for<br \/>\na person-centered response.<br \/>\nAccording to Pew Research Center polls,<br \/>\nAmericans\u2019preferences for end-of-life med-<br \/>\nical treatment vary depending on the exact<br \/>\ncircumstances they might face [2]:<br \/>\n\u2022\t 57% would tell their doctors to stop treat-<br \/>\nment if they had a disease with no hope<br \/>\nof improvement and were suffering a<br \/>\ngreat deal of pain;<br \/>\n\u2022\t 52% would ask their doctors to stop treat-<br \/>\nment if they had an incurable disease and<br \/>\nwere totally dependent on someone else<br \/>\nfor their care;<br \/>\nBACK TO CONTENTS<br \/>\n120<br \/>\nPerson Centered Medicine UNITED STATES OF AMERICA<br \/>\n\u2022\t But about 35% (about a third) say they<br \/>\nwould tell their doctors to do everything<br \/>\npossible to keep them alive\u00a0\u2013 even in dire<br \/>\ncircumstances, such as having a disease<br \/>\nwith no hope of improvement and expe-<br \/>\nriencing a great deal of pain.<br \/>\nIn light of this variation, as we strive to<br \/>\nmake all care person-centered, perhaps we<br \/>\nneed to expand, even change, the traditional<br \/>\nquestions around end of life care.<br \/>\nIn addition to asking what level of care pa-<br \/>\ntients want at the end of their lives-curative<br \/>\ncare or comfort care, more care or less care,<br \/>\nin other words: \u201cWhat is a good death for<br \/>\nyou?\u201d\u00a0\u2013 perhaps we should be asking each pa-<br \/>\ntient: \u201cWhat is a good life for you? What, for<br \/>\nyou, is a good day? What can we do together<br \/>\nto ensure that you have more good days?\u201d<br \/>\nGoals of care, then, can be refocused on<br \/>\nmaximizing the number of \u201cgood days\u201d that<br \/>\nthe patient can enjoy, ensuring care that is<br \/>\ntruly patient centered [2].<br \/>\nWe are failing our<br \/>\npatients at end of life<br \/>\nWoody Allen, an American comedian, fa-<br \/>\nmously said, \u201cI\u2019m not afraid of dying, I just<br \/>\ndon\u2019t want to be there when it happens.\u201d<br \/>\nMost of us are more realistic, and we still<br \/>\nhope for a good death.<br \/>\nIn a narrative study of patients, physicians,<br \/>\nfamily members and others, several com-<br \/>\nmon themes about what constitutes a good<br \/>\ndeath emerge: freedom from pain, the sense<br \/>\nof a life well lived, and a sense of commu-<br \/>\nnity [3]. However, while people hope for a<br \/>\n\u201cgood death\u201d, they don\u2019t necessarily get one.<br \/>\nInstead, research shows that although 70%<br \/>\npatients want to die at home, approximately<br \/>\n60% die in hospitals, nursing homes or oth-<br \/>\ner care settings [4].<br \/>\nPeople are getting expensive high-tech<br \/>\ncare when they prefer more conservative<br \/>\ntreatment. Overtreatment in the form of<br \/>\naggressive interventions-repeated hospi-<br \/>\ntalizations, intensive care, cardiac resusci-<br \/>\ntation, multiple rounds of chemotherapy,<br \/>\netc.-is costly. In the US, approximately<br \/>\n30% of Medicare funding goes to 5% of<br \/>\nbeneficiaries who die. Acute care, not com-<br \/>\nfort care, accounts for 78% of costs in-<br \/>\ncurred in the final year of life. One-third<br \/>\nof those expenditures are spent in the last<br \/>\nmonth of life [5].<br \/>\nIs Geography Destiny?<br \/>\nEven though patients often prefer more<br \/>\nconservative end-of-life care than they<br \/>\nactually receive, a patient\u2019s wishes can be<br \/>\nless influential than the practice patterns<br \/>\nat the hospital where care is delivered. In<br \/>\nother words, the degree to which care at<br \/>\nthe end of life is most closely aligned with<br \/>\na patient\u2019s values and preferences may de-<br \/>\npend more on where one dies than on how<br \/>\none dies [6].<br \/>\nTracking these geographical differences,<br \/>\nthe authors of the Dartmouth Atlas of<br \/>\nHealth Care\u2019s report on end of life care<br \/>\nsuggest:<br \/>\nThese findings underscore the importance of in-<br \/>\nnovative approaches to care that help ensure<br \/>\nthat patients and their families engage in dis-<br \/>\ncussions of their preferences before they become<br \/>\nseriously ill and that providers respect these<br \/>\npreferences [7].<br \/>\nPatient Preferences at End of<br \/>\nLife: Arriving at a Tipping Point<br \/>\nThese hoped-for \u201cinnovative approaches to<br \/>\ncare\u201dinclude advanced care planning (ACP),<br \/>\na series of actions to help care providers un-<br \/>\nderstand what a patient\u2019s treatment pref-<br \/>\nerences would be if that patient could not<br \/>\nspeak for herself. Driven in part by the mis-<br \/>\nmatch in goals between what patients want<br \/>\nand what they get in end of life care, and by<br \/>\nthe desire to align care with outcomes that<br \/>\nmatter to the patient, several patient educa-<br \/>\ntion and engagement programs have begun<br \/>\nto emphasize the importance of ACP. (See<br \/>\nthe Resource List below for a small sample<br \/>\nof current programs.)<br \/>\nIn years past, advance care planning was<br \/>\na political \u201chot button\u201d for physicians and<br \/>\nprovider systems. However, changes are<br \/>\nafoot that indicate that embracing ad-<br \/>\nvanced care planning as a vital component<br \/>\nof person-centered care has reached a tip-<br \/>\nping point.For example,in the US,two new<br \/>\nproposed Medicare billing codes for ad-<br \/>\nvance care planning would allow physicians<br \/>\nand other qualified health professionals to<br \/>\nbe reimbursed for time spent explaining and<br \/>\ndiscussing advance directives during a visit.<br \/>\nReimbursing clinicians for this use of their<br \/>\ntime with their patients supports care deliv-<br \/>\nery that is \u201chigh-quality,comprehensive and<br \/>\nperson-centered\u201d [8].<br \/>\nThe Goal: More Good Days<br \/>\nWe need to plan our lives to the end, be-<br \/>\nyond the administrative work of complet-<br \/>\ning advance directives. We need to plan<br \/>\nto go even further than the very impor-<br \/>\ntant discussions about treatment choices<br \/>\nand documentation of health care proxies.<br \/>\nEqually important in making end-of-life<br \/>\ncare person-centered is the exploration of<br \/>\nmore good days.<br \/>\nA focus on more good days engages the<br \/>\npatient by asking: \u201cWhat is a good day for<br \/>\nyou?\u201d<br \/>\nEach person\u2019s \u201cgood day\u201d is uniquely their<br \/>\nown. For some, any day alive is a good day.<br \/>\nFor others, a good day may mean the op-<br \/>\nportunity to enjoy an activity or the com-<br \/>\npany of loved ones. With this in mind,<br \/>\nquestions about advanced care options help<br \/>\npatients discover how likely each proposed<br \/>\ntreatment will create more good days than it<br \/>\ntakes away. With the focus on good days, it<br \/>\nPerson Centered Medicine<br \/>\nbecomes easier to discuss which treatments<br \/>\nmight result in the greatest net number of<br \/>\ngood days.That can be a welcome shift from<br \/>\nanswering the question of more care vs. less<br \/>\ncare.<br \/>\nPerhaps truly person-centered care in ad-<br \/>\nvanced illness is not so much about how<br \/>\nwe plan the end of our lives, but rather how<br \/>\nwe want to live our lives to the end. (Focus<br \/>\ngroups and provider interviews we\u2019ve con-<br \/>\nducted suggest that this approach can open<br \/>\nup communication among patients, families<br \/>\nand providers.)<br \/>\nPatients and families can help protect and<br \/>\nsupport \u201cgood days\u201d by becoming well-<br \/>\ninformed about treatment options and<br \/>\ntheir potential clinical outcomes, and by<br \/>\nbecoming well-prepared for what is likely<br \/>\nto happen throughout the course of an ill-<br \/>\nness. Framing care planning around more<br \/>\ngood days would mean making decisions<br \/>\nthat protect \u201cgood days,\u201d that is, making<br \/>\ndecisions based upon a balance of two<br \/>\nthings:<br \/>\n\u2022\t The chance that any proposed treatment<br \/>\nwill extend the number of good days for the<br \/>\npatient.<br \/>\n\u2022\t The chance that any proposed treatment<br \/>\nwill reduce the number of good days for the<br \/>\npatient.<br \/>\nUsing a person-centered approach focus-<br \/>\ning on more good days, patients, families<br \/>\nand caregivers gain from each other these<br \/>\nbenefits:<br \/>\n\u2022\t Understanding of the patient\u2019s treatment<br \/>\nand care options and each option\u2019s likely<br \/>\nimpact on remaining good days.<br \/>\n\u2022\t Understanding of the patient\u2019s options<br \/>\nfor effective pain control either at home<br \/>\nor in care facilities.<br \/>\n\u2022\t Emotional support and practical tips for<br \/>\nwhen the patient chooses to receive late<br \/>\nlife care in their own home with family<br \/>\nand friends present.<br \/>\n\u2022\t Consensus and acceptance among family<br \/>\nmembers for a chosen care plan or ad-<br \/>\nvance directive.<br \/>\nConclusion<br \/>\nGood days become particularly precious<br \/>\nwhen one\u2019s health is fragile and failing.<br \/>\nChoosing a more good days approach is to<br \/>\nseek to improve patient understanding and<br \/>\nto help them get care aligned with what<br \/>\nthey prefer and want. In no way does it sug-<br \/>\ngest that patients be deterred from making<br \/>\na choice to pursue life-extending treatment.<br \/>\nFor some people, fighting for life every inch<br \/>\nof the way could constitute a day well-spent.<br \/>\nWe, as care professionals, cannot judge any<br \/>\npatient\u2019s choices if we seek to be person-<br \/>\ncentered in our care.<br \/>\nMaking it possible to gain clarity about<br \/>\nmore good days and helping people express<br \/>\ntheir preferences to their families and care<br \/>\nproviders will help make care, right up until<br \/>\nthe end, truly person-centered.<br \/>\nResource List: USA-based programs<br \/>\nthat promote patient-centered<br \/>\nAdvance Care Planning:<br \/>\n\u2022\t ACP Decisions: www.acpdecisions.org<br \/>\n\u2022\t Advanced Illness Management (AIM) \u00ae:<br \/>\nhttp:\/\/www.sutterhealth.org\/quality\/focus\/<br \/>\nadvanced-illness-management.html<br \/>\n\u2022\t Healthwise Advanced Care Planning<br \/>\nAssets: http:\/\/www.healthwise.org\/docs\/<br \/>\nDOCUMENT\/8349.pdf<br \/>\n\u2022\t Respecting Choices\u00ae: http:\/\/www.<br \/>\ngundersenhealth.org\/respecting-choices<br \/>\n\u2022\t The Conversation Project: http:\/\/thecon-<br \/>\nversationproject.org<br \/>\nReferences<br \/>\n1.\t Gawande A. 2010. Letting Go.The New Yorker,<br \/>\nAugust 2.<br \/>\n2.\t Kemper D. 2013. More Good Days. White Pa-<br \/>\nper, Boise: Healthwise.<br \/>\n3.\t Views on End of Life Medical Treatments. Pew<br \/>\nResearch Center. 2013. www.pewforum.org.<br \/>\nNovember 11. Accessed April 10, 2015. http:\/\/<br \/>\nwww.pewforum.org\/2013\/11\/21\/views-on-end-<br \/>\nof-life-medical-treatments\/.<br \/>\n4.\t Facing Death.Facts and Figures.2015 www.pbs.<br \/>\norg. Accessed April 10, 2015. http:\/\/www.pbs.<br \/>\norg\/wgbh\/pages\/frontline\/facing-death\/facts-<br \/>\nand-figures\/<br \/>\n5.\t Zhang B. et al. 2009. Health care costs in the<br \/>\nlast week of life. Arch Intern Med.2009; 169 (5):<br \/>\n480>-488<br \/>\n6.\t End-of-Life Care. Dartmouth Atlas of Health<br \/>\nCare. 2015. http:\/\/www.dartmouthaltlas.org.<br \/>\nAccessed April 10, 2015. http:\/\/www.dart-<br \/>\nmouthatlas.org\/keyissues\/issue.aspx?con=2944<br \/>\n\t \u201cPeople with severe chronic illness who live in com-<br \/>\nmunities where they receive more intensive inpa-<br \/>\ntient care do not have improved survival, better<br \/>\nquality of life, or better access to care than patients<br \/>\nwho live in communities where they receive less<br \/>\ncare. Patients\u2019 experience of care, however, differs<br \/>\ndramatically; they receive a much more aggressive<br \/>\nbrand of medicine, seeing medical specialists more<br \/>\nfrequently, spending more days in the hospital, and<br \/>\ndying in an ICU more often than those in lower in-<br \/>\ntensity regions.\u201d<br \/>\n7.\t Ibid. Dartmouth Atlas of Health Care. 2015,<br \/>\n8.\t C-TAC. C-TAC Applauds Landmark 2016<br \/>\nMedicare Physician Fee Schedule (PFS) Pro-<br \/>\nposed Rule on Advance Care Planning. The<br \/>\nCoalition to Transform Advanced Care 2015.<br \/>\nAccessed August 24, 2015. http:\/\/www.thectac.<br \/>\norg\/2015\/07\/3912<br \/>\nMolly Mettler,<br \/>\nSenior Vice President, Mission<br \/>\nHealthwise<br \/>\nBoise, ID 83702<br \/>\nUSA<br \/>\nE-mail: mmettler@healthwise.org<br \/>\nHealthwise is a not-for-profit consumer health infor-<br \/>\nmation organization whose mission is \u201cto help people<br \/>\nmake better health decisions.\u201d<br \/>\nUNITED STATES OF AMERICA<br \/>\nBACK TO CONTENTS<br \/>\nIV<\/p>\n"},"caption":{"rendered":"<p>wmj201503 COUNTRY vol. 61 MedicalWorld Journal Official Journal of The World Medical Association, Inc. ISSN 2256-0580 Nr. 3, October 2015 Contents Doctor in the World and Medicines . . . . . . . . . . . . . . . . . . . . . . . . . . . . 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